Publications by authors named "Mathias W Hackl"

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Substantial Comparability of Singlicate Versus Duplicate Analysis-A Retrospective Evaluation of Clinical Immunogenicity in a Biosimilar PK Study.
Maike Lichtenfels, Jamie Fan, Davide Guerrieri, Mathias W Hackl, Ana Villalba Izquierdo

AAPS J· December 2025

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Small molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers.
Martina Meßner, Melanie M Mandl, Mathias W Hackl, Till Reinhardt, Maximilian A Ardelt

Sci Rep· May 2021

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A tailored phosphoaspartate probe unravels CprR as a response regulator in interkingdom signaling.
Patrick W A Allihn, Mathias W Hackl, Christina Ludwig, Stephan M Hacker, Stephan A Sieber

Chem Sci· February 2021

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Comparative Target Analysis of Chlorinated Biphenyl Antimicrobials Highlights MenG as a Molecular Target of Triclocarban.
Robert Macsics, Mathias W Hackl, Christian Fetzer, Dietrich Mostert, Jennifer Bender

Appl Environ Microbiol· August 2020

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Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms.
Philipp Le, Elena Kunold, Robert Macsics, Katharina Rox, Megan C Jennings, Mathias W Hackl

Nat Chem· February 2020

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In Vesiculo Synthesis of Peptide Membrane Precursors for Autonomous Vesicle Growth.
Kilian Vogele, Thomas Frank, Lukas Gasser, Marisa A Goetzfried, Mathias W Hackl

J Vis Exp· June 2019

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Towards synthetic cells using peptide-based reaction compartments.
Kilian Vogele, Thomas Frank, Lukas Gasser, Marisa A Goetzfried, Mathias W Hackl

Nat Commun· September 2018

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Design and synthesis of tailored human caseinolytic protease P inhibitors.
Thomas F Gronauer, Melanie M Mandl, Markus Lakemeyer, Mathias W Hackl, Martina Meßner

Chem Commun (Camb)· August 2018

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Reversible Inhibitors Arrest ClpP in a Defined Conformational State that Can Be Revoked by ClpX Association.
Axel Pahl, Markus Lakemeyer, Marie-Theres Vielberg, Mathias W Hackl, Jan Vomacka

Angew Chem Int Ed Engl· December 2015

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Phenyl Esters Are Potent Inhibitors of Caseinolytic Protease P and Reveal a Stereogenic Switch for Deoligomerization.
Mathias W Hackl, Markus Lakemeyer, Maria Dahmen, Manuel Glaser, Axel Pahl

J Am Chem Soc· July 2015

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A mass spectrometry platform for a streamlined investigation of proteasome integrity, posttranslational modifications, and inhibitor binding.
Malte Gersch, Mathias W Hackl, Christian Dubiella, Alexander Dobrinevski, Michael Groll

Chem Biol· March 2015

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