Publications by authors named "Thomas Look"

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CREB regulates Foxp3ST-2 T with enhanced IL-10 production.
Sudheendra Hebbar Subramanyam, Judit Turyne Hriczko, Saskia Schulz, Thomas Look, Tannaz Goodarzi

Front Immunol· August 2025

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Seq2Karyotype (S2K): A Method for Karyotyping Using Single-Sample Whole-Genome Sequencing Data.
Limeng Pu, Karol Szlachta, Virginia Valentine, Meiling Jin, Sivaraman Natarajan, Thomas Look

bioRxiv· August 2025

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KAT6A/B inhibition synergizes with retinoic acid and enhances the efficacy of GD2-targeted immunotherapy in neuroblastoma.
Nina Weichert-Leahey, Alla Berezovskaya, Mark W Zimmerman, Francesca Alvarez-Calderon, Marlana Winschel, A Thomas Look

bioRxiv· July 2025

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Multitargeted Reduction of Inflammation and Atherosclerosis in -deficient CHIP via XPO1 Inhibition and Atf3 restoration.
Nicole Prutsch, Amélie Vromman, Brittaney Leeper, Mengyu Chen, Julia Keating, A Thomas Look

bioRxiv· June 2025

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Transcription factor cooperativity at a GATA3 tandem DNA sequence determines oncogenic enhancer-mediated activation.
Joana R Costa, Yang Li, Nurkaiyisah Zaal Anuar, David O'Connor, Sunniyat Rahman, A Thomas Look

Cell Rep· May 2025

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CAR T cells, CAR NK cells, and CAR macrophages exhibit distinct traits in glioma models but are similarly enhanced when combined with cytokines.
Thomas Look, Roman Sankowski, Manon Bouzereau, Serena Fazio, Miaomiao Sun

Cell Rep Med· February 2025

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Accurate Measurement of Cell Number-Normalized Differential Gene Expression in Cells Treated With Retinoic Acid.
Nina Weichert-Leahey, Mark W Zimmerman, Alla Berezovskaya, A Thomas Look, Brian J Abraham

Bio Protoc· November 2024

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An IL-7 fusion protein targeting EDA fibronectin upregulates TCF1 on CD8+ T-cells, preferentially accumulates to neoplastic lesions, and boosts PD-1 blockade.
Cesare Di Nitto, Domenico Ravazza, Ettore Gilardoni, Thomas Look, Miaomiao Sun

J Immunother Cancer· August 2024

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Synthetic mRNAs Containing Minimalistic Untranslated Regions Are Highly Functional In Vitro and In Vivo.
Shahab Mamaghani, Rocco Roberto Penna, Julia Frei, Conrad Wyss, Mark Mellett, Thomas Look

Cells· July 2024

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T-Lymphoblastic Lymphoma Cells Express High Levels of BCL2, S1P1, and ICAM1, Leading to a Blockade of Tumor Cell Intravasation.
Hui Feng, David L Stachura, Richard M White, Alejandro Gutierrez, Lu Zhang, A Thomas Look

Cancer Cell· June 2024

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A novel strategy to generate immunocytokines with activity-on-demand using small molecule inhibitors.
Giulia Rotta, Ettore Gilardoni, Domenico Ravazza, Jacqueline Mock, Frauke Seehusen, Thomas Look

EMBO Mol Med· April 2024

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STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma.
Nicole Prutsch, Shuning He, Alla Berezovskaya, Adam D Durbin, Neekesh V Dharia, A Thomas Look

Cell Rep Med· March 2024

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Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma.
Daniel Kirschenbaum, Ken Xie, Florian Ingelfinger, Yonatan Katzenelenbogen, Kathleen Abadie, Thomas Look

Cell· January 2024

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Protocol for the expansion of mouse immune effector cells for in vitro and in vivo studies.
Thomas Look, Hanna Meister, Michael Weller, Tobias Weiss

STAR Protoc· December 2023

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ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors.
Lu Wang, Tze King Tan, Hyoju Kim, Dennis Kappei, Shi Hao Tan, A Thomas Look

Cell Rep· December 2023

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Depletion of results in age-dependent changes in DNA methylation and gene expression in a zebrafish model of myelodysplastic syndrome.
Yaseswini Neelamraju, Evisa Gjini, Sagar Chhangawala, Hao Fan, Shuning He, A Thomas Look

Front Hematol· September 2023

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Design of the Lanthanum hexaboride based plasma source for the large plasma device at UCLA.
Yuchen Qian, Walter Gekelman, Patrick Pribyl, Tom Sketchley, Shreekrishna Tripathi, Thomas Look

Rev Sci Instrum· August 2023

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Synthetic lethal targeting of TET2-mutant haematopoietic stem and progenitor cells by XPO1 inhibitors.
Chang-Bin Jing, Nicole Prutsch, Shuning He, Mark W Zimmerman, Yosef Landesman, A Thomas Look

Br J Haematol· May 2023

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Genetic predisposition to neuroblastoma results from a regulatory polymorphism that promotes the adrenergic cell state.
Nina Weichert-Leahey, Hui Shi, Ting Tao, Derek A Oldridge, Adam D Durbin, A Thomas Look

J Clin Invest· May 2023

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Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell-dependent regression of glioblastoma.
Thomas Look, Emanuele Puca, Marcel Bühler, Daniel Kirschenbaum, Roberto De Luca

Sci Transl Med· May 2023

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Targeting MET and FGFR in Relapsed or Refractory Acute Myeloid Leukemia: Preclinical and Clinical Findings, and Signal Transduction Correlates.
Evan C Chen, Helen Gandler, Isidora Tošić, Geoffrey G Fell, Ashlee Fiore, A Thomas Look

Clin Cancer Res· March 2023

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Genetic Predisposition to Neuroblastoma Results from a Regulatory Polymorphism that Promotes the Adrenergic Cell State.
Nina Weichert-Leahey, Hui Shi, Ting Tao, Derek A Oldridge, Adam D Durbin, A Thomas Look

bioRxiv· March 2023

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A lncRNA identifies enhancer element in negative feedback control of dendritic cell differentiation.
Huaming Xu, Zhijian Li, Chao-Chung Kuo, Katrin Götz, Thomas Look

Elife· March 2023

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p53 Pathway Inactivation Drives SMARCB1-deficient p53-wildtype Epithelioid Sarcoma Onset Indicating Therapeutic Vulnerability Through MDM2 Inhibition.
Felix Oppel, Senyao Shao, Sarah Gendreizig, Mark W Zimmerman, Matthias Schürmann, A Thomas Look

Mol Cancer Ther· November 2022

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Generation and validation of an IL-12 fusion protein based on a novel anti-human FAP monoclonal antibody.
Lisa Nadal, Frederik Peissert, Abdullah Elsayed, Tobias Weiss, Thomas Look

J Immunother Cancer· September 2022

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