Publications by authors named "Meizhu Wu"

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Tetramethylpyrazine ameliorates 5-fluorouracil-Induced cardiotoxicity by inhibiting PANoptosis and suppressing the p38 MAPK/JNK/ERK signaling pathway.
Yi Xie, Aling Shen, Huiyun Lin, Huifang Zheng, Guosheng Lin, Meizhu Wu

Eur J Pharmacol· November 2025

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Integrative network pharmacology and experimental study of Qingda granule in hypertension-induced endothelial dysfunction.
Yanyan Yang, Qiurong Xie, Jingyi Zeng, Meizhu Wu, Daxin Chen

Exp Anim· October 2025

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[Mechanism of Trifolin in Attenuating Hypertension-Induced Renal Cell Apoptosis via Modulation of the MAPK Signaling Pathway].
Meizhu Wu, Zhi Guo, Yi Xie, Hongshu Liu, Hong Chen

Sichuan Da Xue Xue Bao Yi Xue Ban· September 2025

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Isoliensinine promotes vasorelaxation and inhibits constriction by regulating the calcium channel in hypertension: In vitro and in vivo approaches.
Meizhu Wu, Yuting Zhou, Zhi Guo, Dawei Lian, Hong Chen

Eur J Pharmacol· August 2025

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Vascular Protection of Neferine on Attenuating Angiotensin II-Induced Blood Pressure Elevation by Integrated Network Pharmacology Analysis and RNA-Sequencing Approach.
A-Ling Shen, Xiu-Li Zhang, Zhi Guo, Mei-Zhu Wu, Ying Cheng

Chin J Integr Med· August 2025

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DAPK1 acts as a positive regulator of hypertension via induction of vasoconstriction.
Xiuli Zhang, Ying Cheng, Yao Lu, Nanhui Xu, Zhi Guo, Meizhu Wu

Clin Sci (Lond)· June 2025

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Neferine attenuates hypertensive cardiomyocyte apoptosis and modulates key signaling pathways: An in vivo and in vitro study.
Zhi Guo, Meizhu Wu, Lingqi Chen, Hong Chen, Jinkong Wu

Eur J Pharmacol· May 2025

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Downregulating FGGY carbohydrate kinase domain containing promotes cell senescence by activating the p53/p21 signaling pathway in colorectal cancer.
Liya Liu, Meizhu Wu, Youqin Chen, Ying Cheng, Sijia Liu

Int J Mol Med· May 2025

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Effects and mechanisms of trifolin on attenuating hypertension-induced vascular smooth muscle cell proliferation and collagen deposition in vivo and in vitro.
Aling Shen, Meizhu Wu, Zhi Guo, Farman Ali, Jinkong Wu

Sci Rep· May 2025

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Trifolin inhibits the calcium-driven contraction pathway in vascular smooth muscle.
Renfeng Li, Jinkong Wu, Meizhu Wu, Farman Ali, Yanyan Yang

Front Pharmacol· May 2025

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Dehydrocorydaline attenuates myocardial ischemia-reperfusion injury via the FoXO signalling pathway: A multimodal study based on network pharmacology, molecular docking, and experimental study.
Hongzheng Li, Wenwen Yang, Zucheng Shang, Yingdong Lu, Aling Shen, Meizhu Wu

J Ethnopharmacol· January 2025

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[Chemical constituents of butyl-phthalides from Ligusticum sinense].
Hang Liu, Xue-Ming Zhou, Ting Zheng, Mei-Zhu Wu, Shuo Feng

Zhongguo Zhong Yao Za Zhi· January 2025

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[Wogonoside Attenuates Hypertension-Induced Renal Injury Through Modulation of the MAPK Signaling Pathway: A Mechanism Study].
Zhi Guo, Yi Xie, Hongshu Liu, Jundan Xiao, Rongji Chen, Meizhu Wu

Sichuan Da Xue Xue Bao Yi Xue Ban· January 2025

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Qing Hua Chang Yin ameliorates chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and the NF-κB signalling pathway.
Liya Liu, Youqin Chen, Yuying Han, Xinran Zhang, Yulun Wu, Meizhu Wu

Pharm Biol· December 2024

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Trifolin attenuates hypertension-mediated cardiac injury by inhibiting cardiomyocyte apoptosis: Mechanistic insights and therapeutic potential.
Fu Zhang, Zhi Guo, Meizhu Wu, Guosheng Lin, Hong Chen

Eur J Pharmacol· December 2024

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Quercetin Protects Against Hypertensive Renal Injury by Attenuating Apoptosis: An Integrated Approach Using Network Pharmacology and RNA Sequencing.
Xiu-Li Zhang, Jia-Peng Li, Mei-Zhu Wu, Jin-Kong Wu, Shu-Yu He

J Cardiovasc Pharmacol· September 2024

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Gastrodin Alleviates Angiotensin II-Induced Hypertension and Myocardial Apoptosis via Inhibition of the PRDX2/p53 Pathway In Vivo and In Vitro.
Nanhui Xu, Qiurong Xie, Youqin Chen, Jiapeng Li, Xiuli Zhang, Meizhu Wu

Pharmaceuticals (Basel)· September 2024

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[Two new pinophol derivatives from endophytic fungus Penicillium herquei JX4 hosted in Ceriops tagal].
Xian-Lei Lao, Mei-Zhu Wu, Ting Zheng, Guang-Ying Chen, Cai-Juan Zheng

Zhongguo Zhong Yao Za Zhi· July 2024

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Pien Tze Huang Inhibits Proliferation of Colorectal Cancer Cells through Suppressing PNO1 Expression and Activating p53/p21 Signaling Pathway.
Liu-Jing Cao, Li-Ya Liu, You-Qin Chen, Yu-Ying Han, Li-Hui Wei, Mei-Zhu Wu

Chin J Integr Med· June 2024

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Enhancing the therapeutic potential of isoliensinine for hypertension through PEG-PLGA nanoparticle delivery: A comprehensive in vivo and in vitro study.
Mengying Yao, Ming Wu, Meng Yuan, Meizhu Wu, Aling Shen

Biomed Pharmacother· May 2024

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Baicalin alleviates angiotensin II-induced cardiomyocyte apoptosis and autophagy and modulates the AMPK/mTOR pathway.
Ying Cheng, Mengchao Yan, Shuyu He, Yi Xie, Lihui Wei, Meizhu Wu

J Cell Mol Med· May 2024

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[Two new benzyl-benzoate glucosides from Plumeria rubra].
Zheng Chen, Mei-Zhu Wu, Ting Zheng, Ya-Lin Chen, Chen Sun

Zhongguo Zhong Yao Za Zhi· March 2024

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Plumeriapropionics A-E, Carboxyl-Substituted Phenylpropionic Acid Derivatives with Anti-Inflammatory Activity from L.
Xueming Zhou, Minlin Gan, Meizhu Wu, Ting Zheng, Chuluunbaatar Enkhchimeg

Molecules· December 2023

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Isoliensinine Attenuates Renal Fibrosis and Inhibits TGF-β1/Smad2/3 Signaling Pathway in Spontaneously Hypertensive Rats.
Mengying Yao, Dawei Lian, Meizhu Wu, Yuting Zhou, Yi Fang

Drug Des Devel Ther· September 2023

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Based on network pharmacology, gastrodin attenuates hypertension-induced vascular smooth muscle cell proliferation and PI3K/AKT pathway activation.
Aling Shen, Meizhu Wu, Farman Ali, Zhi Guo, Yi Fang

Sci Rep· July 2023

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