Publications by authors named "Mathias Lichtenheld"

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The Fallacy of Teaching and the Illusion of Learning: Improving Articulation of Basic Science in the Medical School Curriculum.
Maria H van Zuilen, Jonathan S England, Daniel A Sussman, Amar R Deshpande, Alex J Mechaber, Mathias G Lichtenheld

Med Sci Educ· December 2020

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Perforin-2 Breaches the Envelope of Phagocytosed Bacteria Allowing Antimicrobial Effectors Access to Intracellular Targets.
Fangfang Bai, Ryan M McCormack, Suzanne Hower, Gregory V Plano, Mathias G Lichtenheld

J Immunol· November 2018

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Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria.
Ryan M McCormack, Lesley R de Armas, Motoaki Shiratsuchi, Desiree G Fiorentino, Melissa L Olsson, Mathias G Lichtenheld

Elife· September 2015

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Understanding the biology of ex vivo-expanded CD8 T cells for adoptive cell therapy: role of CD62L.
C Marcela Díaz-Montero, Abdel-Aziz Zidan, Maria F Pallin, Vasileios Anagnostopoulos, Mohamed L Salem, Mathias G Lichtenheld

Immunol Res· December 2013

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HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases.
Jung-Hyun Lee, Sebastian Wittki, Tanja Bräu, Florian S Dreyer, Kirsten Krätzel, Mathias Lichtenheld

Mol Cell· February 2013

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Synergy of brief activation of CD8 T-cells in the presence of IL-12 and adoptive transfer into lymphopenic hosts promotes tumor clearance and anti-tumor memory.
C Marcela Díaz-Montero, Osama Naga, Abdel-Aziz A Zidan, Mohamed L Salem, Maria Pallin, Mathias G Lichtenheld

Am J Cancer Res· August 2011

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Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cells.
Anita Parmigiani, Maria F Pallin, Helena Schmidtmayerova, Mathias G Lichtenheld, Savita Pahwa

Hum Immunol· February 2011

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The transcriptional control of the perforin locus.
Matthew E Pipkin, Anjana Rao, Mathias G Lichtenheld

Immunol Rev· May 2010

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Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells.
Matthew E Pipkin, Jilian A Sacks, Fernando Cruz-Guilloty, Mathias G Lichtenheld, Michael J Bevan

Immunity· January 2010

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Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs.
Fernando Cruz-Guilloty, Matthew E Pipkin, Ivana M Djuretic, Ditsa Levanon, Joseph Lotem, Mathias G Lichtenheld

J Exp Med· January 2009

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HIV Nef enhances Tat-mediated viral transcription through a hnRNP-K-nucleated signaling complex.
Dietlinde Wolf, Vanessa Witte, Pat Clark, Katja Blume, Mathias G Lichtenheld

Cell Host Microbe· October 2008

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IL-21 augments natural killer effector functions in chronically HIV-infected individuals.
Natasa Strbo, Lesley de Armas, Huanliang Liu, Michael A Kolber, Mathias Lichtenheld

AIDS· August 2008

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Differential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV).
Lesley White, Subramaniam Krishnan, Natasa Strbo, Huanliang Liu, Michael A Kolber, Mathias G Lichtenheld

Blood· May 2007

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Murine neonatal CD4+ cells are poised for rapid Th2 effector-like function.
Shawn Rose, Mathias Lichtenheld, Monica R Foote, Becky Adkins

J Immunol· March 2007

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Chromosome transfer activates and delineates a locus control region for perforin.
Matthew E Pipkin, Belma Ljutic, Fernando Cruz-Guilloty, Marcela Nouzova, Anjana Rao, Mathias G Lichtenheld

Immunity· January 2007

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A reliable method to display authentic DNase I hypersensitive sites at long-ranges in single-copy genes from large genomes.
Matthew E Pipkin, Mathias G Lichtenheld

Nucleic Acids Res· March 2006

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Characterization of a R115777-resistant human multiple myeloma cell line with cross-resistance to PS-341.
Robert Buzzeo, Steven Enkemann, Rama Nimmanapalli, Melissa Alsina, Mathias G Lichtenheld

Clin Cancer Res· August 2005

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Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells.
Kuichun Zhu, Elvira Gerbino, Darrin M Beaupre, Paul A Mackley, Carlos Muro-Cacho, Mathias G Lichtenheld

Blood· June 2005

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R115777 induces Ras-independent apoptosis of myeloma cells via multiple intrinsic pathways.
Darrin M Beaupre, Enrique Cepero, Esther A Obeng, Lawrence H Boise, Mathias G Lichtenheld

Mol Cancer Ther· February 2004

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Farnesyl transferase inhibitors enhance death receptor signals and induce apoptosis in multiple myeloma cells.
Darrin M Beaupre, Jennifer McCafferty-Grad, Nizar J Bahlis, Lawrence H Boise, Mathias G Lichtenheld

Leuk Lymphoma· December 2003

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DNA methylation and chromatin structure regulate T cell perforin gene expression.
Qianjin Lu, Ailing Wu, Donna Ray, Chun Deng, John Attwood, Mathias Lichtenheld

J Immunol· May 2003

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A role for NF-kappa B activation in perforin expression of NK cells upon IL-2 receptor signaling.
Jun Zhou, Jin Zhang, Mathias G Lichtenheld, Gary G Meadows

J Immunol· August 2002

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