Publications by authors named "Massimo Spada"

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Isolation and phenotype analysis of tissue-resident lymphocytes from mouse colon.
Alessia Fiore, Michela Tozzi, Paola Rinzo, Daniele Macchia, Massimo Spada

Methods Cell Biol· October 2025

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Decitabine co-operates with the IL-33/ST2 axis modifying the tumor microenvironment and improving the response to PD-1 blockade in melanoma.
Francesco Noto, Jacopo Mancini, Adriana Rosa Gambardella, Christina Curcio, Adele De Ninno, Massimo Spada

J Exp Clin Cancer Res· May 2025

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E. Coli cytotoxic necrotizing factor-1 promotes colorectal carcinogenesis by causing oxidative stress, DNA damage and intestinal permeability alteration.
Michela Tozzi, Alessia Fiore, Sara Travaglione, Francesca Marcon, Gabriella Rainaldi, Massimo Spada, Francesca Spadaro

J Exp Clin Cancer Res· January 2025

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NK cells-derived extracellular vesicles potency in the B cell lymphoma biotherapy.
Serena Cecchetti, Cristina Federici, Rossella Canese, Egidio Iorio, Veronica Huber, Massimo Spada

Front Immunol· December 2024

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Author Correction: Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B.
Martina Musella, Andrea Guarracino, Nicoletta Manduca, Claudia Galassi, Eliana Ruggiero, Massimo Spada

Nat Immunol· November 2024

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Anti-Tumor Immunity to Patient-Derived Breast Cancer Cells by Vaccination with Interferon-Alpha-Conditioned Dendritic Cells (IFN-DC).
Caterina Lapenta, Stefano Maria Santini, Celeste Antonacci, Simona Donati, Serena Cecchetti, Massimo Spada

Vaccines (Basel)· September 2024

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HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks.
Matteo Cassandri, Antonella Porrazzo, Silvia Pomella, Beatrice Noce, Clemens Zwergel, Massimo Spada

Cell Death Discov· August 2024

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Hydrogen-Rich Alkaline Water Supplementation Restores a Healthy State and Redox Balance in HO-Treated Mice.
Davide Mizzoni, Mariantonia Logozzi, Rossella Di Raimo, Massimo Spada, Stefano Fais

Int J Mol Sci· June 2024

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MiR126-targeted-nanoparticles combined with PI3K/AKT inhibitor as a new strategy to overcome melanoma resistance.
Maria Beatrice Arasi, Gabriele De Luca, Laura Chronopoulou, Francesca Pedini, Eleonora Petrucci, Massimo Spada

Mol Ther· January 2024

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SARS-CoV-2-Specific CD8 T-Cells in Blood but Not in the Lungs of Vaccinated K18-hACE2 Mice after Infection.
Flavia Ferrantelli, Francesco Manfredi, Chiara Chiozzini, Patrizia Leone, Katherina Pugliese, Massimo Spada

Vaccines (Basel)· August 2023

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Antiviral effect of SARS-CoV-2 N-specific CD8 T cells induced in lungs by engineered extracellular vesicles.
Francesco Manfredi, Chiara Chiozzini, Flavia Ferrantelli, Patrizia Leone, Katherina Pugliese, Massimo Spada

NPJ Vaccines· June 2023

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Oral Treatment with Plant-Derived Exosomes Restores Redox Balance in HO-Treated Mice.
Rossella Di Raimo, Davide Mizzoni, Massimo Spada, Vincenza Dolo, Stefano Fais

Antioxidants (Basel)· May 2023

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Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B.
Martina Musella, Andrea Guarracino, Nicoletta Manduca, Claudia Galassi, Eliana Ruggiero, Massimo Spada

Nat Immunol· September 2022

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An organoid model of colorectal circulating tumor cells with stem cell features, hybrid EMT state and distinctive therapy response profile.
Maria Laura De Angelis, Federica Francescangeli, Chiara Nicolazzo, Michele Signore, Alessandro Giuliani, Massimo Spada

J Exp Clin Cancer Res· March 2022

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Strong SARS-CoV-2 N-Specific CD8 T Immunity Induced by Engineered Extracellular Vesicles Associates with Protection from Lethal Infection in Mice.
Flavia Ferrantelli, Chiara Chiozzini, Francesco Manfredi, Patrizia Leone, Massimo Spada

Viruses· February 2022

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antiaging effects of alkaline water supplementation.
Mariantonia Logozzi, Davide Mizzoni, Rossella Di Raimo, Mauro Andreotti, Daniele Macchia, Massimo Spada

J Enzyme Inhib Med Chem· December 2020

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Beneficial Effects of Fermented Papaya Preparation (FPP) Supplementation on Redox Balance and Aging in a Mouse Model.
Mariantonia Logozzi, Rossella Di Raimo, Davide Mizzoni, Mauro Andreotti, Massimo Spada

Antioxidants (Basel)· February 2020

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Inflammatory cytokines associated with cancer growth induce mitochondria and cytoskeleton alterations in cardiomyocytes.
Maria Buoncervello, Sonia Maccari, Barbara Ascione, Lucrezia Gambardella, Matteo Marconi, Massimo Spada

J Cell Physiol· November 2019

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Lenalidomide improves the therapeutic effect of an interferon-α-dendritic cell-based lymphoma vaccine.
Caterina Lapenta, Simona Donati, Francesca Spadaro, Laura Lattanzi, Francesca Urbani, Massimo Spada

Cancer Immunol Immunother· November 2019

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Joint action of miR-126 and MAPK/PI3K inhibitors against metastatic melanoma.
Francesca Pedini, Gabriele De Luca, Federica Felicetti, Rossella Puglisi, Alessandra Boe, Massimo Spada

Mol Oncol· September 2019

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Clinical and Antitumor Immune Responses in Relapsed/Refractory Follicular Lymphoma Patients after Intranodal Injections of IFNα-Dendritic Cells and Rituximab: a Phase I Clinical Trial.
M Christina Cox, Luciano Castiello, Mauro Mattei, Laura Santodonato, Giuseppina D'Agostino, Francesca Spadaro, Massimo Spada

Clin Cancer Res· September 2019

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Autoantibodies Specific to ERα are Involved in Tamoxifen Resistance in Hormone Receptor Positive Breast Cancer.
Angela Maselli, Stefania Parlato, Rossella Puglisi, Carla Raggi, Massimo Spada

Cells· July 2019

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A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors.
Isabella Orienti, Federica Francescangeli, Maria Laura De Angelis, Katia Fecchi, Lucilla Bongiorno-Borbone, Massimo Spada

Cell Death Dis· July 2019

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Oral Administration of Fermented Papaya (FPP) Controls the Growth of a Murine Melanoma through the In Vivo Induction of a Natural Antioxidant Response.
Mariantonia Logozzi, Davide Mizzoni, Rossella Di Raimo, Daniele Macchia, Massimo Spada

Cancers (Basel)· January 2019

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IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils.
Valeria Lucarini, Giovanna Ziccheddu, Iole Macchia, Valentina La Sorsa, Francesca Peschiaroli, Massimo Spada

Oncoimmunology· April 2017

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