Publications by authors named "Meiyang Xi"

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Polylysine-polyglyceryl-10-decanoate derivatives: Enhanced antioxidant properties, stability, and bioaccessibility of resveratrol nanoemulsions.
Xiang Luo, Hongze Wu, Zhe Jiang, Yanyan Zhou, Runpu Shen, Meiyang Xi

Food Chem· December 2025

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Biomacromolecule-mediated targeted protein degradation: an emerging strategy for cancer therapy.
Meiyang Xi, Fengxia Zhang, Jingjing Zhu, Hualiang Shen, Chunlei Wu, Xiaozhong Gao, Gang Xia

Eur J Med Chem· November 2025

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Identification of Potent Leucine-Rich Repeat Kinase 2 Inhibitors by Virtual Screening and Biological Evaluation.
Hualiang Shen, Guoqi Yu, Tao Cai, Kai Hu, Tianbo Shang, Xiaoxue Bai, Yicheng Xiong, Meiyang Xi

Chem Biol Drug Des· March 2025

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Antibody-drug conjugates for targeted cancer therapy: Recent advances in potential payloads.
Meiyang Xi, Jingjing Zhu, Fengxia Zhang, Hualiang Shen, Jianhui Chen, Ziyan Xiao, Gang Xia

Eur J Med Chem· October 2024

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Recent advances in targeting leucine-rich repeat kinase 2 as a potential strategy for the treatment of Parkinson's disease.
Ruiwei Cao, Caiping Chen, Jing Wen, Weihe Zhao, Chaojun Zhang, Meiyang Xi

Bioorg Chem· December 2023

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Hyaluronic Acid Poly(glyceryl)-Stearate Derivatives: Novel Emulsifiers for Improving the Gastrointestinal Stability and Bioaccessibility of Coenzyme Q10 Nanoemulsions.
Xiang Luo, Sha Ao, Hongze Wu, David Julian McClements, Likun Fang, Meiyang Xi

J Agric Food Chem· July 2023

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Therapeutic potential of targeting kynurenine pathway in neurodegenerative diseases.
Hualiang Shen, Xinde Xu, Yalong Bai, Xiaoping Wang, Yibin Wu, Meiyang Xi

Eur J Med Chem· May 2023

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Targeting phosphodiesterase 4 as a therapeutic strategy for cognitive improvement.
Xuemei Wei, Guoqi Yu, Hualiang Shen, Yanjuan Luo, Tianbo Shang, Meiyang Xi

Bioorg Chem· January 2023

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Design, synthesis, biological evaluation and molecular modeling of N-isobutyl-N-((2-(p-tolyloxymethyl)thiazol-4yl)methyl)benzo[d][1,3] dioxole-5-carboxamides as selective butyrylcholinesterase inhibitors.
Meiyang Xi, Chengjie Feng, Kui Du, Weiping Lv, Chenxi Du

Bioorg Med Chem Lett· April 2022

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Therapeutic potential of phosphodiesterase inhibitors for cognitive amelioration in Alzheimer's disease.
Meiyang Xi, Tianyu Sun, Shejie Chai, Mengjiao Xie, Siqi Chen

Eur J Med Chem· March 2022

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Therapeutic potential of targeting SHP2 in human developmental disorders and cancers.
Dadong Shen, Wenxia Chen, Jinlin Zhu, Guofeng Wu, Runpu Shen, Meiyang Xi

Eur J Med Chem· March 2020

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Small molecule PROTACs in targeted therapy: An emerging strategy to induce protein degradation.
Meiyang Xi, Yi Chen, Hongyu Yang, Huiting Xu, Kui Du, Xiang Luo, Xiaozhong Gao

Eur J Med Chem· July 2019

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CDK8 as a therapeutic target for cancers and recent developments in discovery of CDK8 inhibitors.
Meiyang Xi, Tingkai Chen, Chunlei Wu, Xiaozhong Gao, Yonghua Wu, Xiang Luo

