Publications by authors named "Meilin Tang"

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Synthesis of Bis-urea-Bridged Cyclopeptides via Stapling of Unprotected Peptides.
Wenfang Xiong, Peiru Chen, Jinyao Liu, Yixin Liao, Meilin Tang

Org Lett· December 2025

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Discovery of Novel Selective Estrogen Receptor β (SERβ) Agonist ()-STO021 as an Antiosteoporosis Candidate with Dual Functions of Inhibiting Osteoclastogenesis and Activating Osteoblastogenesis.
Cheng Peng, Zixiang Geng, Zhe Jiang, Jin-Feng Ning, Nan Wang, Mei-Lin Tang

J Med Chem· November 2025

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Discovery of a deuterated TNF-α small molecule modulator for potential treatment of ulcerative colitis.
Tong Song, Mengxiao Zhuang, Zhi Ying Dorothy Wong, Ge Xu, Mei-Lin Tang

Eur J Med Chem· July 2025

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Distribution and frequency of genetic mutations in three insecticide targets in field populations of in Mianyang City, Sichuan Province, China.
Hongwei Xie, Meilin Tang, Hongying Sun, Zhengzheng Huang, Mengmeng Dong

Front Cell Infect Microbiol· May 2025

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ACSS2 drives senescence-associated secretory phenotype by limiting purine biosynthesis through PAICS acetylation.
Li Yang, Jianwei You, Xincheng Yang, Ruishu Jiao, Jie Xu, Meilin Tang

Nat Commun· February 2025

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From Hit to Lead: Discovery of First-In-Class Furanone Glycoside D228 Derived from for the Treatment of Inflammatory Bowel Disease.
Mei-Lin Tang, Xiao-Yu Xiong, Heyanhao Zhang, Yun-Zhi Wang, Rong-Qian Cheng

J Med Chem· October 2024

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MCF-7 cell - derived exosomes were involved in protecting source cells from the damage caused by tributyltin chloride via transport function.
Yiren Xiong, Guoqiang Guo, Hongyi Xian, Zuqing Hu, Di Ouyang, Meilin Tang

Toxicology· June 2024

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miR-584-5p / Ykt6 - mediated autophagy - lysosome - exosome pathway as a critical route affecting the toxic effects of lead on HK-2 cells.
Yiren Xiong, Zuqing Hu, Di Ouyang, Meilin Tang, Jiayi He

Ecotoxicol Environ Saf· May 2024

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Discovery of novel tubulin CBSI from the indanone scaffold for the treatment of colorectal cancer.
Zhipeng Huo, Delin Min, Shijie Zhang, Mei-Lin Tang, Xun Sun

RSC Med Chem· December 2023

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Lysosome-related exosome secretion mediated by miR-26b / Rab31 pathway was associated with the proliferation and migration of MCF-7 cells treated with BPA.
Ying Chen, Zuqing Hu, Meilin Tang, Fan Huang, Yiren Xiong

Ecotoxicol Environ Saf· March 2023

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Discovery of First-in-Class TAK1-MKK3 Protein-Protein Interaction (PPI) Inhibitor for the Treatment of Ulcerative Colitis through Modulating TNF-α Production.
Mei-Lin Tang, Haidong Li, Jin-Feng Ning, Xiaoyan Shen, Xun Sun

J Med Chem· May 2022

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Discovery of Pyridone-Substituted Triazolopyrimidine Dual A/A AR Antagonists for the Treatment of Ischemic Stroke.
Mei-Lin Tang, Zi-Hao Wen, Jing-Huan Wang, Mei-Ling Wang, Heyanhao Zhang

ACS Med Chem Lett· March 2022

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Circulating exosome level of indigenous fish may be a novel biomarker for the integrated ecotoxicity effect of water environment.
Meilin Tang, Ying Chen, Hongyi Xian, Suqin Tan, Zhenwei Lian

Ecotoxicol Environ Saf· January 2022

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A pre-screening strategy to assess resected tumor margins by imaging cytoplasmic viscosity and hypoxia.
Hui Huang, Youpei Lin, Wenrui Ma, Jiannan Liu, Jing Han, Meilin Tang

Elife· October 2021

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Indigenous Fish-Based Assessment of Genotoxic Potentials of the Helong Reservoir in Guangzhou, China.
Hongyi Xian, Meilin Tang, Ying Chen, Zhenwei Lian, Yanfeng Li

Environ Toxicol Chem· July 2021

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Discovery of Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) and Histone Deacetylase 1 (HDAC1) Dual Inhibitors Derived from the Natural Product Saprorthoquinone.
Yang Lin, Heyanhao Zhang, Tong Niu, Mei-Lin Tang, Jun Chang

Molecules· September 2020

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Novel octapeptide-DTX prodrugs targeting MMP-7 as effective agents for the treatment of colorectal cancer with lower systemic toxicity.
Zheng-Yu Liu, Mei-Lin Tang, Jin-Feng Ning, Yun-Peng Hao, Lu Zhou

Eur J Med Chem· May 2020

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A Concise Approach to -Substituted Rhodanines through a Base-Assisted One-Pot Coupling and Cyclization Process.
Yongxi Liang, Mei-Lin Tang, Zhipeng Huo, Chenchen Zhang, Xun Sun

Molecules· March 2020

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Novel Mercapto Propionamide Derivatives with Potent New Delhi Metallo-β-Lactamase-1 Inhibitory Activity and Low Toxicity.
Zhi Meng, Mei-Lin Tang, Liting Yu, Yongxi Liang, Jilai Han

ACS Infect Dis· June 2019

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Zinc-Mediated Decarboxylative Alkylation of Gem-difluoroalkenes.
Liting Yu, Mei-Lin Tang, Chang-Mei Si, Zhi Meng, Yongxi Liang

Org Lett· August 2018

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Sulfoxide-Based Enantioselective Nazarov Cyclization: Divergent Syntheses of (+)-Isopaucifloral F, (+)-Quadrangularin A, and (+)-Pallidol.
Mei-Lin Tang, Peng Peng, Zheng-Yu Liu, Jian Zhang, Jian-Ming Yu

Chemistry· October 2016

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Discovery of novel sesquistilbene indanone analogues as potent anti-inflammatory agents.
Mei-Lin Tang, Chen Zhong, Zheng-Yu Liu, Peng Peng, Xin-Hua Liu

Eur J Med Chem· May 2016

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Differential metabolism of 3FDT and docetaxel in RLMs, rats, and HLMs.
Mei-Lin Tang, Lu Zhou, Jun Chang, Zhuo-Han Hu, Yan Qin

Eur J Med Chem· May 2016

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Baicalin maintains late-stage functional cardiomyocytes in embryoid bodies derived from murine embryonic stem cells.
Meilin Tang, Mengmeng Yin, Ming Tang, Huamin Liang, Chong Yu

Cell Physiol Biochem· March 2014

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