Publications by authors named "Mathilde Chaineau"

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Transcriptome-based screening in TARDBP/TDP-43 knock-in motor neurons identifies the NEDD8-activating enzyme inhibitor MLN4924.
Sarah Lépine, Gilles Maussion, Alexandria Schneider, Angela Nauleau-Javaudin, María José Castellanos-Montiel, Mathilde Chaineau

Sci Rep· August 2025

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Early nuclear phenotypes and reactive transformation in human iPSC-derived astrocytes from ALS patients with SOD1 mutations.
Vincent Soubannier, Mathilde Chaineau, Lale Gursu, Sarah Lépine, David Kalaydjian

Glia· November 2024

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Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons.
Sarah Lépine, Angela Nauleau-Javaudin, Eric Deneault, Carol X-Q Chen, Narges Abdian, Mathilde Chaineau

iScience· March 2024

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An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids.
María José Castellanos-Montiel, Mathilde Chaineau, Anna Kristyna Franco-Flores, Ghazal Haghi, Dulce Carrillo-Valenzuela

Cells· February 2023

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A streamlined CRISPR workflow to introduce mutations and generate isogenic iPSCs for modeling amyotrophic lateral sclerosis.
Eric Deneault, Mathilde Chaineau, Michael Nicouleau, Maria José Castellanos Montiel, Anna Kristyna Franco Flores

Methods· July 2022

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Rapid Generation of Ventral Spinal Cord-like Astrocytes from Human iPSCs for Modeling Non-Cell Autonomous Mechanisms of Lower Motor Neuron Disease.
Vincent Soubannier, Mathilde Chaineau, Lale Gursu, Ghazal Haghi, Anna Kristyna Franco Flores

Cells· January 2022

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Target 2035 - update on the quest for a probe for every protein.
Susanne Müller, Suzanne Ackloo, Arij Al Chawaf, Bissan Al-Lazikani, Albert Antolin, Mathilde Chaineau

RSC Med Chem· January 2022

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An Arf/Rab cascade controls the growth and invasiveness of glioblastoma.
Gopinath Kulasekaran, Mathilde Chaineau, Valerio Emilio Crescenzo Piscopo, Federica Verginelli, Maryam Fotouhi

J Cell Biol· February 2021

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The Neglected Genes of ALS: Cytoskeletal Dynamics Impact Synaptic Degeneration in ALS.
María José Castellanos-Montiel, Mathilde Chaineau, Thomas M Durcan

Front Cell Neurosci· November 2020

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Characterization of human iPSC-derived astrocytes with potential for disease modeling and drug discovery.
Vincent Soubannier, Gilles Maussion, Mathilde Chaineau, Veronika Sigutova, Guy Rouleau

Neurosci Lett· July 2020

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TNF receptor-associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation.
Sabrina Semmler, Myriam Gagné, Pranav Garg, Sarah R Pickles, Charlotte Baudouin, Mathilde Chaineau

J Biol Chem· March 2020

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Open Science Meets Stem Cells: A New Drug Discovery Approach for Neurodegenerative Disorders.
Chanshuai Han, Mathilde Chaineau, Carol X-Q Chen, Lenore K Beitel, Thomas M Durcan

Front Neurosci· February 2018

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DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior.
Maria S Ioannou, Emily S Bell, Martine Girard, Mathilde Chaineau, Jason N R Hamlin

J Cell Biol· March 2015

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LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation.
Andrea M A Schreij, Mathilde Chaineau, Wenjing Ruan, Susan Lin, Philip A Barker

EMBO Rep· January 2015

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Rab35: GEFs, GAPs and effectors.
Mathilde Chaineau, Maria S Ioannou, Peter S McPherson

Traffic· November 2013

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Interplay between Rab35 and Arf6 controls cargo recycling to coordinate cell adhesion and migration.
Patrick D Allaire, Mohamed Seyed Sadr, Mathilde Chaineau, Emad Seyed Sadr, Sarah Konefal

J Cell Sci· February 2013

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Role of TI-VAMP and CD82 in EGFR cell-surface dynamics and signaling.
Lydia Danglot, Mathilde Chaineau, Maxime Dahan, Marie-Claude Gendron, Nicole Boggetto

J Cell Sci· March 2010

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Dynamic interaction of amphiphysin with N-WASP regulates actin assembly.
Hiroshi Yamada, Sergi Padilla-Parra, Sun-Joo Park, Toshiki Itoh, Mathilde Chaineau

J Biol Chem· December 2009

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Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking.
Mathilde Chaineau, Lydia Danglot, Thierry Galli

FEBS Lett· December 2009

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Role of HRB in clathrin-dependent endocytosis.
Mathilde Chaineau, Lydia Danglot, Véronique Proux-Gillardeaux, Thierry Galli

J Biol Chem· December 2008

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