Publications by authors named "Mehrdad Shamloo"

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Age-related microbiome metabolites alter RNA splicing and chromatin accessibility in the brain.
Meenakshi Chakraborty, Sophia M Shi, Imani E Porter, Daniel J Richard, Georgi K Marinov, Mehrdad Shamloo

bioRxiv· November 2025

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Mapping of catecholaminergic denervation, neurodegeneration, and inflammation in 6-OHDA-treated Parkinson's disease mice.
Matteo Santoro, Rachel K Lam, Sarah E Blumenfeld, Weiqi Tan, Peter Ciari, Mehrdad Shamloo

NPJ Parkinsons Dis· February 2025

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Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer's disease.
Andrew K Evans, Heui Hye Park, Claire E Woods, Rachel K Lam, Daniel Ryskamp Rijsketic, Mehrdad Shamloo

J Neuroinflammation· December 2024

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Mapping of catecholaminergic denervation, neurodegeneration, and inflammation in 6-OHDA-treated Parkinson's disease mice.
Matteo Santoro, Rachel K Lam, Sarah E Blumenfeld, Weiqi Tan, Peter Ciari, Mehrdad Shamloo

Res Sq· October 2024

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Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer's disease.
Andrew K Evans, Heui Hye Park, Claire E Woods, Rachel K Lam, Daniel Ryskamp Rijsketic, Mehrdad Shamloo

Res Sq· October 2024

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Locus Coeruleus and Noradrenergic Pharmacology in Neurodegenerative Disease.
Rachel A Matt, Renee S Martin, Andrew K Evans, Joel R Gever, Gabriel A Vargas, Mehrdad Shamloo

Handb Exp Pharmacol· September 2024

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Schwann cell-secreted PGE promotes sensory neuron excitability during development.
Husniye Kantarci, Pablo D Elvira, Arun P Thottumkara, Emma M O'Connell, Manasi Iyer, Mehrdad Shamloo

Cell· August 2024

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Impact of high-fat diet on cognitive behavior and central and systemic inflammation with aging and sex differences in mice.
Andrew K Evans, Nay L Saw, Claire E Woods, Laura M Vidano, Sarah E Blumenfeld, Mehrdad Shamloo

Brain Behav Immun· May 2024

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Beta-2 adrenergic receptor agonism alters astrocyte phagocytic activity and has potential applications to psychiatric disease.
Ellen R Bowen, Phillip DiGiacomo, Hannah P Fraser, Kevin Guttenplan, Benjamin A H Smith, Mehrdad Shamloo

Discov Ment Health· November 2023

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The anti-inflammatory effects of photobiomodulation are mediated by cytokines: Evidence from a mouse model of inflammation.
Shirin Shamloo, Erwin Defensor, Peter Ciari, Gaku Ogawa, Laura Vidano, Mehrdad Shamloo

Front Neurosci· April 2023

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Selective Vulnerability of the Locus Coeruleus Noradrenergic System and its Role in Modulation of Neuroinflammation, Cognition, and Neurodegeneration.
Andrew K Evans, Erwin Defensor, Mehrdad Shamloo

Front Pharmacol· November 2022

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Maturation and circuit integration of transplanted human cortical organoids.
Omer Revah, Felicity Gore, Kevin W Kelley, Jimena Andersen, Noriaki Sakai, Mehrdad Shamloo

Nature· October 2022

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Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis.
Karim M Aloul, Josefine Eilsø Nielsen, Erwin B Defensor, Jennifer S Lin, John A Fortkort, Mehrdad Shamloo

Front Immunol· June 2022

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Collagen VI Regulates Motor Circuit Plasticity and Motor Performance by Cannabinoid Modulation.
Daniel D Lam, Rhîannan H Williams, Ernesto Lujan, Koji Tanabe, Georg Huber, Mehrdad Shamloo

J Neurosci· February 2022

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Age-related neuroinflammation and pathology in the locus coeruleus and hippocampus: beta-adrenergic antagonists exacerbate impairment of learning and memory in aged mice.
Andrew K Evans, Heui Hye Park, Nay Lui Saw, Kratika Singhal, Gaku Ogawa, Mehrdad Shamloo

Neurobiol Aging· October 2021

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Enantiomers of 4-aminopentanoic acid act as false GABAergic neurotransmitters and impact mouse behavior.
Adam M Wawro, Chandresh R Gajera, Steven A Baker, Robert K Leśniak, Kathleen S Montine, Mehrdad Shamloo

J Neurochem· September 2021

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Enantiomers of 2-methylglutamate and 2-methylglutamine selectively impact mouse brain metabolism and behavior.
Adam M Wawro, Chandresh R Gajera, Steven A Baker, Robert K Leśniak, Curt R Fischer, Mehrdad Shamloo

Sci Rep· April 2021

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Beta-adrenergic receptor antagonism is proinflammatory and exacerbates neuroinflammation in a mouse model of Alzheimer's Disease.
Andrew K Evans, Pooneh M Ardestani, Bitna Yi, Heui Hye Park, Rachel K Lam, Mehrdad Shamloo

Neurobiol Dis· December 2020

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Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity.
Qingkun Liu, Emily M Johnson, Rachel K Lam, Qian Wang, Hong Bo Ye, Mehrdad Shamloo

Nat Immunol· August 2019

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LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.
Gregor Bieri, Michel Brahic, Luc Bousset, Julien Couthouis, Nicholas J Kramer, Mehrdad Shamloo

Acta Neuropathol· June 2019

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PGE signaling via the neuronal EP2 receptor increases injury in a model of cerebral ischemia.
Qingkun Liu, Xibin Liang, Qian Wang, Edward N Wilson, Rachel Lam, Mehrdad Shamloo

Proc Natl Acad Sci U S A· May 2019

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Intracerebral Delivery of Brain-Derived Neurotrophic Factor Using HyStem-C Hydrogel Implants Improves Functional Recovery and Reduces Neuroinflammation in a Rat Model of Ischemic Stroke.
Kristine Ravina, Denise I Briggs, Sezen Kislal, Zuha Warraich, Tiffany Nguyen, Mehrdad Shamloo

Int J Mol Sci· November 2018

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Early adolescent Rai1 reactivation reverses transcriptional and social interaction deficits in a mouse model of Smith-Magenis syndrome.
Wei-Hsiang Huang, David C Wang, William E Allen, Matthew Klope, Hailan Hu, Mehrdad Shamloo

Proc Natl Acad Sci U S A· October 2018

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Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo.
Opher S Kornfeld, Nir Qvit, Bereketeab Haileselassie, Mehrdad Shamloo, Paolo Bernardi

Sci Rep· September 2018

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