Publications by authors named "Matteo Cassandri"

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Inhibition of bromodomain and extra-terminal motif (BET) proteins in pediatric sarcoma: A systematic review of in vitro and in vivo studies.
Erika Ferraro, Elisa Macrì, Clemens Zwergel, Chiara Lambona, Giovanni Barillari, Matteo Cassandri

Drug Discov Today· December 2025

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Neddylation inhibition induces DNA double-strand breaks, hampering tumor growth in vivo, and promotes radiosensitivity in PAX3-FOXO1 rhabdomyosarcoma.
Francesca Antonella Aiello, Lucrezia D'Archivio, Marika Attili, Erika Ferraro, Elisa Macrì, Matteo Cassandri

Cell Death Discov· November 2025

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The HIV Protease Inhibitor Ritonavir Reverts the Mesenchymal Phenotype Induced by Inflammatory Cytokines in Normal and Tumor Oral Keratinocytes to an Epithelial One, Increasing the Radiosensitivity of Tumor Oral Keratinocytes.
Silvia Pomella, Lucrezia D'Archivio, Matteo Cassandri, Francesca Antonella Aiello, Ombretta Melaiu

Cancers (Basel)· July 2025

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Age-linked DNA methylation and gene expression patterns in parameningeal head and neck alveolar rhabdomyosarcoma reveal CDK9 as a promising therapeutic target.
Sara Patrizi, Silvia Vallese, Sabina Barresi, Matteo Cassandri, Isabella Giovannoni

Pharmacol Res· June 2025

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Synthetic inhibition of SREBP2 and the mevalonate pathway blocks rhabdomyosarcoma tumor growth in vitro and in vivo and promotes chemosensitization.
Silvia Codenotti, Michela Asperti, Maura Poli, Luisa Lorenzi, Alberto Pietrantoni, Matteo Cassandri

Mol Metab· February 2025

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Deciphering the Transcriptional Metabolic Profile of Adipose-Derived Stem Cells During Osteogenic Differentiation and Epigenetic Drug Treatment.
Giulia Gerini, Alice Traversa, Fabrizio Cece, Matteo Cassandri, Paola Pontecorvi

Cells· January 2025

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Tumor-derived G-CSF induces an immunosuppressive microenvironment in an osteosarcoma model, reducing response to CAR.GD2 T-cells.
Michele Pezzella, Concetta Quintarelli, Maria C Quadraccia, Andrea Sarcinelli, Simona Manni, Matteo Cassandri

J Hematol Oncol· December 2024

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HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks.
Matteo Cassandri, Antonella Porrazzo, Silvia Pomella, Beatrice Noce, Clemens Zwergel

Cell Death Discov· August 2024

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Antitumour effects of SFX-01 molecule in combination with ionizing radiation in preclinical and in vivo models of rhabdomyosarcoma.
Simona Camero, Luisa Milazzo, Francesca Vulcano, Federica Ceccarelli, Paola Pontecorvi, Matteo Cassandri

BMC Cancer· July 2024

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DNA repair in tumor radioresistance: insights from fruit flies genetics.
Antonella Porrazzo, Matteo Cassandri, Andrea D'Alessandro, Patrizia Morciano, Rossella Rota

Cell Oncol (Dordr)· June 2024

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Statin-Sensitive Akt1/Src/Caveolin-1 Signaling Enhances Oxidative Stress Resistance in Rhabdomyosarcoma.
Silvia Codenotti, Leonardo Sandrini, Delia Mandracchia, Luisa Lorenzi, Giovanni Corsetti, Matteo Cassandri

Cancers (Basel)· February 2024

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MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57 targeting.
Silvia Pomella, Matteo Cassandri, Lucrezia D'Archivio, Antonella Porrazzo, Cristina Cossetti

Nat Commun· December 2023

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Heat Shock Proteins: Important Helpers for the Development, Maintenance and Regeneration of Skeletal Muscles.
Silvia Pomella, Matteo Cassandri, Francesco Antoniani, Samuele Crotti, Laura Mediani

Muscles· April 2023

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ZFP750 affects the cutaneous barrier through regulating lipid metabolism.
Alessio Butera, Massimiliano Agostini, Matteo Cassandri, Francesca De Nicola, Maurizio Fanciulli

Sci Adv· April 2023

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Spermine oxidase induces DNA damage and sensitizes fusion negative rhabdomyosarcoma cells to irradiation.
Clara Perrone, Silvia Pomella, Matteo Cassandri, Michele Pezzella, Stefano Giuliani

Front Cell Dev Biol· January 2023

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DNA Damage Response Gene Signature as Potential Treatment Markers for Oral Squamous Cell Carcinoma.
Silvia Pomella, Matteo Cassandri, Ombretta Melaiu, Francesco Marampon, Marco Gargari

Int J Mol Sci· January 2023

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The botanical drug PBI-05204, a supercritical CO extract of , sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy and .
Sara Vaccaro, Alessandra Rossetti, Antonella Porrazzo, Simona Camero, Matteo Cassandri

Front Pharmacol· December 2022

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Translational Implications for Radiosensitizing Strategies in Rhabdomyosarcoma.
Silvia Pomella, Antonella Porrazzo, Matteo Cassandri, Simona Camero, Silvia Codenotti

Int J Mol Sci· October 2022

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Hyperactive Akt1 Signaling Increases Tumor Progression and DNA Repair in Embryonal Rhabdomyosarcoma RD Line and Confers Susceptibility to Glycolysis and Mevalonate Pathway Inhibitors.
Silvia Codenotti, Daniela Zizioli, Luca Mignani, Sara Rezzola, Giovanna Tabellini, Matteo Cassandri

Cells· September 2022

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Radioresistance in rhabdomyosarcomas: Much more than a question of dose.
Simona Camero, Matteo Cassandri, Silvia Pomella, Luisa Milazzo, Francesca Vulcano

Front Oncol· September 2022

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Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models.
Martina Menna, Francesco Fiorentino, Biagina Marrocco, Alessia Lucidi, Stefano Tomassi, Matteo Cassandri

Eur J Med Chem· July 2022

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MET Inhibition Sensitizes Rhabdomyosarcoma Cells to NOTCH Signaling Suppression.
Clara Perrone, Silvia Pomella, Matteo Cassandri, Michele Pezzella, Giuseppe Maria Milano

Front Oncol· April 2022

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New Insights on the Nuclear Functions and Targeting of FAK in Cancer.
Silvia Pomella, Matteo Cassandri, Maria Rita Braghini, Francesco Marampon, Anna Alisi

Int J Mol Sci· February 2022

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MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells.
Matteo Cassandri, Silvia Pomella, Alessandra Rossetti, Francesco Petragnano, Luisa Milazzo

Int J Mol Sci· October 2021

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DNMT3A and DNMT3B Targeting as an Effective Radiosensitizing Strategy in Embryonal Rhabdomyosarcoma.
Simona Camero, Giulia Vitali, Paola Pontecorvi, Simona Ceccarelli, Eleni Anastasiadou, Matteo Cassandri

Cells· October 2021

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