Publications by authors named "Matthew Holt"

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Pharmacological Therapies in Paroxysmal Nocturnal Haemoglobinuria: Focus on Complement Inhibition.
Richard J Kelly, Matthew Holt, Jeff Szer

Drugs· November 2025

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DeepMVP: deep learning models trained on high-quality data accurately predict PTM sites and variant-induced alterations.
Bo Wen, Chenwei Wang, Kai Li, Ping Han, Matthew V Holt

Nat Methods· September 2025

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COOKIE-Pro: covalent inhibitor binding kinetics profiling on the proteome scale.
Hanfeng Lin, Bin Yang, Lang Ding, Yen-Yu Yang, Matthew V Holt

Nat Commun· September 2025

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Proteogenomic characterization unveils biomarkers associated with chemoresistance in muscle-invasive bladder cancer.
Matthew V Holt, Yongchao Dou, Meggie N Young, Alexander B Saltzman, Meenakshi Anurag

Cell Rep Med· August 2025

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Genomic potential of crustose coralline algae-associated bacteria for the biosynthesis of novel antimicrobials.
Diego Lera-Lozano, Jordan S Ruiz-Toquica, Samantha A Kratman, Matthew W Holt, Clancy A McIntyre

Microb Genom· July 2025

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The 100 highest-cited original articles in large vessel occlusions: A bibliometric analysis.
Ataollah Shahbandi, Matthew Holt, Nathan A Shlobin

Neuroradiol J· June 2025

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First cases of danicopan use in adolescent patients with paroxysmal nocturnal haemoglobinuria.
Matthew Holt, Richard Kelly, Samantha Hughes, Talha Munir, Abraham Varghese

Br J Haematol· June 2025

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Effectiveness of Iptacopan Versus C5 Inhibitors in Complement Inhibitor-Naive Patients With Paroxysmal Nocturnal Haemoglobinuria.
Matthew Holt, Richard J Kelly, Jilles M Fermont, Soudeh Ansari, Marion Dahlke

EJHaem· June 2025

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Proteogenomic analysis of the CALGB 40601 (Alliance) HER2+ breast cancer neoadjuvant trial reveals resistance biomarkers.
Eric J Jaehnig, Aranzazu Fernandez-Martinez, Tanmayi D Vashist, Matthew V Holt, LaTerrica Williams

Cell Rep Med· June 2025

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COOKIE-Pro: Covalent Inhibitor Binding Kinetics Profiling on the Proteome Scale.
Hanfeng Lin, Bin Yang, Lang Ding, Yen-Yu Yang, Matthew V Holt

bioRxiv· June 2025

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Retro-Orbital Delivery of AAVs for CNS Wide Astrocyte Targeting.
Domenico Natale, Matthew Holt

Methods Mol Biol· May 2025

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G-CSF Only Versus Chemotherapy and G-CSF Peripheral Blood Stem Cell Mobilization for Autologous Hematopoietic Stem Cell Transplant-Assessing a Change in Regime due to the COVID-19 Pandemic.
Julia S Wolf, Frances Seymour, Christopher Parrish, Thea Chandler, Matthew Holt

J Clin Apher· April 2025

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Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity.
Amy Dashwood, Ntombizodwa Makuyana, Rob van der Kant, Arman Ghodsinia, Alvaro R Hernandez, Matthew G Holt

Comput Struct Biotechnol J· March 2025

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The astrocyte α1A-adrenoreceptor is a key component of the neuromodulatory system in mouse visual cortex.
Jérôme Wahis, Cansu Akkaya, Andre M Kirunda, Aline Mak, Karen Zeise, Matthew G Holt

Glia· November 2024

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Association of Serum Biomarkers With Neurocognitive Decline After PCI in Small Cell Lung Cancer: An Exploratory Study of the Phase III NCT01780675 Trial.
Haiyan Zeng, Lizza E L Hendriks, José Belderbos, Lloyd Brandts, Inge Compter, Matthew G Holt

Clin Lung Cancer· November 2024

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PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer.
Anran Chen, Beom-Jun Kim, Aparna Mitra, Craig T Vollert, Jonathan T Lei, Matthew V Holt

Mol Cancer Ther· October 2024

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Death-associated protein kinase 3 modulates migration and invasion of triple-negative breast cancer cells.
Junkai Wang, Anh M Tran-Huynh, Beom-Jun Kim, Doug W Chan, Matthew V Holt

PNAS Nexus· September 2024

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Regulatory T cells as a possible new target in epilepsy?
Evelien Hendrix, Maxime Vande Vyver, Matthew Holt, Ilse Smolders

Epilepsia· August 2024

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Do we really apply evidence-based-recommendations to spine surgery? Results of an international survey.
Ismail Bozkurt, Matthew W Holt, Eric C Robinson, Bipin Chaurasia, Mehmet Zileli

Neurosurg Rev· June 2024

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Treatment outcomes of complement protein C5 inhibition in 509 UK patients with paroxysmal nocturnal hemoglobinuria.
Richard J Kelly, Matthew Holt, Jennifer Vidler, Louise M Arnold, Joanna Large

Blood· March 2024

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Correction: Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution.
Araks Martirosyan, Rizwan Ansari, Francisco Pestana, Katja Hebestreit, Hayk Gasparyan, Matthew G Holt

Mol Neurodegener· March 2024

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Intracortical brain-computer interfaces for improved motor function: a systematic review.
Matthew W Holt, Eric C Robinson, Nathan A Shlobin, Jacob T Hanson, Ismail Bozkurt

Rev Neurosci· February 2024

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Apparent changes in RhD status during pregnancy: A case study of weak D variant due to RHD*DAU-2.
Matthew Holt, Shane Grimsley, Matthew Hazell, Tom Bullock, Tracey Watson

Transfus Med· February 2024

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Kinase inhibitor pulldown assay (KiP) for clinical proteomics.
Alexander B Saltzman, Doug W Chan, Matthew V Holt, Junkai Wang, Eric J Jaehnig

Clin Proteomics· January 2024

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Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution.
Araks Martirosyan, Rizwan Ansari, Francisco Pestana, Katja Hebestreit, Hayk Gasparyan, Matthew G Holt

Mol Neurodegener· January 2024

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