Publications by authors named "Mei L Go"

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A potent phenylalkylamine disrupts mycobacterial membrane bioenergetics and augments bactericidal activity of bedaquiline.
Zheng Yen Phua, Ming Li, Azhar Ali, Cedric Cheng Sheng Cheong, Kai Jie Goh, Boon Cher Goh, Mei Lin Go

iScience· July 2025

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Targeting transcription factors through an IMiD independent zinc finger domain.
Bee Hui Liu, Miao Liu, Sridhar Radhakrishnan, Meng-Yuan Dai, Chaitanya Kumar Jaladanki, Mei Lin Go

EMBO Mol Med· June 2025

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Targeting transcription factors through an IMiD independent zinc finger domain.
Bee Hui Liu, Miao Liu, Sridhar Radhakrishnan, Chaitanya Kumar Jaladanki, Chong Gao, Mei Lin Go

bioRxiv· January 2024

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Redox Cycling Dioxonaphthoimidazoliums Disrupt Iron Homeostasis in Mycobacterium bovis Bacillus Calmette-Guérin.
Ming Li, Yoshiyuki Yamada, G Marcela Rodriguez, Thomas Dick, Mei Lin Go

Microbiol Spectr· December 2022

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High-Content Phenotypic Screen of a Focused TCAMS Drug Library Identifies Novel Disruptors of the Malaria Parasite Calcium Dynamics.
Wanni Chia, Maria G Gomez-Lorenzo, Isabel Castellote, Jie Xin Tong, Rajesh Chandramohanadas, Mei Lin Go

ACS Chem Biol· November 2021

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Infigratinib Is a Reversible Inhibitor and Mechanism-Based Inactivator of Cytochrome P450 3A4.
Lloyd Wei Tat Tang, Jian Wei Teng, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Mei Lin Go

Drug Metab Dispos· September 2021

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Mechanism-Based Inactivation of Cytochrome P450 3A4 and 3A5 by the Fibroblast Growth Factor Receptor Inhibitor Erdafitinib.
Lloyd Wei Tat Tang, Jian Wei Teng, Siew Kwan Koh, Lei Zhou, Mei Lin Go

Chem Res Toxicol· July 2021

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Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 Inhibition.
Ming Li, Zheng Yen Phua, Yu Xi, Zhujun Xu, Samuel A Nyantakyi, Mei Lin Go

ACS Infect Dis· July 2020

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Rifabutin Suppresses Inducible Clarithromycin Resistance in by Blocking Induction of and .
Dinah Binte Aziz, Mei Lin Go, Thomas Dick

Antibiotics (Basel)· February 2020

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Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in .
Dereje Abate Negatu, Yoshiyuki Yamada, Yu Xi, Mei Lin Go, Matthew Zimmerman

mBio· March 2019

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Anti-survivin effect of the small molecule inhibitor YM155 in RCC cells is mediated by time-dependent inhibition of the NF-κB pathway.
Mei Yi Sim, John Shyi Peng Yuen, Mei Lin Go

Sci Rep· July 2018

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The Mycobacterial Membrane: A Novel Target Space for Anti-tubercular Drugs.
Huan Chen, Samuel A Nyantakyi, Ming Li, Pooja Gopal, Dinah B Aziz, Mei L Go

Front Microbiol· July 2018

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The mechanistic effects of the dioxonaphthoimidazolium analog YM155 in renal cell carcinoma cell cycling and apoptosis.
Mei Yi Sim, Mei Lin Go, John Shyi Peng Yuen

Life Sci· June 2018

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Curcuminoids as EBV Lytic Activators for Adjuvant Treatment in EBV-Positive Carcinomas.
Octavia Ramayanti, Mitch Brinkkemper, Sandra A W M Verkuijlen, Leni Ritmaleni, Mei Lin Go

Cancers (Basel)· March 2018

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A New Generation of Arachidonic Acid Analogues as Potential Neurological Agent Targeting Cytosolic Phospholipase A.
Cheng Yang Ng, Srinivasaraghavan Kannan, Yong Jun Chen, Francis Chee Kuan Tan, Wee Yong Ong, Mei Lin Go

Sci Rep· October 2017

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Action of YM155 on clear cell renal cell carcinoma does not depend on survivin expression levels.
Mei Yi Sim, Hung Huynh, Mei Lin Go, John Shyi Peng Yuen

PLoS One· September 2017

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Mitochondrial-Targeting MET Kinase Inhibitor Kills Erlotinib-Resistant Lung Cancer Cells.
Tianming Yang, Wai Har Ng, Huan Chen, Kamon Chomchopbun, The Hung Huynh, Mei Lin Go

ACS Med Chem Lett· August 2016

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Dioxonaphthoimidazoliums AB1 and YM155 disrupt phosphorylation of p50 in the NF-κB pathway.
Si Han Sherman Ho, Azhar Ali, Tan Min Chin, Mei Lin Go

Oncotarget· March 2016

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Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepatocellular carcinoma.
Han Kiat Ho, Boon Tin Chua, Winnie Wong, Kah Suan Lim, Vivian Teo, Mei Lin Go

Mol Oncol· October 2014

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Structure-toxicity relationship and structure-activity relationship study of 2-phenylaminophenylacetic acid derived compounds.
Yi Yun Pang, Wee Kiang Yeo, Kep Yong Loh, Mei Lin Go, Han Kiat Ho

Food Chem Toxicol· September 2014

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Restraining the flexibility of the central linker in terameprocol results in constrained analogs with improved growth inhibitory activity.
Sherman Si Han Ho, Mei Lin Go

Bioorg Med Chem Lett· November 2013

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Extraction and validation of substructure profiles for enriching compound libraries.
Wee Kiang Yeo, Mei Lin Go, Shahul Nilar

J Comput Aided Mol Des· October 2012

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Exploration and optimization of structure-activity relationships in drug design using the Taguchi method.
Wee Kiang Yeo, Kheng Lin Tan, Siang Boon Koh, Matiullah Khan, Shahul Nilar, Mei Lin Go

ChemMedChem· June 2012

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Exploring the anticancer activity of functionalized isoindigos: synthesis, drug-like potential, mode of action and effect on tumor-induced xenografts.
Xi Kai Wee, Tianming Yang, Mei Lin Go

ChemMedChem· May 2012

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Aurones as modulators of ABCG2 and ABCB1: synthesis and structure-activity relationships.
Hong May Sim, Ker Yun Loh, Wee Kiang Yeo, Chong Yew Lee, Mei Lin Go

ChemMedChem· April 2011

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