Publications by authors named "Martin Valachovic"

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The replacement of ergosterol with alternative sterols affects the physiological function of the yeast plasma membrane, including its H-ATPase activity and resistance to antifungal drugs.
Marie Kodedová, Martin Valachovič, Hana Sychrová

Microbes Infect· February 2025

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The subtherapeutic dose of valproic acid induces the activity of cardiolipin-dependent proteins.
Paulina Horonyova, Ivana Durisova, Petra Cermakova, Lenka Babelova, Barbora Buckova, Martin Valachovic

Biochim Biophys Acta Bioenerg· November 2024

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Lipid droplets control the negative effect of non-yeast sterols in membranes of Saccharomyces cerevisiae under hypoxic stress.
Lívia Petrisková, Marie Kodedová, Mária Balážová, Hana Sychrová, Martin Valachovič

Biochim Biophys Acta Mol Cell Biol Lipids· October 2024

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Yeast perilipin Pet10p/Pln1p interacts with Erg6p in ergosterol metabolism.
Martina Garaiova, Yunfeng Ding, Roman Holic, Martin Valachovic, Congyan Zhang

Biochim Biophys Acta Mol Cell Biol Lipids· August 2024

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Yeast Sec14-like lipid transfer proteins Pdr16 and Pdr17 bind and transfer the ergosterol precursor lanosterol in addition to phosphatidylinositol.
Dominik Šťastný, Lívia Petrisková, Dana Tahotná, Jacob Bauer, Lucia Pokorná

FEBS Lett· February 2023

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Erg6p is essential for antifungal drug resistance, plasma membrane properties and cell wall integrity in Candida glabrata.
Daniel Elias, Nora Toth Hervay, Juraj Jacko, Marcela Morvova, Martin Valachovic

FEMS Yeast Res· September 2022

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Blocking phosphatidylglycerol degradation in yeast defective in cardiolipin remodeling results in a new model of the Barth syndrome cellular phenotype.
Paulína Káňovičová, Petra Čermáková, Dominika Kubalová, Lenka Bábelová, Petra Veselá

J Biol Chem· January 2022

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UPC2 gene deletion modifies sterol homeostasis and susceptibility to metabolic inhibitors in Kluyveromyces lactis.
Nora Toth Hervay, Alexandra Bencova, Martin Valachovic, Marcela Morvova, Yvetta Gbelska

Yeast· December 2020

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The Absence of PDR16 Gene Restricts the Overexpression of CaSNQ2 Gene in the Presence of Fluconazole in Candida albicans.
Alexandra Bencova, Eduard Goffa, Marcela Morvova, Martin Valachovic, Peter Griač

Mycopathologia· June 2020

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Squalene lipotoxicity in a lipid droplet-less yeast mutant is linked to plasma membrane dysfunction.
Zsófia Csáky, Martina Garaiová, Marie Kodedová, Martin Valachovič, Hana Sychrová

Yeast· January 2020

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Mutations in the nucleotide-binding domain of putative sterol importers Aus1 and Pdr11 selectively affect utilization of exogenous sterol species in yeast.
Marek Papay, Cornelia Klein, Ivan Hapala, Livia Petriskova, Karl Kuchler, Martin Valachovic

Yeast· January 2020

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Variations in yeast plasma-membrane lipid composition affect killing activity of three families of insect antifungal peptides.
Marie Kodedová, Martin Valachovič, Zsófia Csáky, Hana Sychrová

Cell Microbiol· December 2019

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Biosynthetic Approaches to Squalene Production: The Case of Yeast.
Martin Valachovič, Ivan Hapala

Methods Mol Biol· January 2018

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Identification of Yeast Mutants Exhibiting Altered Sensitivity to Valinomycin and Nigericin Demonstrate Pleiotropic Effects of Ionophores on Cellular Processes.
Michaela Jakubkova, Vladimira Dzugasova, Dominika Truban, Lenka Abelovska, Ingrid Bhatia-Kissova, Martin Valachovic

PLoS One· June 2017

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ERG6 gene deletion modifies Kluyveromyces lactis susceptibility to various growth inhibitors.
Alexandra Konecna, Nora Toth Hervay, Martin Valachovic, Yvetta Gbelska

Yeast· December 2016

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Squalene is lipotoxic to yeast cells defective in lipid droplet biogenesis.
Martin Valachovic, Martina Garaiova, Roman Holic, Ivan Hapala

Biochem Biophys Res Commun· January 2016

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ABC proteins in yeast and fungal pathogens.
Cornelia Klein, Karl Kuchler, Martin Valachovic

Essays Biochem· September 2011

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The role of ABC proteins Aus1p and Pdr11p in the uptake of external sterols in yeast: dehydroergosterol fluorescence study.
Peter Kohut, Daniel Wüstner, Lucia Hronska, Karl Kuchler, Ivan Hapala, Martin Valachovic

Biochem Biophys Res Commun· January 2011

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Chemosensitisation of drug-resistant and drug-sensitive yeast cells to antifungals.
Jana Cernicka, Zuzana Kozovska, Martina Hnatova, Martin Valachovic, Ivan Hapala

Int J Antimicrob Agents· February 2007

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Cumulative mutations affecting sterol biosynthesis in the yeast Saccharomyces cerevisiae result in synthetic lethality that is suppressed by alterations in sphingolipid profiles.
Martin Valachovic, Bart M Bareither, M Shah Alam Bhuiyan, James Eckstein, Robert Barbuch

Genetics· August 2006

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The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p).
Caiqing Mo, Martin Valachovic, Martin Bard

Biochim Biophys Acta· November 2004

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Low concentrations of the non-ionic detergent Nonidet P-40 interfere with sterol biogenesis and viability of the yeast Saccharomyces cerevisiae.
Lucia Hronská, Zuzana Mrózová, Martin Valachovic, Ivan Hapala

FEMS Microbiol Lett· September 2004

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A mutation in sphingolipid synthesis suppresses defects in yeast ergosterol metabolism.
Martin Valachovic, Lisa I Wilcox, Stephen L Sturley, Martin Bard

Lipids· August 2004

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Transcription of the yeast iron regulon does not respond directly to iron but rather to iron-sulfur cluster biosynthesis.
Opal S Chen, Robert J Crisp, Martin Valachovic, Martin Bard, Dennis R Winge

J Biol Chem· July 2004

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Heme-regulated expression of two yeast acyl-CoA:sterol acyltransferases is involved in the specific response of sterol esterification to anaerobiosis.
Martin Valachovic, Vlasta Klobucníková, Peter Griac, Ivan Hapala

FEMS Microbiol Lett· January 2002

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