Publications by authors named "Mary Mathieu"

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Target arm affinities determine preclinical efficacy and safety of anti-HER2/CD3 bispecific antibody.
Karin Staflin, Christina L Zuch de Zafra, Leah K Schutt, Vanessa Clark, Fiona Zhong, Mary Mathieu

JCI Insight· April 2020

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Single cell-produced and in vitro-assembled anti-FcRH5/CD3 T-cell dependent bispecific antibodies have similar in vitro and in vivo properties.
Ayse Meric Ovacik, Ji Li, Marie Lemper, Dimitry Danilenko, Nicola Stagg, Mary Mathieu

MAbs· July 2019

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Optimizing hybrid LC-MS/MS binding conditions is critical: impact of biotransformation on quantification of trastuzumab.
Luna Liu, Keyang Xu, Jenny Li, Mauricio Maia, Mary Mathieu

Bioanalysis· November 2018

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Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye.
Devin Tesar, Jacob Luoma, Emily A Wyatt, Catherine Shi, Whitney Shatz, Mary Mathieu

MAbs· July 2018

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IgG Fc engineering to modulate antibody effector functions.
Xinhua Wang, Mary Mathieu, Randall J Brezski

Protein Cell· January 2018

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Molecular characterization of human anti-hinge antibodies derived from single-cell cloning of normal human B cells.
Tao Huang, Mary Mathieu, Sophia Lee, Xinhua Wang, Yee Seir Kee

J Biol Chem· January 2018

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An anti-CD3/anti-CLL-1 bispecific antibody for the treatment of acute myeloid leukemia.
Steven R Leong, Siddharth Sukumaran, Maria Hristopoulos, Klara Totpal, Shannon Stainton, Mary Mathieu

Blood· February 2017

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Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin.
Mark Ultsch, Bing Li, Till Maurer, Mary Mathieu, Oskar Adolfsson

Sci Rep· December 2016

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Contribution of Antibody Hydrodynamic Size to Vitreal Clearance Revealed through Rabbit Studies Using a Species-Matched Fab.
Whitney Shatz, Philip E Hass, Mary Mathieu, Hok Seon Kim, Kim Leach

Mol Pharm· September 2016

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Anti-CD20/CD3 T cell-dependent bispecific antibody for the treatment of B cell malignancies.
Liping L Sun, Diego Ellerman, Mary Mathieu, Maria Hristopoulos, Xiaocheng Chen

Sci Transl Med· May 2015

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Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells.
Teemu T Junttila, Ji Li, Jennifer Johnston, Maria Hristopoulos, Robyn Clark, Mary Mathieu

Cancer Res· October 2014

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Glycan shifting on hepatitis C virus (HCV) E2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies.
Homer Pantua, Jingyu Diao, Mark Ultsch, Meredith Hazen, Mary Mathieu

J Mol Biol· June 2013

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Inhibiting alternative pathway complement activation by targeting the factor D exosite.
Kenneth J Katschke, Ping Wu, Rajkumar Ganesan, Robert F Kelley, Mary A Mathieu

J Biol Chem· April 2012

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Multiple novel classes of APRIL-specific receptor-blocking peptides isolated by phage display.
Nathaniel C Gordon, Samantha Lien, Jeremy Johnson, Heidi J A Wallweber, Thuy Tran, Mary Mathieu

J Mol Biol· February 2010

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Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling.
Robert F Kelley, Klara Totpal, Stephanie H Lindstrom, Mary Mathieu, Karen Billeci

J Biol Chem· January 2005

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Functional expression and characterization of Schistosoma mansoni cathepsin B and its trans-activation by an endogenous asparaginyl endopeptidase.
Mohammed Sajid, James H McKerrow, Elizabeth Hansell, Mary A Mathieu, Kimberley D Lucas

Mol Biochem Parasitol· September 2003

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Substrate specificity of schistosome versus human legumain determined by P1-P3 peptide libraries.
Mary A Mathieu, Matthew Bogyo, Conor R Caffrey, Youngchool Choe, Jewok Lee

Mol Biochem Parasitol· April 2002

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