Publications by authors named "Matthew D Howell"

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High densities of hatchery-origin white sturgeon suppress somatic growth rates of an endangered wild population.
James A Crossman, Josh Korman, Jason G McLellan, Andy L Miller, Matthew D Howell

Ecol Appl· June 2025

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Multifunctional Tasks and an Energy Crisis are Crucial Players in Determining the Vulnerability of the Entorhinal Cortex to Early Damage in Alzheimer's Disease.
Senthilkumar Sivanesan, Matthew D Howell, Vibha Kaushik, Rajadas Jayakumar, Shree Mukilan Pari

Curr Alzheimer Res· December 2024

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Embelin and levodopa combination therapy for improved Parkinson's disease treatment.
Vagdevi Hangarakatte Ramachandra, Senthilkumar Sivanesan, Anand Koppal, Shanmugam Anandakumar, Matthew D Howell

Transl Neurosci· January 2022

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Activation of a cryptic 5' splice site reverses the impact of pathogenic splice site mutations in the spinal muscular atrophy gene.
Natalia N Singh, José Bruno Del Rio-Malewski, Diou Luo, Eric W Ottesen, Matthew D Howell

Nucleic Acids Res· December 2017

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TIA1 is a gender-specific disease modifier of a mild mouse model of spinal muscular atrophy.
Matthew D Howell, Eric W Ottesen, Natalia N Singh, Rachel L Anderson, Joonbae Seo

Sci Rep· August 2017

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Gender-Specific Amelioration of SMA Phenotype upon Disruption of a Deep Intronic Structure by an Oligonucleotide.
Matthew D Howell, Eric W Ottesen, Natalia N Singh, Rachel L Anderson, Ravindra N Singh

Mol Ther· June 2017

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Diverse role of survival motor neuron protein.
Ravindra N Singh, Matthew D Howell, Eric W Ottesen, Natalia N Singh

Biochim Biophys Acta Gene Regul Mech· March 2017

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ADAMTS expression and function in central nervous system injury and disorders.
Paul E Gottschall, Matthew D Howell

Matrix Biol· March 2016

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Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophy.
Eric W Ottesen, Matthew D Howell, Natalia N Singh, Joonbae Seo, Elizabeth M Whitley

Sci Rep· February 2016

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Hippocampal administration of chondroitinase ABC increases plaque-adjacent synaptic marker and diminishes amyloid burden in aged APPswe/PS1dE9 mice.
Matthew D Howell, Lauren A Bailey, Michael A Cozart, Brenda M Gannon, Paul E Gottschall

Acta Neuropathol Commun· September 2015

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A short antisense oligonucleotide ameliorates symptoms of severe mouse models of spinal muscular atrophy.
Jeffrey M Keil, Joonbae Seo, Matthew D Howell, Walter H Hsu, Ravindra N Singh

Mol Ther Nucleic Acids· July 2014

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Advances in therapeutic development for spinal muscular atrophy.
Matthew D Howell, Natalia N Singh, Ravindra N Singh

Future Med Chem· June 2014

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Spinal muscular atrophy: an update on therapeutic progress.
Joonbae Seo, Matthew D Howell, Natalia N Singh, Ravindra N Singh

Biochim Biophys Acta· December 2013

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Selective decline of synaptic protein levels in the frontal cortex of female mice deficient in the extracellular metalloproteinase ADAMTS1.
Matthew D Howell, Antoni X Torres-Collado, M Luisa Iruela-Arispe, Paul E Gottschall

PLoS One· April 2013

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Antisense oligonucleotide mediated therapy of spinal muscular atrophy.
Senthilkumar Sivanesan, Matthew D Howell, Christine J Didonato, Ravindra N Singh

Transl Neurosci· March 2013

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Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms.
Kevin D Phelan, U Thaung Shwe, Joel Abramowitz, Hong Wu, Sung W Rhee, Matthew D Howell

Mol Pharmacol· February 2013

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Altered synaptic marker abundance in the hippocampal stratum oriens of Ts65Dn mice is associated with exuberant expression of versican.
Matthew D Howell, Paul E Gottschall

ASN Neuro· February 2012

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Abnormal post-translational and extracellular processing of brevican in plaque-bearing mice over-expressing APPsw.
Joanne M Ajmo, Lauren A Bailey, Matthew D Howell, Lisa K Cortez, Keith R Pennypacker

J Neurochem· May 2010

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Panel of synaptic protein ELISAs for evaluating neurological phenotype.
Paul E Gottschall, Joanne M Ajmo, Autumn K Eakin, Matthew D Howell, Hina Mehta

Exp Brain Res· April 2010

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Utility of thrombocytopenia as a marker for heparin allergy in adult ED patients.
Matthew D Howell, Robert D Powers

Am J Emerg Med· May 2006

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