Publications by authors named "Matthias Christgen"

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NMD-insensitive CDH1 mutation as a mechanism for retained E-cadherin protein expression in lobular carcinoma in situ (LCIS).
Matthias Christgen, Stephan Bartels, Hans Kreipe

Histopathology· December 2025

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Multiomic factor analysis for pathologic complete response after pembrolizumab + trastuzumab + pertuzumab in HER2-enriched early breast cancer: WSG-Keyriched-1 trial.
Monika Graeser, Oleg Gluz, Peter Schmid, Katarzyna Jóźwiak, Christine Zu Eulenburg, Matthias Christgen

Clin Cancer Res· November 2025

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Multimodal Artificial Intelligence Model From Baseline Histopathology Adds Prognostic Information for Distant Recurrence Assessment in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer.
Daniel Kates-Harbeck, Hans Kreipe, Oleg Gluz, Matthias Christgen, Sherko Kuemmel

JCO Clin Cancer Inform· November 2025

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Results of the First Folate Receptor Alpha Testing Trial by the German Quality Assurance Initiative in Pathology (QuIP).
Alexander Scheiter, Sven Mattern, Verena Gassenmaier, Hans-Ulrich Schildhaus, Matthias Christgen

Cancers (Basel)· November 2025

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A predictive endocrine resistance index accurately stratifies luminal breast cancer treatment responders and nonresponders.
Guokun Zhang, Vindi Jurinovic, Stephan Bartels, Matthias Christgen, Henriette Christgen

J Clin Invest· October 2025

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The Janus Face of SPAG6: Inducing EMT in Luminal Breast Cancer Cells Amidst Widespread Expression Loss in Breast Tumours.
Antonio Sechi, Jolein Mijnes, Sophia Villwock, Michael Rose, Florian Steib, Matthias Christgen

J Cell Mol Med· October 2025

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Pitfalls in the Histological Diagnosis of Morphologic Variants of Invasive Lobular Carcinoma of the Breast.
Giuseppe Floris, Lounes Djerroudi, Gitte Zels, Maxim De Schepper, François Richard, Matthias Christgen

Mod Pathol· September 2025

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Clinicopathological Characteristics of a Distinct Tumor Phenotype: Invasive Lobular Carcinoma With Tubular Elements in the West German Study Group ADAPTcycle Trial.
Martin Radner, Sandy Burmeister, Katarzyna Jóźwiak, Nora Schaumann, Malte Gronewold, Henriette Christgen, Matthias Christgen

Lab Invest· June 2025

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In response to "Classification of Invasive Lobular Carcinoma".
Maxim De Schepper, Thijs Koorman, François Richard, Matthias Christgen, Anne Vincent-Salomon

Mod Pathol· June 2025

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Afadin loss induces breast cancer metastasis through destabilisation of E-cadherin to F-actin linkage.
Max Ak Rätze, Lotte Nfl Enserink, Noboru Ishiyama, Sven van Kempen, Christina Hj Veltman, Matthias Christgen

J Pathol· May 2025

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Chemotherapy-free neoadjuvant pembrolizumab combined with trastuzumab and pertuzumab in HER2-enriched early breast cancer (WSG-KEYRICHED-1): a single-arm, phase 2 trial.
Sherko Kuemmel, Monika Graeser, Peter Schmid, Mattea Reinisch, Friedrich Feuerhake, Matthias Christgen

Lancet Oncol· May 2025

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Immunomodulatory gene networks predict treatment response and survival to de-escalated, anthracycline-free neoadjuvant chemotherapy in triple-negative breast cancer in the WSG-ADAPT-TN trial.
Darren Korbie, Clare Stirzaker, Oleg Gluz, Christine Zu Eulenburg, Ulrike Nitz, Matthias Christgen

Mol Cancer· March 2025

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Deficient cell-cell cohesion is linked with lobular localization in simplified models of lobular carcinoma in situ (LCIS).
Matthias Christgen, Rodrigo A Caetano, Michael Eisenburger, Arne Traulsen, Philipp M Altrock

Math Biosci· February 2025

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HER2-low status as a distinct breast cancer subtype: myth or truth? Analysis of the WSG trials WSG-ADAPT-HR+/HER2-, WSG-PlanB, and WSG-ADAPT-TN.
Gilda Schmidt, Oleg Gluz, Matthias Christgen, Mattea Reinisch, Sherko Kümmel

Breast Cancer Res· February 2025

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Genetic Alterations, Therapy Response, and Survival Among Patients With Triple-Negative Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial.
Lisa Richters, Oleg Gluz, Nana Weber-Lassalle, Matthias Christgen, Heinz Haverkamp

JAMA Netw Open· February 2025

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Prediction of pathological complete response after neoadjuvant chemotherapy for HER2-negative breast cancer patients with routine immunohistochemical markers.
Lothar Häberle, Ramona Erber, Paul Gass, Alexander Hein, Melitta Niklos, Matthias Christgen

Breast Cancer Res· January 2025

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Integration of Pathological Criteria and Immunohistochemical Evaluation for Invasive Lobular Carcinoma Diagnosis: Recommendations From the European Lobular Breast Cancer Consortium.
Maxim De Schepper, Thijs Koorman, François Richard, Matthias Christgen, Anne Vincent-Salomon

Mod Pathol· July 2024

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Immunohistochemical marker profiles for the differentiation of collagenous spherulosis from adenoid cystic carcinoma of the breast.
Henriette L Warm, Leonie D Kandt, Nora Schaumann, Christopher Werlein, Malte Gronewold, Henriette Christgen, Matthias Christgen

Hum Pathol· June 2024

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Microenvironment-induced restoration of cohesive growth associated with focal activation of P-cadherin expression in lobular breast carcinoma metastatic to the colon.
Malte Gronewold, Isabel Grote, Stephan Bartels, Henriette Christgen, Leonie D Kandt, Matthias Christgen

J Pathol Clin Res· March 2024

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Malignant phyllodes tumor and invasive lobular breast carcinoma: Morpho-molecular characterization of an uncommon collision tumor and review of the literature.
Nora Schaumann, Stephan Bartels, Elna Kuehnle, Hans Kreipe, Matthias Christgen

Pathol Res Pract· February 2024

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Molecular Characterization and Subtyping of Breast Cancer Cell Lines Provide Novel Insights into Cancer Relevant Genes.
Claudia Pommerenke, Stefan Nagel, Josephine Haake, Anne Leena Koelz, Matthias Christgen

Cells· February 2024

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Frequency of genetic alterations differs in advanced breast cancer between metastatic sites.
Isabel Grote, Alexandra Poppe, Ulrich Lehmann, Matthias Christgen, Hans Kreipe

Genes Chromosomes Cancer· January 2024

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Multi-omic characterization of ILC and ILC-like cell lines as part of ILC cell line encyclopedia (ICLE) defines new models to study potential biomarkers and explore therapeutic opportunities.
Osama Shiraz Shah, Fangyuan Chen, Abdalla Wedn, Anokhi Kashiparekh, Beth Knapick, Matthias Christgen

bioRxiv· December 2023

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Evaluation of the routine use of E-cadherin immunohistochemistry in the typing of breast carcinomas: results of a randomized diagnostic study.
Gábor Cserni, Endre Kálmán, Nóra Udvarhelyi, Eszter Papp, Isabel Grote, Matthias Christgen

Histopathology· November 2023

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Absence of lobular carcinoma in situ is a poor prognostic marker in invasive lobular carcinoma.
Jason A Mouabbi, Akshara Singareeka Raghavendra, Roland L Bassett, Matthias Christgen, Lavinia Middleton

Eur J Cancer· September 2023

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