Publications by authors named "Ravindra N Singh"

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Pre-mRNA Splicing Modulation by Antisense Oligonucleotides.
Natalia N Singh, Diou Luo, Ravindra N Singh

Methods Mol Biol· July 2025

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Different factors underlie mild and severe forms of spinal muscular atrophy.
Eric W Ottesen, Ravindra N Singh

Brain· February 2025

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U1 snRNA interactions with deep intronic sequences regulate splicing of multiple exons of spinal muscular atrophy genes.
Eric W Ottesen, Natalia N Singh, Joonbae Seo, Ravindra N Singh

Front Neurosci· July 2024

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Transcriptome- and proteome-wide effects of a circular RNA encompassing four early exons of the spinal muscular atrophy genes.
Diou Luo, Eric W Ottesen, Ji Heon Lee, Ravindra N Singh

Sci Rep· May 2024

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A super minigene with a short promoter and truncated introns recapitulates essential features of transcription and splicing regulation of the SMN1 and SMN2 genes.
Eric W Ottesen, Joonbae Seo, Diou Luo, Natalia N Singh, Ravindra N Singh

Nucleic Acids Res· April 2024

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Synergistic Effect of an Antisense Oligonucleotide and Small Molecule on Splicing Correction of the Spinal Muscular Atrophy Gene.
Eric W Ottesen, Ravindra N Singh

Neurosci Insights· February 2024

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Diverse targets of SMN2-directed splicing-modulating small molecule therapeutics for spinal muscular atrophy.
Eric W Ottesen, Natalia N Singh, Diou Luo, Bailey Kaas, Benjamin J Gillette, Ravindra N Singh

Nucleic Acids Res· July 2023

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Structural Context of a Critical Exon of Spinal Muscular Atrophy Gene.
Natalia N Singh, Collin A O'Leary, Taylor Eich, Walter N Moss, Ravindra N Singh

Front Mol Biosci· July 2022

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Internal Introns Promote Backsplicing to Generate Circular RNAs from Spinal Muscular Atrophy Gene.
Diou Luo, Natalia Nikolaevna Singh, Ravindra Narayan Singh

Genes (Basel)· June 2022

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Commentary: Current Status of Gene Therapy for Spinal Muscular Atrophy.
Wilfried Rossoll, Ravindra N Singh

Front Cell Neurosci· May 2022

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High Concentration of an ISS-N1-Targeting Antisense Oligonucleotide Causes Massive Perturbation of the Transcriptome.
Eric William Ottesen, Diou Luo, Natalia Nikolaevna Singh, Ravindra Narayan Singh

Int J Mol Sci· August 2021

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Spinal muscular atrophy: Broad disease spectrum and sex-specific phenotypes.
Natalia N Singh, Shaine Hoffman, Prabhakara P Reddi, Ravindra N Singh

Biochim Biophys Acta Mol Basis Dis· April 2021

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Lipid residues in pottery from the Indus Civilisation in northwest India.
Akshyeta Suryanarayan, Miriam Cubas, Oliver E Craig, Carl P Heron, Vasant S Shinde, Ravindra N Singh

J Archaeol Sci· January 2021

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The First Orally Deliverable Small Molecule for the Treatment of Spinal Muscular Atrophy.
Ravindra N Singh, Eric W Ottesen, Natalia N Singh

Neurosci Insights· November 2020

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Characteristics of circular RNAs generated by human Survival Motor Neuron genes.
Eric W Ottesen, Ravindra N Singh

Cell Signal· September 2020

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A survey of transcripts generated by spinal muscular atrophy genes.
Natalia N Singh, Eric W Ottesen, Ravindra N Singh

Biochim Biophys Acta Gene Regul Mech· August 2020

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RNA in spinal muscular atrophy: therapeutic implications of targeting.
Ravindra N Singh, Joonbae Seo, Natalia N Singh

Expert Opin Ther Targets· August 2020

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How RNA structure dictates the usage of a critical exon of spinal muscular atrophy gene.
Natalia N Singh, Ravindra N Singh

Biochim Biophys Acta Gene Regul Mech· February 2020

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RNA structure and splicing regulation.
Francisco E Baralle, Ravindra N Singh, Stefan Stamm

Biochim Biophys Acta Gene Regul Mech· February 2020

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More is needed to complement the available therapies of spinal muscular atrophy.
Ravindra N Singh

Future Med Chem· November 2019

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A novel role of U1 snRNP: Splice site selection from a distance.
Ravindra N Singh, Natalia N Singh

Biochim Biophys Acta Gene Regul Mech· June 2019

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Pre-mRNA Splicing Modulation by Antisense Oligonucleotides.
Natalia N Singh, Diou Luo, Ravindra N Singh

Methods Mol Biol· April 2019

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Human Survival Motor Neuron genes generate a vast repertoire of circular RNAs.
Eric W Ottesen, Diou Luo, Joonbae Seo, Natalia N Singh, Ravindra N Singh

Nucleic Acids Res· April 2019

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Correction: Journey to the east: Diverse routes and variable flowering times for wheat and barley en route to prehistoric China.
Xinyi Liu, Diane L Lister, Zhijun Zhao, Cameron A Petrie, Xiongsheng Zeng, Ravindra N Singh

PLoS One· December 2018

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High-affinity RNA targets of the Survival Motor Neuron protein reveal diverse preferences for sequence and structural motifs.
Eric W Ottesen, Natalia N Singh, Diou Luo, Ravindra N Singh

Nucleic Acids Res· November 2018

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