Publications by authors named "Matthijs Kox"

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Letter to the Editor: Vitamin D deficiency in COVID-19: Mixing up cause and consequence.
Joost Smolders, Jody van den Ouweland, Christopher Geven, Peter Pickkers, Matthijs Kox

Metabolism· February 2021

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Increased Plasma Heparanase Activity in COVID-19 Patients.
Baranca Buijsers, Cansu Yanginlar, Aline de Nooijer, Inge Grondman, Marissa L Maciej-Hulme, Inge Jonkman, Nico A F Janssen, Nils Rother, Mark de Graaf, Peter Pickkers

Front Immunol· November 2020

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Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans.
Matthijs Kox, Lucas T van Eijk, Jelle Zwaag, Joanne van den Wildenberg, Fred C G J Sweep, Johannes G van der Hoeven, Peter Pickkers

May 2014

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The immunology of sepsis: translating new insights into clinical practice.
Matthijs Kox, Michael Bauer, Lieuwe D J Bos, Hjalmar Bouma, Thierry Calandra

Nat Rev Nephrol· January 2026

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Sepsis in patients who are immunocompromised: diagnostic challenges and future therapies.
Stefanie Deinhardt-Emmer, Benjamin G Chousterman, Joerg C Schefold, Stefanie B Flohé, Tomasz Skirecki, Matthijs Kox

Lancet Respir Med· July 2025

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Measuring mitochondrial oxygenation and respiration during systemic inflammation in humans in vivo.
Mark A Wefers Bettink, Jelle Zwaag, Bernard Schockaert, Peter Pickkers, Matthijs Kox

Sci Rep· July 2025

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Systemic inflammation impairs myelopoiesis and interferon type I responses in humans.
Farid Keramati, Guus P Leijte, Niklas Bruse, Inge Grondman, Ehsan Habibi, Matthijs Kox

Nat Immunol· May 2025

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Two Case Reports of Interferon-γ Therapy in Patients with Aspergillus Tracheobronchitis Who Developed an Immunocompromised State After Severe Abdominal Sepsis.
Teun Tramper, Jeroen Schouten, Matthijs Kox, Dorien Kiers

Am J Case Rep· April 2025

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Haemoadsorption to remove inflammatory mediators in sepsis: past, present, and future.
Nicole J B Waalders, Matthijs Kox, Peter Pickkers

Intensive Care Med Exp· March 2025

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Clinical subtypes in critically ill patients with sepsis: validation and parsimonious classifier model development.
Rombout B E van Amstel, Emma Rademaker, Jason N Kennedy, Lieuwe D J Bos, Hessel Peters-Sengers, Matthijs Kox

Crit Care· February 2025

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Postoperative Innate Immune Dysregulation, Proteomic, and Monocyte Epigenomic Changes After Colorectal Surgery: A Substudy of a Randomized Controlled Trial.
Kim I Albers-Warlé, Leonie S Helder, Laszlo A Groh, Fatih Polat, Ivo F Panhuizen, Matthijs Kox

Anesth Analg· January 2025

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Respiratory Dysfunction and Abnormal Hypoxic Ventilatory Response in Mild to Moderate Parkinson's Disease.
Jules M Janssen Daalen, Isabel R Straatsma, Jeroen W H van Hees, Amber Weevers, Veerle A van de Wetering-van Dongen, Matthijs Kox

Mov Disord Clin Pract· December 2024

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Mathematical model of the inflammatory response to acute and prolonged lipopolysaccharide exposure in humans.
Freek J A Relouw, Matthijs Kox, H Rob Taal, Birgit C P Koch, Menno W J Prins

NPJ Syst Biol Appl· December 2024

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Clinical phenotyping uncovers heterogeneous associations between corticosteroid treatment and survival in critically ill COVID-19 patients.
Niklas Bruse, Anna Motos, Rombout van Amstel, Eckart de Bie, Emma J Kooistra, Matthijs Kox

Intensive Care Med· November 2024

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Preclinical and first-in-human safety studies on a novel magnetism-based haemofiltration method.
Nicole Waalders, Dirk van Lier, Jelle Gerretsen, Lucy Moran, Kerstin A Stegmann, Matthijs Kox

Sci Rep· June 2024

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Desorption in hemoadsorption therapies: a call for more data.
Aron Jansen, Nicole Waalders, Matthijs Kox, Peter Pickkers

Crit Care· June 2024

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Profiling the dysregulated immune response in sepsis: overcoming challenges to achieve the goal of precision medicine.
Sara Cajander, Matthijs Kox, Brendon P Scicluna, Markus A Weigand, Raquel Almansa Mora

Lancet Respir Med· April 2024

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Neo-epitope detection identifies extracellular matrix turnover in systemic inflammation and sepsis: an exploratory study.
YiWen Fan, Jill Moser, Matijs van Meurs, Dorien Kiers, Jannie Marie Bülow Sand, Matthijs Kox

Crit Care· April 2024

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Phenotype-specific therapeutic efficacy of ilofotase alfa in patients with sepsis-associated acute kidney injury.
Niklas Bruse, Katerina Pardali, Maarten Kraan, Matthijs Kox, Peter Pickkers

Crit Care· February 2024

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Myeloid-Derived Suppressor-like Cells as a Prognostic Marker in Critically Ill Patients: Insights from Experimental Endotoxemia and Intensive Care Patients.
Irene T Schrijver, Jacobus Herderschee, Charlotte Théroude, Antonios Kritikos, Guus Leijte, Matthijs Kox

Cells· February 2024

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Inflammatory biomarkers to predict the prognosis of acute bacterial and viral infections.
Aline H de Nooijer, Peter Pickkers, Mihai G Netea, Matthijs Kox

J Crit Care· December 2023

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Associations of dipeptidyl-peptidase 3 with short-term outcome in a mixed admission ICU-cohort.
Dirk van Lier, Remi Beunders, Matthijs Kox, Peter Pickkers

J Crit Care· December 2023

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The gut microbiota composition has no predictive value for the endotoxin-induced immune response or development of endotoxin tolerance in humans invivo.
Niklas Bruse, Aron Jansen, Jelle Gerretsen, Danielle Rijbroek, Kiedo Wienholts, Matthijs Kox

Microbes Infect· November 2023

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Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells.
David P Schrijver, Rutger J Röring, Jeroen Deckers, Anne de Dreu, Yohana C Toner, Matthijs Kox

Nat Biomed Eng· September 2023

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Molecular mechanisms and treatment responses of pulmonary fibrosis in severe COVID-19.
Emma J Kooistra, Kilian Dahm, Antonius E van Herwaarden, Jelle Gerretsen, Melanie Nuesch Germano, Matthijs Kox

Respir Res· August 2023

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Evidence-based rationale for low dose nivolumab in critically ill patients with sepsis-induced immunosuppression.
Demy A C van den Haak, Leila-Sophie Otten, Hans J P M Koenen, Ruben L Smeets, Berber Piet, Matthijs Kox

Clin Transl Sci· June 2023

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Nuclear segmentation facilitates neutrophil migration.
Connie Shen, Eva Mulder, Wiebe Buitenwerf, Jérémy Postat, Aron Jansen, Matthijs Kox

J Cell Sci· June 2023

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Modulation of Pain Sensitivity by a Hyperventilatory Breathing Exercise and Cold Exposure Training.
Jelle Zwaag, Hans Timmerman, Peter Pickkers, Matthijs Kox

J Pain Res· June 2023

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