Publications by authors named "Matthew D Eldridge"

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Decay of driver mutations shapes the landscape of intestinal transformation.
Filipe C Lourenço, Iannish D Sadien, Kim Wong, Sam Adler, Ashley Sawle, Matthew D Eldridge

Nature· December 2025

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A standardized framework for robust fragmentomic feature extraction from cell-free DNA sequencing data.
Haichao Wang, Paulius D Mennea, Yu Kiu Elkie Chan, Zhao Cheng, Maria C Neofytou, Matthew D Eldridge

Genome Biol· May 2025

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Molecular landscape and functional characterization of centrosome amplification in ovarian cancer.
Carolin M Sauer, James A Hall, Dominique-Laurent Couturier, Thomas Bradley, Anna M Piskorz, Matthew D Eldridge

Nat Commun· October 2023

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Comparison of tumor-informed and tumor-naïve sequencing assays for ctDNA detection in breast cancer.
Angela Santonja, Wendy N Cooper, Matthew D Eldridge, Paul A W Edwards, James A Morris

EMBO Mol Med· June 2023

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Rearrangement processes and structural variations show evidence of selection in oesophageal adenocarcinomas.
Alvin Wei Tian Ng, Gianmarco Contino, Sarah Killcoyne, Ginny Devonshire, Ray Hsu, Matthew D Eldridge

Commun Biol· April 2022

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NRG1 fusions in breast cancer.
Karen D Howarth, Tashfina Mirza, Susanna L Cooke, Suet-Feung Chin, Jessica C Pole, Matthew D Eldridge

Breast Cancer Res· January 2021

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Genomic copy number predicts esophageal cancer years before transformation.
Sarah Killcoyne, Eleanor Gregson, David C Wedge, Dan J Woodcock, Matthew D Eldridge

Nat Med· November 2020

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ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung.
Martijn J Schuijs, Shaun Png, Arianne C Richard, Anastasia Tsyben, Gregory Hamm, Matthew D Eldridge

Nat Immunol· September 2020

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The mutREAD method detects mutational signatures from low quantities of cancer DNA.
Juliane Perner, Sujath Abbas, Karol Nowicki-Osuch, Ginny Devonshire, Matthew D Eldridge

Nat Commun· June 2020

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Identification of Subtypes of Barrett's Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data.
SriGanesh Jammula, Annalise C Katz-Summercorn, Xiaodun Li, Constanza Linossi, Elizabeth Smyth, Matthew D Eldridge

Gastroenterology· May 2020

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GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability.
Gregoriy A Dokshin, Gregory M Davis, Ashley D Sawle, Matthew D Eldridge, Peter K Nicholls

Dev Cell· January 2020

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Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma.
Ayesha Noorani, Xiaodun Li, Martin Goddard, Jason Crawte, Ludmil B Alexandrov, Matthew D Eldridge

Nat Genet· January 2020

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Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction.
Jan Bornschein, Lorenz Wernisch, Maria Secrier, Ahmad Miremadi, Juliane Perner, Matthew D Eldridge

Int J Cancer· December 2019

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The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic.
Alexander M Frankell, SriGanesh Jammula, Xiaodun Li, Gianmarco Contino, Sarah Killcoyne, Matthew D Eldridge

Nat Genet· March 2019

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Enhanced detection of circulating tumor DNA by fragment size analysis.
Florent Mouliere, Dineika Chandrananda, Anna M Piskorz, Elizabeth K Moore, James Morris, Matthew D Eldridge

Sci Transl Med· November 2018

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Disseminated Mycobacterium malmoense and Salmonella Infections Associated with a Novel Variant in NFKBIA.
Emily Staples, Beatriz Morillo-Gutierrez, Jessica Davies, Daniel Petersheim, Michel Massaad, Matthew D Eldridge

J Clin Immunol· July 2017

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Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours.
Louise Harewood, Kamal Kishore, Matthew D Eldridge, Steven Wingett, Danita Pearson

Genome Biol· June 2017

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Corrigendum: Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance.
Maria Secrier, Xiaodun Li, Nadeera de Silva, Matthew D Eldridge, Gianmarco Contino

Nat Genet· January 2017

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Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance.
Maria Secrier, Xiaodun Li, Nadeera de Silva, Matthew D Eldridge, Gianmarco Contino

Nat Genet· October 2016

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Whole-genome sequencing of nine esophageal adenocarcinoma cell lines.
Gianmarco Contino, Matthew D Eldridge, Maria Secrier, Lawrence Bower, Rachael Fels Elliott

F1000Res· September 2016

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The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer.
Greg L Shaw, Hayley Whitaker, Marie Corcoran, Mark J Dunning, Hayley Luxton, Matthew D Eldridge

Eur Urol· August 2016

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A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.
Tyler S Alioto, Ivo Buchhalter, Sophia Derdak, Barbara Hutter, Matthew D Eldridge

Nat Commun· December 2015

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Mobile element insertions are frequent in oesophageal adenocarcinomas and can mislead paired-end sequencing analysis.
Anna L Paterson, Jamie M J Weaver, Matthew D Eldridge, Simon Tavaré, Rebecca C Fitzgerald

BMC Genomics· July 2015

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Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis.
Jamie M J Weaver, Caryn S Ross-Innes, Nicholas Shannon, Andy G Lynch, Tim Forshew, Matthew D Eldridge

Nat Genet· August 2014

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Multi-genome alignment for quality control and contamination screening of next-generation sequencing data.
James Hadfield, Matthew D Eldridge

Front Genet· March 2014

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