Publications by authors named "Martin Zenke"

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Hijack the HiJAKer: rethinking therapy for JAK2-mutant MPN.
Martin Zenke, Steffen Koschmieder

Blood· November 2025

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CREB regulates Foxp3ST-2 T with enhanced IL-10 production.
Sudheendra Hebbar Subramanyam, Judit Turyne Hriczko, Saskia Schulz, Thomas Look, Tannaz Goodarzi, Martin Zenke

Front Immunol· August 2025

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The significance of PAX5 in Merkel cell carcinoma.
Emil Chteinberg, Julia Kolarova, Julia Vogt, Amanda Macamo, Felix Bormann, Martin Zenke

J Pathol· May 2025

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DNA methylation in primary myelofibrosis is partly associated with driver mutations and distinct from other myeloid malignancies.
Esra Dursun Torlak, Vithurithra Tharmapalan, Kim Kricheldorf, Joelle Schifflers, Madeline Caduc, Martin Zenke

Clin Epigenetics· May 2025

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Deciphering the complex clonal heterogeneity of polycythemia vera and the response to interferon alfa.
Milena Kalmer, Martin Grasshoff, Tiago Maié, Kristina Pannen, Marcelo A S Toledo, Martin Zenke

Blood Adv· April 2025

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Automated CRISPR/Cas9-based genome editing of human pluripotent stem cells using the StemCellFactory.
Bastian Nießing, Yannik Breitkreuz, Andreas Elanzew, Marcelo A S de Toledo, Peter Vajs, Martin Zenke

Front Bioeng Biotechnol· September 2024

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Generation of a conditional cellular senescence model using proximal tubule cells and fibroblasts from human kidneys.
Xiaohang Shao, Huaming Xu, Hyojin Kim, Sadaf Ljaz, Fabian Beier, Martin Zenke

Cell Death Discov· August 2024

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The pain target Na1.7 is expressed late during human iPS cell differentiation into sensory neurons as determined in high-resolution imaging.
Yi Liu, Rachna Balaji, Marcelo A Szymanski de Toledo, Sabrina Ernst, Petra Hautvast, Martin Zenke

Pflugers Arch· June 2024

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Generation of a TMEM43 knockout human induced pluripotent stem cell line (HDZi003-A-1) using CRISPR/Cas9.
Sandra Ratnavadivel, Joline Dammeier, Anna Gaertner, Marcelo A Szymanski de Toledo, Martin Zenke

Stem Cell Res· April 2024

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Epigenetic and Transcriptional Shifts in Human Neural Stem Cells after Reprogramming into Induced Pluripotent Stem Cells and Subsequent Redifferentiation.
Carolin Haubenreich, Michael Lenz, Andreas Schuppert, Michael Peitz, Philipp Koch, Martin Zenke

Int J Mol Sci· March 2024

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Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche.
Niclas Flosdorf, Janik Böhnke, Marcelo A S de Toledo, Niklas Lutterbach, Vanesa Gómez Lerma, Martin Zenke

Stem Cell Reports· February 2024

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In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime naïve T cells.
Anette Christ, Sanne L Maas, Han Jin, Chang Lu, Bart Legein, Martin Zenke

Free Radic Biol Med· January 2024

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Guidelines for mouse and human DC generation.
Manfred B Lutz, Shafaqat Ali, Cindy Audiger, Stella E Autenrieth, Luciana Berod, Martin Zenke

Eur J Immunol· November 2023

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Cellular aging is accelerated in the malignant clone of myeloproliferative neoplasms.
Margherita Vieri, Vithurithra Tharmapalan, Milena Kalmer, Julian Baumeister, Miloš Nikolić, Martin Zenke

Blood Cancer J· November 2023

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The telomerase inhibitor imetelstat differentially targets JAK2V617F versus CALR mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling.
Kathrin Olschok, Bianca Altenburg, Marcelo A S de Toledo, Angela Maurer, Anne Abels, Martin Zenke

Front Oncol· October 2023

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Fully functional monocytic MDSC generation from the murine HoxB8 cell line.
Haisam Alattar, Huaming Xu, Martin Zenke, Manfred B Lutz

Eur J Immunol· September 2023

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Capitalizing on paradoxical activation of the mitogen-activated protein kinase pathway for treatment of Imatinib-resistant mast cell leukemia.
Thomas Wilhelm, Marcelo A S Toledo, Ilka Simons, Christian Stuth, Vrinda Mohta, Martin Zenke

Hematol Oncol· August 2023

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Met-Signaling Controls Dendritic Cell Migration in Skin by Regulating Podosome Formation and Function.
Ahmed E I Hamouda, Carmen Schalla, Antonio Sechi, Martin Zenke, Rebekka K Schneider

J Invest Dermatol· August 2023

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Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF.
Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Boehme, Martin Zenke

Nat Immunol· March 2023

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YAP1 is essential for self-organized differentiation of pluripotent stem cells.
Kira Zeevaert, Roman Goetzke, Mohamed H Elsafi Mabrouk, Marco Schmidt, Catharina Maaßen, Martin Zenke

Biomater Adv· March 2023

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RGT: a toolbox for the integrative analysis of high throughput regulatory genomics data.
Zhijian Li, Chao-Chung Kuo, Fabio Ticconi, Mina Shaigan, Julia Gehrmann, Martin Zenke

BMC Bioinformatics· March 2023

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A lncRNA identifies enhancer element in negative feedback control of dendritic cell differentiation.
Huaming Xu, Zhijian Li, Chao-Chung Kuo, Katrin Götz, Thomas Look, Martin Zenke

Elife· March 2023

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KIT D816V Mast Cells Derived from Induced Pluripotent Stem Cells Recapitulate Systemic Mastocytosis Transcriptional Profile.
Marcelo A S de Toledo, Xuhuang Fu, Tiago Maié, Eva M Buhl, Katrin Götz, Martin Zenke

Int J Mol Sci· March 2023

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Polyelectrolyte Coating of Ferumoxytol Differentially Impacts the Labeling of Inflammatory and Steady-State Dendritic Cell Subtypes.
Nehar Celikkin, John E Wong, Martin Zenke, Thomas Hieronymus

Biomedicines· December 2022

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Towards personalized medicine with iPS cell technology: a case report of advanced systemic mastocytosis with associated eosinophilia.
Salim Atakhanov, Deborah Christen, Benjamin Rolles, Herdit M Schüler, Jens Panse, Martin Zenke

Ann Hematol· November 2022

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