Publications by authors named "Simon A Davis"

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Identification of Small-Molecule Inhibitors that Block the GTP-Binding Pocket of K-Ras and Other Members of the Ras Superfamily of Small GTPases.
Luca Carta, Rebecca Hutcheson, Carolina L Bigarella, Sufang Zhang, Simon A Davis

Mol Cancer Ther· September 2025

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Fragment Screening to Identify Inhibitors Targeting Ribosome Binding of Shiga Toxin 2.
Michael J Rudolph, Anastasiia M Tsymbal, Arkajyoti Dutta, Simon A Davis, Benjamin Algava

ACS Infect Dis· August 2024

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Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin.
Michael J Rudolph, Arkajyoti Dutta, Anastasiia M Tsymbal, John E McLaughlin, Yang Chen, Simon A Davis

Bioorg Med Chem· February 2024

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Structure of a transmission blocking antibody in complex with Outer surface protein A from the Lyme disease spirochete, Borreliella burgdorferi.
Michael J Rudolph, Simon A Davis, H M Emranul Haque, Monir Ejemel, Lisa A Cavacini

Proteins· November 2023

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Structural Basis of Antibody-Mediated Inhibition of Ricin Toxin Attachment to Host Cells.
David J Vance, Michael J Rudolph, Simon A Davis, Nicholas J Mantis

Biochemistry· November 2023

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Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi.
Michael J Rudolph, Simon A Davis, H M Emranul Haque, David D Weis, David J Vance

mBio· April 2023

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Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.
Michael J Rudolph, Amanda Y Poon, Simona Kavaliauskiene, Anne Grethe Myrann, Claire Reynolds-Peterson, Simon A Davis

J Mol Biol· July 2021

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Blocking Borrelia burgdorferi transmission from infected ticks to nonhuman primates with a human monoclonal antibody.
Zachary A Schiller, Michael J Rudolph, Jacqueline R Toomey, Monir Ejemel, Alan LaRochelle, Simon A Davis

J Clin Invest· June 2021

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Structural basis for the interaction of Shiga toxin 2a with a C-terminal peptide of ribosomal P stalk proteins.
Michael J Rudolph, Simon A Davis, Nilgun E Tumer, Xiao-Ping Li

J Biol Chem· November 2020

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Nuclear Localization Is Not Required for Tip60 Tumor Suppressor Activity in Breast and Lung Cancer Cells.
Priyadarshini Ravichandran, Simon A Davis, Himali Vashishtha, Azad L Gucwa, Daniel S Ginsburg

DNA Cell Biol· November 2020

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Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
Michael J Rudolph, Timothy F Czajka, Simon A Davis, Chi My Thi Nguyen, Xiao-Ping Li

J Mol Biol· February 2020

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Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Michael J Rudolph, David J Vance, Simon Kelow, Siva Krishna Angalakurthi, Sophie Nguyen, Simon A Davis

Protein Eng Des Sel· July 2018

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