Publications by authors named "Metello Innocenti"

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Multiplexed imaging to reveal tissue dendritic cell spatial localisation and function.
Giuseppe Rocca, Marco Galli, Anna Celant, Giulia Stucchi, Laura Marongiu, Metello Innocenti

FEBS Lett· July 2025

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Dual-Targeting Strategy to Repurpose Cetuximab with HFn Nanoconjugates for Immunotherapy of Triple-Negative Breast Cancer.
Linda Barbieri, Lucia Salvioni, Andrea Banfi, Stefania Garbujo, Luisa Fiandra, Metello Innocenti

ACS Appl Mater Interfaces· June 2025

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Mitochondrial and energy metabolism dysfunctions are hallmarks of TDP-43 fibroblasts from members of an Amyotrophic Lateral Sclerosis family.
Elisa Perciballi, Federica Bovio, Sara Ferro, Matilde Forcella, Jessica Rosati, Metello Innocenti

Cell Death Dis· April 2025

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TGF-β Signaling Loop in Pancreatic Ductal Adenocarcinoma Activates Fibroblasts and Increases Tumor Cell Aggressiveness.
Noemi di Miceli, Chiara Baioni, Linda Barbieri, Davide Danielli, Emiliano Sala, Metello Innocenti

Cancers (Basel)· November 2024

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Aberrant cortex contractions impact mammalian oocyte quality.
Elvira Nikalayevich, Gaëlle Letort, Ghislain de Labbey, Elena Todisco, Anastasia Shihabi, Metello Innocenti

Dev Cell· April 2024

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Investigating Mammalian Formins with SMIFH2 Fifteen Years in: Novel Targets and Unexpected Biology.
Metello Innocenti

Int J Mol Sci· May 2023

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Advanced Cell Culture Models Illuminate the Interplay between Mammary Tumor Cells and Activated Fibroblasts.
Martina Del Nero, Alessandro Colombo, Stefania Garbujo, Chiara Baioni, Linda Barbieri, Metello Innocenti

Cancers (Basel)· April 2023

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A Protumorigenic mDia2-MIRO1 Axis Controls Mitochondrial Positioning and Function in Cancer-Associated Fibroblasts.
Michael Cangkrama, Huan Liu, James Whipman, Maria Zubair, Mai Matsushita, Metello Innocenti

Cancer Res· October 2022

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mDia1 Assembles a Linear F-Actin Coat at Membrane Invaginations To Drive Listeria monocytogenes Cell-to-Cell Spreading.
Aaron S Dhanda, A Wayne Vogl, Fern Ness, Metello Innocenti, Julian A Guttman

mBio· December 2021

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mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote Kras-Induced Acinar-to-Ductal Metaplasia and Early Pancreatic Carcinogenesis.
Yamin Zhao, Benjamin Schoeps, Dianbo Yao, Zhiheng Zhang, Kathleen Schuck, Metello Innocenti

Gastroenterology· April 2021

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The chloride intracellular channel protein CLIC4 inhibits filopodium formation induced by constitutively active mutants of formin mDia2.
Elisabetta Argenzio, Metello Innocenti

FEBS Lett· June 2020

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A paracrine activin A-mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming.
Michael Cangkrama, Mateusz Wietecha, Nicolas Mathis, Rin Okumura, Luca Ferrarese, Metello Innocenti

EMBO Mol Med· April 2020

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New insights into the formation and the function of lamellipodia and ruffles in mesenchymal cell migration.
Metello Innocenti

Cell Adh Migr· July 2019

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Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA-mDia2 signaling and filopodium formation.
Elisabetta Argenzio, Jeffrey Klarenbeek, Katarzyna M Kedziora, Leila Nahidiazar, Tadamoto Isogai, Metello Innocenti

J Biol Chem· December 2018

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Knockout of the Arp2/3 complex in epidermis causes a psoriasis-like disease hallmarked by hyperactivation of transcription factor Nrf2.
Rob van der Kammen, Ji-Ying Song, Iris de Rink, Hans Janssen, Stefania Madonna, Metello Innocenti

Development· December 2017

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Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors.
Daniela Leyton-Puig, Tadamoto Isogai, Elisabetta Argenzio, Bram van den Broek, Jeffrey Klarenbeek, Metello Innocenti

Nat Commun· July 2017

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Quantitative Proteomics Illuminates a Functional Interaction between mDia2 and the Proteasome.
Tadamoto Isogai, Rob van der Kammen, Onno B Bleijerveld, Soenita S Goerdayal, Elisabetta Argenzio, Metello Innocenti

J Proteome Res· December 2016

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New nuclear and perinuclear functions of formins.
Tadamoto Isogai, Metello Innocenti

Biochem Soc Trans· December 2016

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PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins.
Daniela Leyton-Puig, Katarzyna M Kedziora, Tadamoto Isogai, Bram van den Broek, Kees Jalink, Metello Innocenti

Biol Open· July 2016

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Invadosomes - shaping actin networks to follow mechanical cues.
Katarzyna M Kedziora, Tadamoto Isogai, Kees Jalink, Metello Innocenti

Front Biosci (Landmark Ed)· June 2016

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Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases.
Katarzyna M Kedziora, Daniela Leyton-Puig, Elisabetta Argenzio, Anja J Boumeester, Bram van Butselaar, Metello Innocenti

J Biol Chem· February 2016

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Initiation of lamellipodia and ruffles involves cooperation between mDia1 and the Arp2/3 complex.
Tadamoto Isogai, Rob van der Kammen, Daniela Leyton-Puig, Katarzyna M Kedziora, Kees Jalink, Metello Innocenti

J Cell Sci· October 2015

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Proteomic analyses uncover a new function and mode of action for mouse homolog of Diaphanous 2 (mDia2).
Tadamoto Isogai, Rob van der Kammen, Soenita S Goerdayal, Albert J R Heck, A F Maarten Altelaar, Metello Innocenti

Mol Cell Proteomics· April 2015

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SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton.
Tadamoto Isogai, Rob van der Kammen, Metello Innocenti

Sci Rep· April 2015

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Interplay between N-WASP and CK2 optimizes clathrin-mediated endocytosis of EGFR.
Magda Galovic, Dalu Xu, Liliana Beatriz Areces, Rob van der Kammen, Metello Innocenti

J Cell Sci· June 2011

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