Publications by authors named "Matthew Auton"

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Structure-resolved dynamics of type 2M von Willebrand disease.
Alexander Tischer, Laurie Moon-Tasson, Matthew Auton

J Thromb Haemost· April 2025

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The epitope of the antibody used in the REAADS VWF activity assay is quaternary.
Alexander Tischer, Laurie Moon-Tasson, Matthew Auton

Thromb J· January 2025

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Conformation-specific RNA aptamers for phenotypic distinction between normal von Willebrand factor and type 2B von Willebrand disease.
Venkata R Machha, Alexander Tischer, Laurie Moon-Tasson, Julie Tange, Annyoceli Santiago-Davis, Matthew Auton

NAR Mol Med· October 2024

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Biophysical characterization of human-cell-expressed, full-length κI O18/O8, AL-09, λ6a, and Wil immunoglobulin light chains.
Pinaki Misra, Alexander Tischer, Lindsey Lampe, Valeria Pierluissi-Ruiz, Christopher J Dick, Matthew Auton

Biochim Biophys Acta Proteins Proteom· May 2024

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A murine multiple-injury model for the study of thromboinflammation.
Taleen A MacArthur, Julie Goswami, Sergio M Navarro, Grant M Spears, Kent R Bailey, Matthew T Auton

J Trauma Acute Care Surg· February 2024

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Wedging the door open on platelet-type von Willebrand disease.
Matthew Auton, Alexander Tischer

Br J Haematol· November 2023

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Removal of the vicinal disulfide enhances the platelet-capturing function of von Willebrand factor.
Alexander Tischer, Laurie Moon-Tasson, Matthew Auton

Blood· March 2023

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Plasma thrombin generation kinetics in trauma patients across the age spectrum.
Julie Goswami, Taleen A MacArthur, Cillian R Mahony, Joseph Immermann, Michael J Ferrara, Matthew T Auton

Surg Pract Sci· September 2022

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ThANNCs for kinetically optimizing ITC.
Matthew Auton

Biophys J· June 2022

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A p.Arg127Gln variant in GPIbα LRR5 allosterically enhances affinity for VWF: a novel form of platelet-type VWD.
Loredana Bury, Emanuela Falcinelli, Haripriya Kuchi Bhotla, Anna Maria Mezzasoma, Giuseppe Guglielmini, Matthew Auton

Blood Adv· April 2022

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Gain-of-Function Variant p.Pro2555Arg of von Willebrand Factor Increases Aggregate Size through Altering Stem Dynamics.
Volker Huck, Po-Chia Chen, Emma-Ruoqi Xu, Alexander Tischer, Ulrike Klemm, Matthew Auton

Thromb Haemost· February 2022

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Biomarkers of thromboinflammation correlate to COVID-19 infection and admission status in emergency department patients.
Julie Goswami, Taleen A MacArthur, Meera Sridharan, Julie Tange, Andrew J Kirmse, Matthew T Auton

Thromb Update· December 2021

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Neutrophil Extracellular Trap Formation and Syndecan-1 Shedding Are Increased After Trauma.
Julie Goswami, Taleen MacArthur, Kent Bailey, Grant Spears, Rosemary A Kozar, Matthew Auton

Shock· September 2021

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Quantification of von Willebrand factor and ADAMTS-13 after traumatic injury: a pilot study.
Taleen A MacArthur, Julie Goswami, Laurie Moon Tasson, Alexander Tischer, Kent R Bailey, Matthew Auton

Trauma Surg Acute Care Open· April 2021

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Thrombin Generation Kinetics are Predictive of Rapid Transfusion in Trauma Patients Meeting Critical Administration Threshold.
Taleen A MacArthur, Grant M Spears, Rosemary A Kozar, Jing-Fei Dong, Matthew Auton

Shock· March 2021

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MeV-Stealth: A CD46-specific oncolytic measles virus resistant to neutralization by measles-immune human serum.
Miguel Ángel Muñoz-Alía, Rebecca A Nace, Alexander Tischer, Lianwen Zhang, Eugene S Bah, Matthew Auton

PLoS Pathog· February 2021

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Glycosylation sterically inhibits platelet adhesion to von Willebrand factor without altering intrinsic conformational dynamics.
Alexander Tischer, Venkata R Machha, Laurie Moon-Tasson, Linda M Benson, Matthew Auton

J Thromb Haemost· January 2020

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Evidence for the Misfolding of the A1 Domain within Multimeric von Willebrand Factor in Type 2 von Willebrand Disease.
Alexander Tischer, Maria A Brehm, Venkata R Machha, Laurie Moon-Tasson, Linda M Benson, Matthew Auton

J Mol Biol· January 2020

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Platelet-type von Willebrand disease: Local disorder of the platelet GPIbα β-switch drives high-affinity binding to von Willebrand factor.
Alexander Tischer, Venkata R Machha, Laurie Moon-Tasson, Matthew Auton

J Thromb Haemost· December 2019

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Arabinose Alters Both Local and Distal H-D Exchange Rates in the Escherichia coli AraC Transcriptional Regulator.
Alexander Tischer, Matthew J Brown, Robert F Schleif, Matthew Auton

Biochemistry· July 2019

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The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction.
Reinhard Schneppenheim, Natalie Hellermann, Maria A Brehm, Ulrike Klemm, Tobias Obser, Matthew Auton

Blood· January 2019

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"Cooperative collapse" of the denatured state revealed through Clausius-Clapeyron analysis of protein denaturation phase diagrams.
Alexander Tischer, Venkata R Machha, Jörg Rösgen, Matthew Auton

Biopolymers· August 2018

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The Chaperonin GroEL: A Versatile Tool for Applied Biotechnology Platforms.
Pierce T O'Neil, Alexandra J Machen, Benjamin C Deatherage, Caleb Trecazzi, Alexander Tischer, Matthew T Auton

Front Mol Biosci· May 2018

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Enhanced Local Disorder in a Clinically Elusive von Willebrand Factor Provokes High-Affinity Platelet Clumping.
Alexander Tischer, Venkata R Machha, Juan P Frontroth, Maria A Brehm, Tobias Obser, Matthew Auton

J Mol Biol· July 2017

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A Novel Kleefstra Syndrome-associated Variant That Affects the Conserved TPL Motif within the Ankyrin Repeat of EHMT1 Leads to Abnormal Protein Folding.
Patrick R Blackburn, Alexander Tischer, Michael T Zimmermann, Jennifer L Kemppainen, Sujatha Sastry, Matthew Auton

J Biol Chem· March 2017

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