Publications by authors named "Mary Hefford"

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Antibody light chain variable domains and their biophysically improved versions for human immunotherapy.
Dae Young Kim, Rebecca To, Hiba Kandalaft, Wen Ding, Henk van Faassen, Mary Hefford

MAbs· October 2014

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Characteristics and safety assessment of intractable proteins in genetically modified crops.
Dean F Bushey, Gary A Bannon, Bryan F Delaney, Gerson Graser, Mary Hefford

Regul Toxicol Pharmacol· July 2014

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Improved protein quality in transgenic soybean expressing a de novo synthetic protein, MB-16.
Yunfang Zhang, Johann Schernthaner, Natalie Labbé, Mary A Hefford, Jiping Zhao

Transgenic Res· June 2014

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Utility of standard pharmacopeial and nonpharmacopeial methods in distinguishing folded, unfolded, and process variant forms of interferon α-2.
John K Mark, Sophie Dionne, Terry D Cyr, Sylvie Boucher, Michel Girard, Mary Alice Hefford

J Pharm Sci· October 2012

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O-linked glycosylation leads to decreased thermal stability of interferon alpha 2b as measured by two orthogonal techniques.
Michael James Wilson Johnston, Grant Frahm, Xuguang Li, Yves Durocher, Mary Alice Hefford

Pharm Res· July 2011

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Excipient exchange in the comparison of preparations of the same biologic made by different manufacturing processes: an exploratory study with recombinant human growth hormone (rhGH).
Mike Cauchy, Mary Alice Hefford

Biologicals· November 2010

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Identification of N- and C-terminal residues involved in MAP kinase phosphatase 3 (MKP3) interdomain binding and auto-inhibition.
John K Mark, Michael J W Johnston, Mary Alice Hefford

Protein Pept Lett· October 2010

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Influence of bovine serum albumin on the secondary structure of interferon alpha 2b as determined by far UV circular dichroism spectropolarimetry.
Michael J W Johnston, Kayla Nemr, Mary A Hefford

Biologicals· March 2010

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Approach to the profiling and characterization of influenza vaccine constituents by the combined use of size-exclusion chromatography, gel electrophoresis and mass spectrometry.
Virginia Garcia-Cañas, Barry Lorbetskie, Terry D Cyr, Mary A Hefford, Sophie Smith

Biologicals· March 2010

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SARS coronavirus: unusual lability of the nucleocapsid protein.
John Mark, Xuguang Li, Terry Cyr, Sylvie Fournier, Bozena Jaentschke, Mary Alice Hefford

Biochem Biophys Res Commun· December 2008

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Glycation improves the thermostability of trypsin and chymotrypsin.
Van Thong Pham, Erin Ewing, Harvey Kaplan, Christin Choma, Mary Alice Hefford

Biotechnol Bioeng· October 2008

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Inhibition of mitogen-activated protein kinase phosphatase 3 activity by interdomain binding.
John K Mark, Rémy A Aubin, Sophie Smith, Mary Alice Hefford

J Biol Chem· October 2008

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Cytotoxic doses of ketoconazole affect expression of a subset of hepatic genes.
William L Casley, Carolina Ogrodowczyk, Louise Larocque, Bozena Jaentschke, Carole LeBlanc-Westwood, Mary Alice Hefford

J Toxicol Environ Health A· November 2007

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Over-expression and refolding of MAP kinase phosphatase 3.
John K Mark, Sophie Smith, Mary Alice Hefford

Protein Expr Purif· August 2007

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A novel cross-linked RNase A dimer with enhanced enzymatic properties.
Brigitte L Simons, Harvey Kaplan, Sylvie M Fournier, Terry Cyr, Mary Alice Hefford

Proteins· January 2007

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Enhancement of essential amino acid contents in crops by genetic engineering and protein design.
Marc Beauregard, Mary Alice Hefford

Plant Biotechnol J· September 2006

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Novel cross-linked enzyme-antibody conjugates for Western blot and ELISA.
Brigitte Simons, Harvey Kaplan, Mary Alice Hefford

J Immunol Methods· August 2006

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Covalent protein immobilization on glass surfaces: application to alkaline phosphatase.
Russell H Taylor, Sylvie M Fournier, Brigitte L Simons, Harvey Kaplan, Mary Alice Hefford

J Biotechnol· August 2005

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Thermal stability: a means to assure tertiary structure in therapeutic proteins.
Mike Cauchy, Sophie D'Aoust, Brian Dawson, Harold Rode, Mary Alice Hefford

Biologicals· September 2002

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Covalent cross-linking of proteins without chemical reagents.
Brigitte L Simons, Mary C King, Terry Cyr, Mary Alice Hefford, Harvey Kaplan

Protein Sci· June 2002

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