Publications by authors named "Noboru Ishiyama"

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α-catenin phosphorylation is actomyosin-sensitive and required for epithelial barrier functions through Afadin.
Jeanne M Quinn, Phuong M Le, Anthea Weng, Annette S Flozak, S Sai Folmsbee, Noboru Ishiyama

bioRxiv· August 2025

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Afadin loss induces breast cancer metastasis through destabilisation of E-cadherin to F-actin linkage.
Max Ak Rätze, Lotte Nfl Enserink, Noboru Ishiyama, Sven van Kempen, Christina Hj Veltman

J Pathol· May 2025

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α-Catenin force-sensitive binding and sequestration of LZTS2 leads to cytokinesis failure.
Yuou Wang, Alex Yemelyanov, Christopher D Go, Sun K Kim, Jeanne M Quinn, Noboru Ishiyama

J Cell Biol· March 2025

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Exploring the evolution and function of Canoe's intrinsically disordered region in linking cell-cell junctions to the cytoskeleton during embryonic morphogenesis.
Noah J Gurley, Rachel A Szymanski, Robert H Dowen, T Amber Butcher, Noboru Ishiyama

PLoS One· August 2023

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α-catenin mechanosensitivity as a route to cytokinesis failure through sequestration of LZTS2.
Yuou Wang, Alex Yemelyanov, Christopher D Go, Sun Kim, Jeanne M Quinn, Noboru Ishiyama

bioRxiv· August 2023

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Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects.
Noboru Ishiyama, Matthew O'Connor, Andrei Salomatov, Darlene Romashko, Shalabh Thakur

Cancer Res· May 2023

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Current and emerging therapies for Achondroplasia: The dawn of precision medicine.
Etienne Dardenne, Noboru Ishiyama, Tai-An Lin, Matthew C Lucas

Bioorg Med Chem· May 2023

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Exploring the evolution and function of Canoe’s intrinsically disordered region in linking cell-cell junctions to the cytoskeleton during embryonic morphogenesis.
Noah J Gurley, Rachel A Szymanski, Robert H Dowen, T Amber Butcher, Noboru Ishiyama

bioRxiv· March 2023

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Force-induced changes of α-catenin conformation stabilize vascular junctions independently of vinculin.
Cao Nguyen Duong, Randy Brückner, Martina Schmitt, Astrid F Nottebaum, Laura J Braun, Noboru Ishiyama

J Cell Sci· December 2021

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Calmodulin disrupts plasma membrane localization of farnesylated KRAS4b by sequestering its lipid moiety.
Benjamin M M Grant, Masahiro Enomoto, Sung-In Back, Ki-Young Lee, Teklab Gebregiworgis, Noboru Ishiyama

Sci Signal· March 2020

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Coordination of a Single Calcium Ion in the EF-hand Maintains the Off State of the Stromal Interaction Molecule Luminal Domain.
Masahiro Enomoto, Tadateru Nishikawa, Sung-In Back, Noboru Ishiyama, Le Zheng

J Mol Biol· January 2020

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Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions.
Noboru Ishiyama, Ritu Sarpal, Megan N Wood, Samantha K Barrick, Tadateru Nishikawa

Nat Commun· November 2018

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α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion.
Megan N Wood, Noboru Ishiyama, Indira Singaram, Connie M Chung, Annette S Flozak

J Cell Biol· November 2017

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Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.
Matthew J Smith, Elizabeth Ottoni, Noboru Ishiyama, Marilyn Goudreault, André Haman

Nat Commun· October 2017

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MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.
María-José Sandí, Christopher B Marshall, Marc Balan, Étienne Coyaud, Ming Zhou, Noboru Ishiyama

Sci Signal· October 2017

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Integration of Cadherin Adhesion and Cytoskeleton at Junctions.
René Marc Mège, Noboru Ishiyama

Cold Spring Harb Perspect Biol· May 2017

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Backbone resonance assignments of the F-actin binding domain of mouse αN-catenin.
Tadateru Nishikawa, Noboru Ishiyama, Feng Wang, Mitsuhiko Ikura

Biomol NMR Assign· April 2017

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An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function.
Weiyue Zheng, Masataka Umitsu, Ishaan Jagan, Charles W Tran, Noboru Ishiyama

Nat Cell Biol· November 2016

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Structural insights into endoplasmic reticulum stored calcium regulation by inositol 1,4,5-trisphosphate and ryanodine receptors.
Min-Duk Seo, Masahiro Enomoto, Noboru Ishiyama, Peter B Stathopulos, Mitsuhiko Ikura

Biochim Biophys Acta· September 2015

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Structural Determinants of the Mechanical Stability of α-Catenin.
Jing Li, Jillian Newhall, Noboru Ishiyama, Cara Gottardi, Mitsuhiko Ikura

J Biol Chem· July 2015

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α-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism.
David J Escobar, Ridhdhi Desai, Noboru Ishiyama, Stephen S Folmsbee, Megan N Novak

J Cell Sci· March 2015

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Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).
Mohammad T Mazhab-Jafari, Christopher B Marshall, Jason Ho, Noboru Ishiyama, Vuk Stambolic

J Biol Chem· May 2014

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An autoinhibited structure of α-catenin and its implications for vinculin recruitment to adherens junctions.
Noboru Ishiyama, Nobutoshi Tanaka, Kentaro Abe, Yoo Jeong Yang, Yazan M Abbas

J Biol Chem· May 2013

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Monomeric α-catenin links cadherin to the actin cytoskeleton.
Ridhdhi Desai, Ritu Sarpal, Noboru Ishiyama, Milena Pellikka, Mitsuhiko Ikura

Nat Cell Biol· March 2013

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Themes and variations in ER/SR calcium release channels: structure and function.
Peter B Stathopulos, Min-duk Seo, Masahiro Enomoto, Fernando J Amador, Noboru Ishiyama

Physiology (Bethesda)· December 2012

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