Publications by authors named "Masako Tada"

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Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity.
Chizuka Obara, Yohei Iizaka, Akari Mine, Yojiro Anzai, Masako Tada

PLoS One· December 2025

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Unveiling dynamic hepatocyte plasticity in HepaRG cells with a dual CYP reporter system.
Riku Asano, Yohei Iizaka, Makoto Kashima, Yojiro Anzai, Shinpei Yamaguchi, Masako Tada

PLoS One· November 2024

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DNMT1 can induce primary germ layer differentiation through de novo DNA methylation.
Takamasa Ito, Musashi Kubiura-Ichimaru, Fumihito Miura, Shoji Tajima, M Azim Surani, Masako Tada

Genes Cells· July 2024

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Transgenic HepaRG cells expressing CYP2D6 as an improved model of primary human hepatocytes.
Shota Okuyama, Akari Mine, Teppei Nakamura, Yusuke Ohasi, Mayuko Seto, Masako Tada

Pharmacol Res Perspect· April 2022

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DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells.
Takamasa Ito, Musashi Kubiura-Ichimaru, Yuri Murakami, Aaron B Bogutz, Louis Lefebvre, Masako Tada

PLoS One· February 2022

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Cyclic DNA remethylation following active demethylation at euchromatic regions in mouse embryonic stem cells.
Musashi Kubiura-Ichimaru, Takamasa Ito, Louis Lefebvre, Masako Tada

Chromosome Res· June 2021

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Evidence for divergence of DNA methylation maintenance and a conserved inhibitory mechanism from DNA demethylation in chickens and mammals.
Masako Tada, Ayaka Hayashi, Yumi Asano, Musashi Kubiura-Ichimaru, Takamasa Ito

Genes Genomics· March 2021

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Real-time fluorometric evaluation of hepatoblast proliferation in vivo and in vitro using the expression of CYP3A7 coding for human fetus-specific P450.
Shota Okuyama, Fumihiko Kawamura, Musashi Kubiura, Saori Tsuji, Mitsuhiko Osaki, Masako Tada

Pharmacol Res Perspect· October 2020

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A two-dimensional multiwell cell culture method for the production of CYP3A4-expressing hepatocyte-like cells from HepaRG cells.
Keiko Ooeda, Musashi Kubiura-Ichimaru, Saori Tsuji, Shota Okuyama, Mao Yamashita, Masako Tada

Pharmacol Res Perspect· October 2020

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A Cytoplasmic Form of Gaussia luciferase Provides a Highly Sensitive Test for Cytotoxicity.
Saori Tsuji, Tetsuya Ohbayashi, Kohji Yamakage, Mitsuo Oshimura, Masako Tada

PLoS One· July 2017

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Fluorometric evaluation of CYP3A4 expression using improved transgenic HepaRG cells carrying a dual-colour reporter for CYP3A4 and CYP3A7.
Takafumi Ueyama, Saori Tsuji, Takemi Sugiyama, Masako Tada

Sci Rep· June 2017

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Dual-color fluorescence imaging to monitor CYP3A4 and CYP3A7 expression in human hepatic carcinoma HepG2 and HepaRG cells.
Saori Tsuji, Fumihiko Kawamura, Musashi Kubiura, Ayaka Hayashi, Tetsuya Ohbayashi, Masako Tada

PLoS One· April 2015

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Dynamic link between histone H3 acetylation and an increase in the functional characteristics of human ESC/iPSC-derived cardiomyocytes.
Tomomi G Otsuji, Yuko Kurose, Hirofumi Suemori, Masako Tada, Norio Nakatsuji

PLoS One· March 2013

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Chromosome-wide regulation of euchromatin-specific 5mC to 5hmC conversion in mouse ES cells and female human somatic cells.
Musashi Kubiura, Masaki Okano, Hiroshi Kimura, Fumihiko Kawamura, Masako Tada

Chromosome Res· October 2012

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Hybridization of testis-derived stem cells with somatic cells and embryonic stem cells in mice.
Masanori Takehashi, Masako Tada, Mito Kanatsu-Shinohara, Hiroko Morimoto, Yasuhiro Kazuki, Takashi Tada

Biol Reprod· June 2012

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Combination of functional cardiomyocytes derived from human stem cells and a highly-efficient microelectrode array system: an ideal hybrid model assay for drug development.
Yasuyuki Asai, Masako Tada, Tomomi G Otsuji, Norio Nakatsuji

Curr Stem Cell Res Ther· September 2010

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Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs.
Tomomi G Otsuji, Itsunari Minami, Yuko Kurose, Kaori Yamauchi, Masako Tada

Stem Cell Res· May 2010

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Target chromosomes of inducible deletion by a Cre/inverted loxP system in mouse embryonic stem cells.
Masako Tada, Hiroyuki Matsumura, Yuko Kurose, Norio Nakatsuji, Takashi Tada

Chromosome Res· November 2009

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Rapid induction of large chromosomal deletions by a Cre/inverted loxP system in mouse ES Cell hybrids.
Tomomi Otsuji, Hiroyuki Matsumura, Tatsuya Suzuki, Norio Nakatsuji, Takashi Tada, Masako Tada

J Mol Biol· April 2008

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Targeted chromosome elimination from ES-somatic hybrid cells.
Hiroyuki Matsumura, Masako Tada, Tomomi Otsuji, Kentaro Yasuchika, Norio Nakatsuji, Takashi Tada

Nat Methods· January 2007

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Nuclear reprogramming of somatic nucleus hybridized with embryonic stem cells by electrofusion.
Masako Tada, Takashi Tada

Methods Mol Biol· August 2006

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Epigenetic reprogramming of somatic genomes by electrofusion with embryonic stem cells.
Masako Tada, Takashi Tada

Methods Mol Biol· July 2006

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[Molecular network of transcriptional factors controlling pluripotency of ES cells].
Takao Kuroda, Masako Tada

Seikagaku· February 2006

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Nanog expression in mouse germ cell development.
Shinpei Yamaguchi, Hironobu Kimura, Masako Tada, Norio Nakatsuji, Takashi Tada

Gene Expr Patterns· June 2005

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Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression.
Takao Kuroda, Masako Tada, Hiroshi Kubota, Hironobu Kimura, Shin-ya Hatano, Takashi Tada

Mol Cell Biol· March 2005

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