Publications by authors named "Sai-Zhen Sim"

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Screening for intrinsic capacity and frailty in older adults with multimorbidity in the primary care setting: application of the ICOPE tool and two frailty instruments.
Sai Zhen Sim, Xinyao Ng, Poay Sian Sabrina Lee, Hui Li Koh, Shu Yun Tan

BMC Geriatr· November 2025

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Empowering self-assessment of frailty: A revised CFS-Self tool for primary and community care.
Sai Zhen Sim, Xinyao Ng, Wei Chun Gan, Dexin Zheng, Shu Yun Tan

Ann Geriatr Med Res· August 2025

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Targeting osteosarcopenia and multimorbidity for frailty prevention through identification and deep phenotyping methods in healthy ageing and high-burden disease cohorts (OPTIMA-C): a longitudinal observational cohort study protocol for neuromusculoskeletal muscle health.
Matthew Rong Jie Tay, Jong Moon Kim, Poo Lee Ong, Lay Wai Khin, Chin Jung Wong, Sai Zhen Sim

BMJ Open· May 2025

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The role of family health climate in physical activity and sedentary behaviour in primary care patients with diabetes - a cross-sectional study.
Amelia Ahmad Hatib, Hui Li Koh, Sai Zhen Sim

BMC Prim Care· April 2025

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Self-perceived nutrition competence of primary care physicians in Singapore: a cross-sectional study.
Andrew Yu Jing Chua, Eng Sing Lee, Poay Sian Sabrina Lee, Jeremy Kaiwei Lew, Sai Zhen Sim

Prim Health Care Res Dev· February 2025

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Understanding treatment burden in adults with multimorbidity in the Singapore primary care setting: An exploratory study using the Multimorbidity Treatment Burden Questionnaire.
Sai Zhen Sim, Si Yan Ding, Jeremy Kaiwei Lew, Eng Sing Lee

Ann Acad Med Singap· May 2024

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Cross-sectional study assessing health outcome priorities of older adults with multimorbidity at a primary care setting in Singapore.
Xin Rong Ng, Yu Xuan Sheryl Tey, Kaiwei Jeremy Lew, Poay Sian Sabrina Lee, Eng Sing Lee, Sai Zhen Sim

BMJ Open· December 2023

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Evaluation of the clinical effectiveness of telephone consultation compared to face-to-face consultation in terms of glycaemic control among patients with suboptimally controlled type 2 diabetes: a retrospective cohort study.
Zhong Wei Jeremy Koh, Sai Zhen Sim, Kaiwei Jeremy Lew, Poay Sian Sabrina Lee, Eng Sing Lee

BMJ Open· May 2023

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COVID-19 in Singapore - a case series from primary care.
Sai Zhen Sim, Sok Huang Teo, Jing Wen Kong, Ziliang Lim, Ming Yann Karen Ng

Singapore Med J· January 2021

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How does multimorbidity affect middle-aged adults? A cross-sectional survey in the Singapore primary healthcare setting.
Sai Zhen Sim, Hui Li Koh, Sabrina Poay Sian Lee, Doris Yee Ling Young, Eng Sing Lee

BMC Fam Pract· September 2020

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Des-aspartate-angiotensin I causes specific release of PGE2 and PGI2 in HUVEC via the angiotensin AT1 receptor and biased agonism.
Qiang Wen, Kok-Onn Lee, Sai-Zhen Sim, Xiao-Guang Xu, Meng-Kwoon Sim

Eur J Pharmacol· December 2015

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Hypoglycemic action of chicken meat extract in type-2 diabetic KKAy mice and GK rats.
Meng-Kwoon Sim, Yong-Chiat Wong, Xiao-Guang Xu, Sai-Zhen Sim, Daniel Tsi

Biosci Biotechnol Biochem· December 2009

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Des-aspartate-angiotensin I exerts hypoglycemic action via glucose transporter-4 translocation in type 2 diabetic KKAy mice and GK rats.
Meng-Kwoon Sim, Xiao-Guang Xu, Yong-Chiat Wong, Sai-Zhen Sim, Kok-Onn Lee

Endocrinology· December 2007

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