Publications by authors named "Matthias Samwer"

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Identification of a Highly Cooperative PROTAC Degrader Targeting GTP-Loaded KRAS(On) Alleles.
Vesna Vetma, Ilaria Puoti, Natalia K Karolak, Sohini Chakraborti, Emelyne Diers, Matthias Samwer

J Am Chem Soc· November 2025

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Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification.
Antonio Tedeschi, Fiorella Schischlik, Francesca Rocchetti, Johannes Popow, Florian Ebner, Matthias Samwer

Mol Cancer Ther· April 2025

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Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent Activities in Mouse Models of Hematological and Solid Tumors.
James C Tarr, James M Salovich, Martin Aichinger, KyuOk Jeon, Nagarathanam Veerasamy, Matthias Samwer

J Med Chem· August 2024

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Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers.
Joseph A Newman, Angeline E Gavard, Simone Lieb, Madhwesh C Ravichandran, Katja Hauer, Matthias Samwer

Life Sci Alliance· January 2021

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Chromosome clustering by Ki-67 excludes cytoplasm during nuclear assembly.
Sara Cuylen-Haering, Mina Petrovic, Alberto Hernandez-Armendariz, Maximilian W G Schneider, Matthias Samwer

Nature· November 2020

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F-Actin Interactome Reveals Vimentin as a Key Regulator of Actin Organization and Cell Mechanics in Mitosis.
Murielle P Serres, Matthias Samwer, Binh An Truong Quang, Geneviève Lavoie, Upamali Perera

Dev Cell· January 2020

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A core problem in nuclear assembly.
Matthias Samwer, Daniel W Gerlich

Nature· September 2018

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A deep learning and novelty detection framework for rapid phenotyping in high-content screening.
Christoph Sommer, Rudolf Hoefler, Matthias Samwer, Daniel W Gerlich

Mol Biol Cell· November 2017

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Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments.
Felix Spira, Sara Cuylen-Haering, Shalin Mehta, Matthias Samwer, Anne Reversat

Elife· November 2017

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DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes.
Matthias Samwer, Maximilian W G Schneider, Rudolf Hoefler, Philipp S Schmalhorst, Julian G Jude

Cell· August 2017

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A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.
Koray Kırlı, Samir Karaca, Heinz Jürgen Dehne, Matthias Samwer, Kuan Ting Pan

Elife· December 2015

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The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis.
Matthias Samwer, Heinz-Jürgen Dehne, Felix Spira, Martin Kollmar, Daniel W Gerlich

EMBO J· July 2013

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Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease.
Jens Wagner, Sergey Ryazanov, Andrei Leonov, Johannes Levin, Song Shi, Matthias Samwer

Acta Neuropathol· June 2013

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