Publications by authors named "Matthias Quick"

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Mechanistic snapshots of lipid-linked sugar transfer.
Ryan T Morgan, Stefano Motta, Eva Gil-Iturbe, Biddut Bhattacharjee, Mohammad T Anwar, Matthias Quick

Nat Commun· December 2025

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Impact of anionic lipids on the energy landscape of conformational transition in anion exchanger 1 (AE1).
Tianle Chen, Francesca Vallese, Eva Gil-Iturbe, Kookjoo Kim, Tito Calì, Matthias Quick

Nat Commun· November 2025

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A comparative analysis reveals electrogenic properties of PfCRT and pendrin.
Eva Gil-Iturbe, Matthias Quick

J Biol Chem· October 2025

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Collateral hypersensitivity between ZY19489 and piperaquine neutralizes PfCRT-mediated drug efflux and Plasmodium falciparum resistance.
John Okombo, Tolla Ndiaye, Tarrick Qahash, Igor M R Moura, Eva Gil-Iturbe, Matthias Quick

Res Sq· October 2025

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Effects of the Quinone Analog Ubiquinone-5 on Murine Mitochondria and Hypnosis.
Yash R Somnay, Aili Wang, Haeun Lim, Keren K Griffiths, Fereshteh Zandkarimi, Matthias Quick

Anesthesiology· September 2025

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Identification of Small-Molecule Inhibitors that Block the GTP-Binding Pocket of K-Ras and Other Members of the Ras Superfamily of Small GTPases.
Luca Carta, Rebecca Hutcheson, Carolina L Bigarella, Sufang Zhang, Simon A Davis, Matthias Quick

Mol Cancer Ther· September 2025

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Sexually dimorphic mechanisms of VGLUT-mediated protection from dopaminergic neurodegeneration.
Silas A Buck, Sophie A Rubin, Tenzin Kunkhyen, Christoph D Treiber, Xiangning Xue, Matthias Quick

bioRxiv· July 2025

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quinine resistance is multifactorial and includes a role for the drug/metabolite transporters PfCRT and DMT1.
Mariko Kanai, Sachel Mok, Tomas Yeo, Melanie J Shears, Jin H Jeon, Matthias Quick

bioRxiv· April 2025

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Alternating access of a bacterial homolog of neurotransmitter: sodium symporters determined from AlphaFold2 ensembles and DEER spectroscopy.
Alexandra C Schwartz, Richard A Stein, Eva Gil-Iturbe, Matthias Quick, Hassane S Mchaourab

Proc Natl Acad Sci U S A· October 2024

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A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants.
Letícia Tiburcio Ferreira, Gustavo Capatti Cassiano, Luis Carlos Salazar Alvarez, John Okombo, Juliana Calit, Matthias Quick

PLoS Pathog· October 2024

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Structural and molecular basis of choline uptake into the brain by FLVCR2.
Rosemary J Cater, Dibyanti Mukherjee, Eva Gil-Iturbe, Satchal K Erramilli, Ting Chen, Matthias Quick

Nature· May 2024

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Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered physiology.
Laura M Hagenah, Satish K Dhingra, Jennifer L Small-Saunders, Tarrick Qahash, Andreas Willems, Matthias Quick

mBio· January 2024

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Mechanism of anion exchange and small-molecule inhibition of pendrin.
Lie Wang, Anthony Hoang, Eva Gil-Iturbe, Arthur Laganowsky, Matthias Quick

Nat Commun· January 2024

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Mapping the genomic landscape of multidrug resistance in and its impact on parasite fitness.
Sachel Mok, Tomas Yeo, Davin Hong, Melanie J Shears, Leila S Ross, Matthias Quick

Sci Adv· November 2023

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Structural and molecular basis of choline uptake into the brain by FLVCR2.
Rosemary J Cater, Dibyanti Mukherjee, Eva Gil Iturbe, Satchal K Erramilli, Ting Chen, Matthias Quick

bioRxiv· October 2023

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Insight into the mechanism of H-coupled nucleobase transport.
Jun Weng, Xiaoming Zhou, Pattama Wiriyasermkul, Zhenning Ren, Kehan Chen, Matthias Quick

Proc Natl Acad Sci U S A· August 2023

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Mapping the genomic landscape of multidrug resistance in and its impact on parasite fitness.
Sachel Mok, Tomas Yeo, Davin Hong, Melanie J Shears, Leila S Ross, Matthias Quick

bioRxiv· June 2023

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Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia.
Marta Galán-Díez, Florence Borot, Abdullah Mahmood Ali, Junfei Zhao, Eva Gil-Iturbe, Matthias Quick

Cancer Discov· April 2022

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Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance.
Jennifer L Small-Saunders, Laura M Hagenah, Kathryn J Wicht, Satish K Dhingra, Ioanna Deni, Matthias Quick

PLoS Pathog· February 2022

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Crystal structures of LeuT reveal conformational dynamics in the outward-facing states.
Jianjun Fan, Yang Xiao, Matthias Quick, Yuwei Yang, Ziyi Sun

J Biol Chem· August 2021

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Insight into the direct interaction of Na with NhaA and mechanistic implications.
Matthias Quick, Manish Dwivedi, Etana Padan

Sci Rep· March 2021

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A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition.
Dorota Focht, Caroline Neumann, Joseph Lyons, Ander Eguskiza Bilbao, Rickard Blunck, Matthias Quick

EMBO J· January 2021

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Structure of human GABA receptor in an inactive state.
Jinseo Park, Ziao Fu, Aurel Frangaj, Jonathan Liu, Lidia Mosyak, Matthias Quick

Nature· August 2020

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Author Correction: Structure of human GABA receptor in an inactive state.
Jinseo Park, Ziao Fu, Aurel Frangaj, Jonathan Liu, Lidia Mosyak, Matthias Quick

Nature· July 2020

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X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release.
Kamil Gotfryd, Thomas Boesen, Jonas S Mortensen, George Khelashvili, Matthias Quick

Nat Commun· February 2020

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