Publications by authors named "Matthew OMeara"

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Phenotypic Screening Coupled with AI-Driven Target Deconvolution Identifies α-Terthienyl as a Dual DPP-IV/HSD17β13 Modulator with Efficacy in a Mouse Model of MASLD.
Kathryn M Hoegeman, Jesse W Wotring, Reid Fursmidt, Jedidiah Gaetz, Ehab M Khalil

bioRxiv· December 2025

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cubic: CUDA-accelerated 3D Bioimage Computing.
Alexandr A Kalinin, Anne E Carpenter, Shantanu Singh, Matthew J O'Meara

ArXiv· October 2025

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Predicting the structural impact of human alternative splicing.
Yuxuan Song, Chengxin Zhang, Gilbert S Omenn, Matthew J O'Meara, Joshua D Welch

Genome Biol· September 2025

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Foreground-aware Virtual Staining for Accurate 3D Cell Morphological Profiling.
Alexandr A Kalinin, Paula Llanos, Theresa Maria Sommer, Giovanni Sestini, Xinhai Hou

ArXiv· July 2025

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Deep homology and design of proteasome chaperone proteins in .
Jackson R Rapala, Mohammad Siddiq, Patricia J Wittkopp, Matthew J O'Meara, Teresa R O'Meara

bioRxiv· May 2025

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AMP-activated protein kinase (AMPK) is essential for tendon homeostasis and prevents premature senescence and ectopic calcification.
LeeAnn A Hold, Nicole Migotsky, Syeda N Lamia, Steph S Steltzer, Sydney Grossman

bioRxiv· April 2025

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LUMIC: Latent diffUsion for Multiplexed Images of Cells.
Albert Hung, Charles J Zhang, Jonathan Z Sexton, Matthew J O'Meara, Joshua D Welch

bioRxiv· November 2024

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CryptoCEN: A Co-Expression Network for Cryptococcus neoformans reveals novel proteins involved in DNA damage repair.
Matthew J O'Meara, Jackson R Rapala, Connie B Nichols, A Christina Alexandre, R Blake Billmyre

PLoS Genet· February 2024

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Predicting the Structural Impact of Human Alternative Splicing.
Yuxuan Song, Chengxin Zhang, Gilbert S Omenn, Matthew J O'Meara, Joshua D Welch

bioRxiv· December 2023

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CryptoCEN: A Co-Expression Network for reveals novel proteins involved in DNA damage repair.
Matthew J O'Meara, Jackson R Rapala, Connie B Nichols, Christina Alexandre, R Blake Billmyre

bioRxiv· August 2023

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Imaging-Based Screening Identifies Modulators of the Translation Initiation Factor Complex in Candida albicans.
Katura Metzner, Matthew J O'Meara, Benjamin Halligan, Jesse W Wotring, Jonathan Z Sexton

Antimicrob Agents Chemother· July 2023

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Multiple ParA/MinD ATPases coordinate the positioning of disparate cargos in a bacterial cell.
Lisa T Pulianmackal, Jose Miguel I Limcaoco, Keerthikka Ravi, Sinyu Yang, Jeffrey Zhang

Nat Commun· June 2023

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A human liver organoid screening platform for DILI risk prediction.
Charles J Zhang, Sophia R Meyer, Matthew J O'Meara, Sha Huang, Meghan M Capeling

J Hepatol· May 2023

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Candida albicans selection for human commensalism results in substantial within-host diversity without decreasing fitness for invasive disease.
Faith M Anderson, Noelle D Visser, Kevin R Amses, Andrea Hodgins-Davis, Alexandra M Weber

PLoS Biol· May 2023

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Imaging-based screening identifies modulators of the translation initiation factor complex in .
Katura Metzner, Matthew J O'Meara, Benjamin Halligan, Jesse W Wotring, Jonathan Z Sexton

bioRxiv· April 2023

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The life and times of endogenous opioid peptides: Updated understanding of synthesis, spatiotemporal dynamics, and the clinical impact in alcohol use disorder.
Elyssa B Margolis, Madelyn G Moulton, Philip S Lambeth, Matthew J O'Meara

Neuropharmacology· March 2023

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Development of an automated screen for Kv7.2 potassium channels and discovery of a new agonist chemotype.
Ciria C Hernandez, Rahilla A Tarfa, Jose Miguel I Limcaoco, Ruiting Liu, Pravat Mondal

Bioorg Med Chem Lett· September 2022

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Prioritizing Virtual Screening with Interpretable Interaction Fingerprints.
Alexandre V Fassio, Laura Shub, Luca Ponzoni, Jessica McKinley, Matthew J O'Meara

J Chem Inf Model· September 2022

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In Vitro Evaluation and Mitigation of Niclosamide's Liabilities as a COVID-19 Treatment.
Jesse W Wotring, Sean M McCarty, Khadija Shafiq, Charles J Zhang, Theophilus Nguyen

Vaccines (Basel)· August 2022

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Correction to "The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design".
Rebecca F Alford, Andrew Leaver-Fay, Jeliazko R Jeliazkov, Matthew J O'Meara, Frank P DiMaio

J Chem Theory Comput· July 2022

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In Vitro Evaluation and Mitigation of Niclosamide's Liabilities as a COVID-19 Treatment.
Jesse W Wotring, Sean M McCarty, Khadija Shafiq, Charles J Zhang, Theophilus Nguyen

bioRxiv· July 2022

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Arterial Blood Gases and Arterial Lines in the Prehospital Setting: A Systematic Literature Review and Survey of Current United Kingdom Helicopter Emergency Medical Services.
Sarah Morton, Pascale Avery, Jessie Payne, Matthew OMeara

Air Med J· April 2022

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A 6-year case series of resuscitative thoracotomies performed by a helicopter emergency medical service in a mixed urban and rural area with a comparison of blunt versus penetrating trauma.
Phillip Almond, Sarah Morton, Matthew OMeara, Neal Durge

Scand J Trauma Resusc Emerg Med· January 2022

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Structures of the σ receptor enable docking for bioactive ligand discovery.
Assaf Alon, Jiankun Lyu, Joao M Braz, Tia A Tummino, Veronica Craik

Nature· December 2021

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