Publications by authors named "Megan Luckey"

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Integrin CD103 expression in naive CD8 T cells promotes cytokine-driven acquisition of memory phenotype and effector function.
Can Li, Davinna L Ligons, Dominic Lanasa, Hilary R Keller, Megan A Luckey

Immunity· November 2025

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Integrin CD103 reveals a distinct developmental pathway of autoreactive thymocytes in TCR transgenic mice.
Nurcin Liman, Can Li, Megan A Luckey, Hilary R Keller, Jie Li

Nat Commun· July 2025

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Chemokine receptor CCR9 suppresses the differentiation of CD4CD8αα intraepithelial T cells in the gut.
Can Li, Hye Kyung Kim, Praveen Prakhar, Shunqun Luo, Assiatu Crossman, Megan A Luckey

Mucosal Immunol· May 2022

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The molecular basis and cellular effects of distinct CD103 expression on CD4 and CD8 T cells.
Hilary R Keller, Davinna L Ligons, Can Li, SuJin Hwang, Megan A Luckey

Cell Mol Life Sci· August 2021

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The Cytokine Receptor IL-7Rα Impairs IL-2 Receptor Signaling and Constrains the In Vitro Differentiation of Foxp3 Treg Cells.
Adam T Waickman, Hilary R Keller, Tae-Hyoun Kim, Megan A Luckey, Xuguang Tai

iScience· August 2020

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SOCS3 is a suppressor of γc cytokine signaling and constrains generation of murine Foxp3 regulatory T cells.
Megan A Luckey, Tae-Hyoun Kim, Praveen Prakhar, Hilary R Keller, Assiatu Crossman

Eur J Immunol· July 2020

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RORγt limits the amount of the cytokine receptor γc through the prosurvival factor Bcl-x in developing thymocytes.
Davinna L Ligons, SuJin Hwang, Adam T Waickman, Joo-Young Park, Megan A Luckey

Sci Signal· August 2018

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IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion.
Cecile Le Saout, Megan A Luckey, Alejandro V Villarino, Mindy Smith, Rebecca B Hasley

JCI Insight· November 2017

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Soluble γc cytokine receptor suppresses IL-15 signaling and impairs iNKT cell development in the thymus.
Joo-Young Park, Yuna Jo, Eunhee Ko, Megan A Luckey, Yoo Kyoung Park

Sci Rep· November 2016

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The transcription factor ThPOK suppresses Runx3 and imposes CD4(+) lineage fate by inducing the SOCS suppressors of cytokine signaling.
Megan A Luckey, Motoko Y Kimura, Adam T Waickman, Lionel Feigenbaum, Alfred Singer

Nat Immunol· July 2014

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Activated T cells secrete an alternatively spliced form of common γ-chain that inhibits cytokine signaling and exacerbates inflammation.
Changwan Hong, Megan A Luckey, Davinna L Ligons, Adam T Waickman, Joo-Young Park

Immunity· June 2014

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Chronic exposure to type-I IFN under lymphopenic conditions alters CD4 T cell homeostasis.
Cecile Le Saout, Rebecca B Hasley, Hiromi Imamichi, Lueng Tcheung, Zonghui Hu, Megan A Luckey

PLoS Pathog· March 2014

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Interleukin-6 expands homeostatic space for peripheral T cells.
Changwan Hong, Anna S Nam, Hilary R Keller, Davinna L Ligons, Joo-Young Park, Megan A Luckey

Cytokine· November 2013

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Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus.
Kevin W Tinsley, Changwan Hong, Megan A Luckey, Joo-Young Park, Grace Y Kim

Blood· October 2013

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Pim1 permits generation and survival of CD4+ T cells in the absence of γc cytokine receptor signaling.
Brett A Linowes, Davinna L Ligons, Anna S Nam, Changwan Hong, Hilary R Keller, Megan A Luckey

Eur J Immunol· September 2013

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Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination.
Jee-Hyun Um, Alexandra L Brown, Samarendra K Singh, Yong Chen, Marjan Gucek, Megan A Luckey

Proc Natl Acad Sci U S A· June 2013

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γc Cytokine signaling: graduate school in thymic education.
Megan A Luckey, Jung-Hyun Park

Blood· January 2013

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The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration.
Elsa Callen, Robert B Faryabi, Megan Luckey, Bingtao Hao, Jeremy A Daniel

Immunity· December 2012

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CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1.
Davinna L Ligons, Ceren Tuncer, Brett A Linowes, Izzet Mehmet Akcay, Sema Kurtulus, Megan A Luckey

J Biol Chem· October 2012

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Intrathymic IL-7: the where, when, and why of IL-7 signaling during T cell development.
Changwan Hong, Megan A Luckey, Jung-Hyun Park

Semin Immunol· June 2012

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An in vivo IL-7 requirement for peripheral Foxp3+ regulatory T cell homeostasis.
Grace Y Kim, Davinna L Ligons, Changwan Hong, Megan A Luckey, Hilary R Keller

J Immunol· June 2012

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