Publications by authors named "Matthias Treu"

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Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical Assays.
Thomas Gerstberger, Helmut Berger, Frank H Büttner, Michael Gmachl, Dirk Kessler, Matthias Treu

J Med Chem· July 2024

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Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS Inhibitor.
Joachim Bröker, Alex G Waterson, Chris Smethurst, Dirk Kessler, Jark Böttcher, Matthias Treu

J Med Chem· November 2022

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Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling.
Birgit Wilding, Dirk Scharn, Dietrich Böse, Anke Baum, Valeria Santoro, Matthias Treu

Nat Cancer· July 2022

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Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor Disrupts Serine Biosynthesis.
Harald Weinstabl, Matthias Treu, Joerg Rinnenthal, Stephan K Zahn, Peter Ettmayer

J Med Chem· September 2019

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Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases.
Patrizia Sini, Ulrich Gürtler, Stephan K Zahn, Christoph Baumann, Dorothea Rudolph, Matthias Treu

Mol Cancer Ther· October 2016

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BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose Homeostasis.
Michael P Sanderson, Joshua Apgar, Pilar Garin-Chesa, Marco H Hofmann, Dirk Kessler, Matthias Treu

Mol Cancer Ther· December 2015

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Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase.
Stefanie Peter, Jennyfer Bultinck, Kevin Myant, Laura A Jaenicke, Susanne Walz, Matthias Treu

EMBO Mol Med· December 2014

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Microwave-assisted parallel synthesis of fused heterocycles in a novel parallel multimode reactor.
Matthias Treu, Thomas Karner, Roland Kousek, Helmut Berger, Moriz Mayer

J Comb Chem· December 2008

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