Publications by authors named "Mathew Garnett"

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A next-generation dual guide CRISPR system for genetic interaction library screening.
Thomas Burgold, Emre Karakoc, Emanuel Gonçalves, Inigo Barrio-Hernandez, Lisa Dwane, Mathew J Garnett

Nat Commun· December 2025

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Large-scale drug sensitivity, gene dependency, and proteogenomic analyses of telomere maintenance mechanisms in cancer cells.
Yangxiu Wu, Zhaoxiang Cai, Dale Cross, Jane R Noble, Kelsy Prest, Mathew J Garnett

Nat Commun· December 2025

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Knowledge of idiopathic normal pressure hydrocephalus among healthcare professionals.
Rocío Fernández-Méndez, Toby Meek, Benjamin Dias-Dougan, Lisa Healy, Indu Lawes, Mathew R Garnett

Sci Rep· August 2025

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Interferon-Inducible ADAR1 p150 Is Essential for the Survival of Oral Squamous Cell Carcinoma.
Pei San Yee, Annie Wai Yeeng Chai, Shi Mun Yee, Shiyin Ooi, Yee Hua Tan, Mathew J Garnett

Mol Carcinog· June 2025

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Author Correction: Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning.
Zhaoxiang Cai, Sofia Apolinário, Ana R Baião, Clare Pacini, Miguel D Sousa, Mathew J Garnett

Nat Commun· February 2025

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Benchmark Software and Data for Evaluating CRISPR-Cas9 Experimental Pipelines Through the Assessment of a Calibration Screen.
Raffaele M Iannuzzi, Ichcha Manipur, Clare Pacini, Fiona M Behan, Mario R Guarracino, Mathew J Garnett

CRISPR J· December 2024

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High TNF and NF-κB Pathway Dependency Are Associated with AZD5582 Sensitivity in OSCC via CASP8-Dependent Apoptosis.
Annie Wai Yeeng Chai, Yee Hua Tan, Shiyin Ooi, Pei San Yee, Shi Mun Yee, Mathew J Garnett

Cancer Res Commun· November 2024

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Base editing screens define the genetic landscape of cancer drug resistance mechanisms.
Matthew A Coelho, Magdalena E Strauss, Alex Watterson, Sarah Cooper, Shriram Bhosle, Mathew J Garnett

Nat Genet· November 2024

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Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning.
Zhaoxiang Cai, Sofia Apolinário, Ana R Baião, Clare Pacini, Miguel D Sousa, Mathew J Garnett

Nat Commun· November 2024

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Cancer drug-tolerant persister cells: from biological questions to clinical opportunities.
Mariangela Russo, Mengnuo Chen, Elisa Mariella, Haoning Peng, Sumaiyah K Rehman, Mathew J Garnett

Nat Rev Cancer· October 2024

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Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells.
Gabriele Picco, Yanhua Rao, Angham Al Saedi, Yang Lee, Sara F Vieira, Mathew J Garnett

Cancer Discov· August 2024

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A pan-cancer screen identifies drug combination benefit in cancer cell lines at the individual and population level.
Daniel J Vis, Patricia Jaaks, Nanne Aben, Elizabeth A Coker, Syd Barthorpe, Mathew J Garnett

Cell Rep Med· August 2024

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Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations.
Azadeh C Bashi, Elizabeth A Coker, Krishna C Bulusu, Patricia Jaaks, Claire Crafter, Mathew J Garnett

Cancer Discov· May 2024

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Establishment and Characterization of an Epstein-Barr Virus-positive Cell Line from a Non-keratinizing Differentiated Primary Nasopharyngeal Carcinoma.
Annie Wai Yeeng Chai, Shi Mun Yee, Hui Mei Lee, Norazlin Abdul Aziz, Pei San Yee, Mathew J Garnett

Cancer Res Commun· March 2024

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A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization.
Clare Pacini, Emma Duncan, Emanuel Gonçalves, James Gilbert, Shriram Bhosle, Mathew J Garnett

Cancer Cell· February 2024

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Tissue Organoid Cultures Metabolize Dietary Carcinogens Proficiently and Are Effective Models for DNA Adduct Formation.
Angela L Caipa Garcia, Jill E Kucab, Halh Al-Serori, Rebekah S S Beck, Madjda Bellamri, Mathew J Garnett

Chem Res Toxicol· February 2024

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Haplotype-specific assembly of shattered chromosomes in esophageal adenocarcinomas.
Jannat Ijaz, Edward Harry, Keiran Raine, Andrew Menzies, Kathryn Beal, Mathew J Garnett

Cell Genom· February 2024

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Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs models of mesothelioma.
Joanna Obacz, Jose Antonio Valer, Reshma Nibhani, Taylor S Adams, Jonas C Schupp, Mathew J Garnett

Eur Respir J· January 2024

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scSNV-seq: high-throughput phenotyping of single nucleotide variants by coupled single-cell genotyping and transcriptomics.
Sarah E Cooper, Matthew A Coelho, Magdalena E Strauss, Aleksander M Gontarczyk, Qianxin Wu, Mathew J Garnett

Genome Biol· January 2024

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Highlights from the 1st European cancer dependency map symposium and workshop.
Lucia Trastulla, Aurora Savino, Pedro Beltrao, Isidro Cortés Ciriano, Peter Fenici, Mathew J Garnett

FEBS Lett· August 2023

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A landscape of response to drug combinations in non-small cell lung cancer.
Nishanth Ulhas Nair, Patricia Greninger, Xiaohu Zhang, Adam A Friedman, Arnaud Amzallag, Mathew J Garnett

Nat Commun· June 2023

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RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status.
Coralie Dorard, Claire Madry, Olivier Buhard, Stefanie Toifl, Sebastian Didusch, Mathew J Garnett

Oncogene· May 2023

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Base editing screens map mutations affecting interferon-γ signaling in cancer.
Matthew A Coelho, Sarah Cooper, Magdalena E Strauss, Emre Karakoc, Shriram Bhosle, Mathew J Garnett

Cancer Cell· February 2023

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Metabolic Activation of Benzo[]pyrene by Human Tissue Organoid Cultures.
Angela L Caipa Garcia, Jill E Kucab, Halh Al-Serori, Rebekah S S Beck, Franziska Fischer, Mathew Garnett

Int J Mol Sci· December 2022

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AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors.
Shanade Dunn, Cath Eberlein, Jason Yu, Albert Gris-Oliver, Swee Hoe Ong, Mathew J Garnett

Oncogene· November 2022

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