Publications by authors named "Matthew During"

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Cholesterol 24-hydroxylase is a novel pharmacological target for anti-ictogenic and disease modification effects in epilepsy.
Alessia Salamone, Gaetano Terrone, Rossella Di Sapia, Silvia Balosso, Teresa Ravizza, Matthew During

Neurobiol Dis· October 2022

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OV329, a novel highly potent γ-aminobutyric acid aminotransferase inactivator, induces pronounced anticonvulsant effects in the pentylenetetrazole seizure threshold test and in amygdala-kindled rats.
Malte Feja, Sebastian Meller, Lillian S Deking, Edith Kaczmarek, Matthew J During

Epilepsia· December 2021

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Soticlestat, a novel cholesterol 24-hydroxylase inhibitor, reduces seizures and premature death in Dravet syndrome mice.
Nicole A Hawkins, Manuel Jurado, Tyler T Thaxton, Samantha E Duarte, Levi Barse, Matthew J During

Epilepsia· November 2021

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A phase 1b/2a study of soticlestat as adjunctive therapy in participants with developmental and/or epileptic encephalopathies.
Jonathan J Halford, Michael R Sperling, Dimitrios Arkilo, Mahnaz Asgharnejad, Celia Zinger, Matthew During

Epilepsy Res· August 2021

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The STARS Phase 2 Study: A Randomized Controlled Trial of Gaboxadol in Angelman Syndrome.
Lynne M Bird, Cesar Ochoa-Lubinoff, Wen-Hann Tan, Gali Heimer, Raun D Melmed, Matthew J During

Neurology· February 2021

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Platelet-Reactive Antibodies in Patients after Ischaemic Stroke-An Epiphenomenon or a Natural Protective Mechanism.
Young Eun Park, Rushi Penumarthy, Paul P Sun, Caroline Y Kang, Marie-Christine Morel-Kopp, Matthew J During

Int J Mol Sci· November 2020

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Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in mice.
Toshiya Nishi, Shinichi Kondo, Maki Miyamoto, Sayuri Watanabe, Shigeo Hasegawa, Matthew J During

Sci Rep· October 2020

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Gaboxadol Normalizes Behavioral Abnormalities in a Mouse Model of Fragile X Syndrome.
Patricia Cogram, Robert M J Deacon, Jennifer L Warner-Schmidt, Melanie J von Schimmelmann, Brett S Abrahams, Matthew J During

Front Behav Neurosci· June 2019

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Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics.
Mikail Weston, Teresa Kaserer, Angela Wu, Alexandre Mouravlev, Jenna C Carpenter, Matthew J During

Sci Adv· April 2019

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Gene therapy reduces Parkinson's disease symptoms by reorganizing functional brain connectivity.
Martin Niethammer, Chris C Tang, An Vo, Nha Nguyen, Phoebe Spetsieris, Matthew J During

Sci Transl Med· November 2018

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A clinical-grade gene therapy vector for pharmacoresistant epilepsy successfully overexpresses NPY in a human neuronal cell line.
Maria I Patrício, Alun R Barnard, Alexander L Green, Matthew J During, Arjune Sen

Seizure· February 2018

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-methyl-d-aspartate receptor mediated calcium influx supports in vitro differentiation of normal mouse megakaryocytes but proliferation of leukemic cell lines.
Tania Kamal, Taryn N Green, James I Hearn, Emma C Josefsson, Marie-Christine Morel-Kopp, Matthew J During

Res Pract Thromb Haemost· January 2018

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Inhibition of NMDA receptor function with an anti-GluN1-S2 antibody impairs human platelet function and thrombosis.
Taryn N Green, Justin R Hamilton, Marie-Christine Morel-Kopp, Zhaohua Zheng, Ting-Yu T Chen, Matthew J During

Platelets· December 2017

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Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy.
Samantha R De Silva, Alun R Barnard, Steven Hughes, Shu K E Tam, Chris Martin, Matthew J During

Proc Natl Acad Sci U S A· October 2017

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Cdc25A Is a Critical Mediator of Ischemic Neuronal Death and .
Grace O Iyirhiaro, Doo Soon Im, Wassamon Boonying, Steve M Callaghan, Matthew J During

J Neurosci· July 2017

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Long-term follow-up of a randomized AAV2- gene therapy trial for Parkinson's disease.
Martin Niethammer, Chris C Tang, Peter A LeWitt, Ali R Rezai, Maureen A Leehey, Matthew J During

JCI Insight· April 2017

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US immigration order strikes against biotech.
Jeremy M Levin, Steven H Holtzman, John Maraganore, Paul J Hastings, Ron Cohen, Matthew During

Nat Biotechnol· March 2017

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Selected GRIN2A mutations in melanoma cause oncogenic effects that can be modulated by extracellular glutamate.
Stacey Ann N D'mello, Wayne R Joseph, Taryn N Green, Euphemia Y Leung, Matthew J During

Cell Calcium· December 2016

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A Therapeutic Role for Survivin in Mitigating the Harmful Effects of Ionizing Radiation.
Katherine H Carruthers, Gregory Metzger, Eugene Choi, Matthew J During, Ergun Kocak

Sarcoma· May 2016

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Inhibition of glutamate regulated calcium entry into leukemic megakaryoblasts reduces cell proliferation and supports differentiation.
Tania Kamal, Taryn N Green, Marie-Christine Morel-Kopp, Christopher M Ward, Ailsa L McGregor, Matthew J During

Cell Signal· September 2015

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Adipose VEGF Links the White-to-Brown Fat Switch With Environmental, Genetic, and Pharmacological Stimuli in Male Mice.
Matthew J During, Xianglan Liu, Wei Huang, Daniel Magee, Andrew Slater

Endocrinology· June 2015

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Social overcrowding as a chronic stress model that increases adiposity in mice.
En-Ju D Lin, Meng Sun, Eugene Y Choi, Daniel Magee, Colin W Stets, Matthew J During

Psychoneuroendocrinology· January 2015

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Gene expression analyses identify Narp contribution in the development of L-DOPA-induced dyskinesia.
Fanny Charbonnier-Beaupel, Marion Malerbi, Cristina Alcacer, Khadija Tahiri, Wassila Carpentier, Matthew During

J Neurosci· January 2015

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Network modulation following sham surgery in Parkinson's disease.
Ji Hyun Ko, Andrew Feigin, Paul J Mattis, Chris C Tang, Yilong Ma, Matthew J During

J Clin Invest· August 2014

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Adipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype.
Xianglan Liu, Daniel Magee, Chuansong Wang, Travis McMurphy, Andrew Slater, Matthew During

Mol Ther Methods Clin Dev· February 2014

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