Publications by authors named "Meng-Kwoon Sim"

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Bioavailability of Orally Administered Des-Aspartate-Angiotensin I in Human Subjects.
Kok-Onn Lee, Edmund Feng Tian, Martin Hui Cai, Hong Wang, Yiong-Huak Chan, Meng-Kwoon Sim

Drugs R D· March 2018

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Potential Protective Effects of Ursolic Acid against Gamma Irradiation-Induced Damage Are Mediated through the Modulation of Diverse Inflammatory Mediators.
Hong Wang, Meng-Kwoon Sim, Weng Keong Loke, Arunachalam Chinnathambi, Sulaiman Ali Alharbi

Front Pharmacol· June 2017

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Author's Reply to Srinivas: "A Single Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Orally Administered Des-Aspartate Angiotensin I in Healthy Subjects".
Meng-Kwoon Sim, Kok-Onn Lee

Drugs R D· March 2017

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A Single Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Orally Administered Des-Aspartate Angiotensin I in Healthy Subjects.
Ko-Onn Lee, Chin-Meng Khoo, Balram Chowbay, Yiong-Huak Chan, Meng-Kwoon Sim

Drugs R D· December 2016

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Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action.
Hong Wang, Gautam Sethi, Weng-Keong Loke, Meng-Kwoon Sim

PLoS One· May 2016

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Des-aspartate-angiotensin I causes specific release of PGE2 and PGI2 in HUVEC via the angiotensin AT1 receptor and biased agonism.
Qiang Wen, Kok-Onn Lee, Sai-Zhen Sim, Xiao-Guang Xu, Meng-Kwoon Sim

Eur J Pharmacol· December 2015

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Des-aspartate-angiotensin I, a novel angiotensin AT(1) receptor drug.
Meng-Kwoon Sim

Eur J Pharmacol· August 2015

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Des-aspartate-angiotensin I attenuates ICAM-1 formation in hydrogen peroxide-treated L6 skeletal muscle cells and soleus muscle of mice subjected to eccentric exercise.
Meng-Kwoon Sim, Yong-Chiat Wong, Xiao-Guang Xu, Weng-Keong Loke

Regul Pept· January 2014

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Des-aspartate-angiotensin I exerts antiviral effects and attenuates ICAM-1 formation in rhinovirus-infected epithelial cells.
Lay-Teng Ang, Ling-Yin Tan, Vincent T Chow, Meng-Kwoon Sim

Eur J Pharmacol· May 2012

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Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice.
Yong-Chiat Wong, Meng-Kwoon Sim, Kok-Onn Lee

Biochem Pharmacol· November 2011

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Protective actions of des-aspartate-angiotensin I in mice model of CEES-induced lung intoxication.
Eugene Teck-Leong Ng, Meng-Kwoon Sim, Weng-Keong Loke

J Appl Toxicol· August 2011

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Effects of des-aspartate-angiotensin I on myocardial ischemia-reperfusion injury in rats.
Qiang Wen, Meng-Kwoon Sim

Eur J Pharmacol· May 2011

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Attenuated Bordetella pertussis protects against highly pathogenic influenza A viruses by dampening the cytokine storm.
Rui Li, Annabelle Lim, Meng Chee Phoon, Teluguakula Narasaraju, Jowin K W Ng, Meng Kwoon Sim

J Virol· July 2010

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Hypoglycemic action of chicken meat extract in type-2 diabetic KKAy mice and GK rats.
Meng-Kwoon Sim, Yong-Chiat Wong, Xiao-Guang Xu, Sai-Zhen Sim, Daniel Tsi

Biosci Biotechnol Biochem· December 2009

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Des-aspartate-angiotensin I exerts hypoglycemic action via glucose transporter-4 translocation in type 2 diabetic KKAy mice and GK rats.
Meng-Kwoon Sim, Xiao-Guang Xu, Yong-Chiat Wong, Sai-Zhen Sim, Kok-Onn Lee

Endocrinology· December 2007

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Effects of angiotensin 1-7 on the actions of angiotensin II in the renal and mesenteric vasculature of hypertensive and streptozotocin-induced diabetic rats.
Murugan Dharmani, Mohd Rais Mustafa, Francis I Achike, Meng-Kwoon Sim

Eur J Pharmacol· April 2007

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Effects of losartan on angiotensin receptors in the hypertrophic rat heart.
Meng-Kwoon Sim, Woei-Shin Chen

Regul Pept· December 2006

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Novel neuroprotective effects with O-benzyl derivative of pralidoxime in soman-intoxicated rodents.
Weng-Keong Loke, Meng-Kwoon Sim, Mei-Lin Go

Eur J Pharmacol· October 2005

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Des-aspartate-angiotensin I and angiotensin AT1 receptors in rat cardiac ventricles.
Meng-Kwoon Sim, Le Min

Regul Pept· July 2005

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Reduction of infarct size by orally administered des-aspartate-angiotensin I in the ischemic reperfused rat heart.
Qiang Wen, Meng-Kwoon Sim, Feng-Ru Tang

Regul Pept· August 2004

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Transport of angiotensin peptides across the Caco-2 monolayer.
Hui-Lee Chua, Seetharama Jois, Meng-Kwoon Sim, Mei-Lin Go

Peptides· August 2004

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Structure-activity and structure-binding studies of des-Asp(1)-angiotensin I analogues on the rabbit pulmonary artery.
Woei-Shin Chen, Meng-Kwoon Sim, Mei-Lin Go

Regul Pept· June 2002

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O-Substituted derivatives of pralidoxime: muscarinic properties and protection against soman effects in rats.
Weng-Keong Loke, Meng-Kwoon Sim, Mei-Lin Go

Eur J Pharmacol· May 2002

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Quinuclidinone O-Alkynyloximes with muscarinic agonist activity.
Brinda Somanadhan, Weng-Keong Loke, Meng-Kwoon Sim, Mei-Lin Go

Bioorg Med Chem· January 2002

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