Eur J Med Chem· February 2019

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N'-[(3-[benzyloxy]benzylidene]-3,4,5-trihydroxybenzohydrazide (1) protects mice against colitis induced by dextran sulfate sodium through inhibiting NFκB/IL-6/STAT3 pathway.
Meiyang Xi, Xiaojian Wang, Jun Ge, Dali Yin

Biochem Biophys Res Commun· August 2016

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Development of hydroxy-based sphingosine kinase inhibitors and anti-inflammation in dextran sodium sulfate induced colitis in mice.
Meiyang Xi, Jun Ge, Xiaojian Wang, Chenbin Sun, Tianqi Liu, Qiong Xiao

Bioorg Med Chem· July 2016

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Synthesis, identification, and biological activity of metabolites of two novel selective S1P1 agonists.
Qiong Xiao, Jing Jin, Xiaojian Wang, Jinping Hu, Meiyang Xi

Bioorg Med Chem· May 2016

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Assessing the ligand selectivity of sphingosine kinases using molecular dynamics and MM-PBSA binding free energy calculations.
Liang Fang, Xiaojian Wang, Meiyang Xi, Tianqi Liu, Dali Yin

Mol Biosyst· April 2016

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Discovery and Modification of in Vivo Active Nrf2 Activators with 1,2,4-Oxadiazole Core: Hits Identification and Structure-Activity Relationship Study.
Li-Li Xu, Jun-Feng Zhu, Xiao-Li Xu, Jie Zhu, Li Li, Mei-Yang Xi, Xiao-Jin Zhang

J Med Chem· July 2015

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Insight into the intermolecular recognition mechanism between Keap1 and IKKβ combining homology modelling, protein-protein docking, molecular dynamics simulations and virtual alanine mutation.
Zheng-Yu Jiang, Hong-Xi Chu, Mei-Yang Xi, Ting-Ting Yang, Jian-Min Jia, Xiao-Ke Guo, Xiao-Jin Zhang

PLoS One· May 2014

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Discovery of potent Keap1-Nrf2 protein-protein interaction inhibitor based on molecular binding determinants analysis.
Zheng-Yu Jiang, Meng-Chen Lu, Li Li Xu, Ting-Ting Yang, Mei-Yang Xi, Xiao-Li Xu, Xiao-Ke Guo, Xiao-Jin Zhang

J Med Chem· March 2014

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Effective screening strategy using ensembled pharmacophore models combined with cascade docking: application to p53-MDM2 interaction inhibitors.
Xin Xue, Jin-Lian Wei, Li-Li Xu, Mei-Yang Xi, Xiao-Li Xu, Xiao-Ke Guo, Xiao-Jin Zhang

J Chem Inf Model· October 2013

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3-aroylmethylene-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-ones as potent Nrf2/ARE inducers in human cancer cells and AOM-DSS treated mice.
Mei-Yang Xi, Jian-Min Jia, Hao-Peng Sun, Zhong-Ying Sun, Jie-Wei Jiang, Xin Xue, Xi Yang, Xiao-Ke Guo, Xiao-Li Xu, Xiao-Jin Zhang

J Med Chem· October 2013

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Synthesis and bioevaluation of a series of α-pyrone derivatives as potent activators of Nrf2/ARE pathway (part I).
Mei-yang Xi, Zhong-ying Sun, Hao-peng Sun, Jian-min Jia, Zheng-yu Jiang, Xi Yang, Xin Xue, Xiao-ke Guo

Eur J Med Chem· August 2013

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Synthesis, SAR and biological evaluation of natural and non-natural hydroxylated and prenylated xanthones as antitumor agents.
Xiaojin Zhang, Xiang Li, Suofu Ye, Yu Zhang, Lei Tao, Meiyang Xi, Xiaoli Xu

Med Chem· November 2012

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Studies on chemical modification and biology of a natural product, gambogic acid (III): determination of the essential pharmacophore for biological activity.
Xiaojian Wang, Na Lu, Qian Yang, Dandan Gong, Changjun Lin, Meiyang Xi

Eur J Med Chem· April 2011

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