Publications by authors named "Mathias Haag"

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Klebsiella pneumoniae contributes to altered cytotoxicity of thiopurines in vitro: Possible implications of biotransformation and bacterial metabolism.
Martina Franzin, Cristina Lagatolla, Sofia Sindici Forgiarini, Mathias Haag, Sylvia Karin Neef

Br J Pharmacol· September 2025

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Circulating metabolite signatures indicate differential gut-liver crosstalk in lean and obese MASLD.
Mathias Haag, Stefan Winter, Aurino M Kemas, Julia Tevini, Alexandra Feldman

JCI Insight· April 2025

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The liver proteome of individuals with a natural UGT2B17 complete deficiency.
Michèle Rouleau, Matthias Schwab, Kathrin Klein, Roman Tremmel, Mathias Haag

Sci Rep· February 2025

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First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure.
Stefan Zwirner, Anan A Abu Rmilah, Sabrina Klotz, Bent Pfaffenroth, Philip Kloevekorn, Mathias Haag

Cell· March 2024

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Circulating Biomarkers Instead of Genotyping to Establish Metabolizer Phenotypes.
Roman Tremmel, Ute Hofmann, Mathias Haag, Elke Schaeffeler, Matthias Schwab

Annu Rev Pharmacol Toxicol· January 2024

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Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation.
Anne T Nies, Jörg König, Patrick Leuthold, Katja Damme, Stefan Winter, Mathias Haag

Pharmacol Res· October 2023

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Performance comparison of narrow-bore and capillary liquid-chromatography for non-targeted metabolomics profiling by HILIC-QTOF-MS.
Sylvia K Neef, Ute Hofmann, Thomas E Mürdter, Matthias Schwab, Mathias Haag

Talanta· August 2023

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Evaluation of the drug-drug interaction potential of the novel hepatitis B and D virus entry inhibitor bulevirtide at OATP1B in healthy volunteers.
Vanessa Zhu, Jürgen Burhenne, Johanna Weiss, Mathias Haag, Ute Hofmann

Front Pharmacol· April 2023

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Safety and efficacy of bulevirtide in combination with tenofovir disoproxil fumarate in patients with hepatitis B virus and hepatitis D virus coinfection (MYR202): a multicentre, randomised, parallel-group, open-label, phase 2 trial.
Heiner Wedemeyer, Katrin Schöneweis, Pavel Bogomolov, Antje Blank, Natalia Voronkova, Mathias Haag

Lancet Infect Dis· January 2023

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Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide-An Exploratory Phase I Clinical Trial.
Felicitas Stoll, Andrea Seidel-Glätzer, Ina Burghaus, Oliver Göring, Max Sauter, Mathias Haag

Int J Mol Sci· December 2022

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Molybdenum Cofactor Catabolism Unravels the Physiological Role of the Drug Metabolizing Enzyme Thiopurine S-Methyltransferase.
Julika Pristup, Elke Schaeffeler, Sita Arjune, Ute Hofmann, Jose Angel Santamaria-Araujo, Mathias Haag

Clin Pharmacol Ther· October 2022

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Untargeted stable isotope-resolved metabolomics to assess the effect of PI3Kβ inhibition on metabolic pathway activities in a PTEN null breast cancer cell line.
Marcel Lackner, Sylvia K Neef, Stefan Winter, Sandra Beer-Hammer, Bernd Nürnberg, Mathias Haag

Front Mol Biosci· October 2022

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CD147 a direct target of miR-146a supports energy metabolism and promotes tumor growth in ALK+ ALCL.
Ivonne-Aidee Montes-Mojarro, Julia Steinhilber, Christoph M Griessinger, Achim Rau, Ann-Kathrin Gersmann, Mathias Haag

Leukemia· August 2022

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Hepatic Expression of the Na-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation.
Roman Tremmel, Anne T Nies, Barbara A C van Eijck, Niklas Handin, Mathias Haag

Int J Mol Sci· July 2022

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Nicotinamide-N-methyltransferase is a promising metabolic drug target for primary and metastatic clear cell renal cell carcinoma.
Anna Reustle, Lena-Sophie Menig, Patrick Leuthold, Ute Hofmann, Viktoria Stühler, Mathias Haag

Clin Transl Med· June 2022

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Metabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS.
Sylvia K Neef, Nicole Janssen, Stefan Winter, Svenja K Wallisch, Ute Hofmann, Mathias Haag

Metabolites· December 2020

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Optimized protocol for metabolomic and lipidomic profiling in formalin-fixed paraffin-embedded kidney tissue by LC-MS.
Sylvia K Neef, Stefan Winter, Ute Hofmann, Thomas E Mürdter, Elke Schaeffeler, Mathias Haag

Anal Chim Acta· October 2020

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Integrative -omics and HLA-ligandomics analysis to identify novel drug targets for ccRCC immunotherapy.
Anna Reustle, Moreno Di Marco, Carolin Meyerhoff, Annika Nelde, Juliane S Walz, Mathias Haag

Genome Med· March 2020

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Simultaneous Extraction of RNA and Metabolites from Single Kidney Tissue Specimens for Combined Transcriptomic and Metabolomic Profiling.
Patrick Leuthold, Matthias Schwab, Ute Hofmann, Stefan Winter, Steffen Rausch, Mathias Haag

J Proteome Res· September 2018

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Systemic regulation of bilirubin homeostasis: Potential benefits of hyperbilirubinemia.
Ryoichi Fujiwara, Mathias Haag, Elke Schaeffeler, Anne T Nies, Ulrich M Zanger

Hepatology· April 2018

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Comprehensive Metabolomic and Lipidomic Profiling of Human Kidney Tissue: A Platform Comparison.
Patrick Leuthold, Elke Schaeffeler, Stefan Winter, Florian Büttner, Ute Hofmann, Mathias Haag

J Proteome Res· February 2017

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Treatment of chronic hepatitis D with the entry inhibitor myrcludex B: First results of a phase Ib/IIa study.
Pavel Bogomolov, Alexander Alexandrov, Natalia Voronkova, Maria Macievich, Ksenia Kokina, Mathias Haag

J Hepatol· September 2016

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First-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex B.
Antje Blank, Christoph Markert, Nicolas Hohmann, Alexandra Carls, Gerd Mikus, Mathias Haag

J Hepatol· September 2016

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Interaction of MDM33 with mitochondrial inner membrane homeostasis pathways in yeast.
Till Klecker, Megan Wemmer, Mathias Haag, Alfons Weig, Stefan Böckler

Sci Rep· December 2015

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Quantitative bile acid profiling by liquid chromatography quadrupole time-of-flight mass spectrometry: monitoring hepatitis B therapy by a novel Na(+)-taurocholate cotransporting polypeptide inhibitor.
Mathias Haag, Ute Hofmann, Thomas E Mürdter, Georg Heinkele, Patrick Leuthold

Anal Bioanal Chem· September 2015

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