Publications by authors named "Michael Berna"

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Bioanalytical approaches to support the development of antibody-oligonucleotide conjugate (AOC) therapeutic proteins.
Anthony Murphy, Ryan Hill, Michael Berna

Xenobiotica· August 2024

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A Cross Company Perspective on the Assessment of Therapeutic Protein Biotransformation.
Markus Walles, Michael Berna, Wenying Jian, Simon Hauri, Shawna Hengel

Drug Metab Dispos· June 2022

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Quantitative characterization of the mechanism of action and impact of a 'proteolysis-permitting' anti-PCSK9 antibody.
Ryan J Hansen, Michael J Berna, Andrea E Sperry, Thomas P Beyer, Victor J Wroblewski

MAbs· November 2017

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Characterization and quantification of oxyntomodulin in human and rat plasma using high-resolution accurate mass LC-MS.
Jennifer M Cox, Michael J Berna, Zhaoyan Jin, Amy L Cox, Kyle W Sloop

Bioanalysis· August 2016

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The interactome of the atypical phosphatase Rtr1 in Saccharomyces cerevisiae.
Whitney R Smith-Kinnaman, Michael J Berna, Gerald O Hunter, Jason D True, Peter Hsu

Mol Biosyst· July 2014

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Current applications of liquid chromatography/mass spectrometry in pharmaceutical discovery after a decade of innovation.
Bradley L Ackermann, Michael J Berna, James A Eckstein, Lee W Ott, Ajai K Chaudhary

Annu Rev Anal Chem (Palo Alto Calif)· October 2010

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Detection of left ventricular hypertrophy in rats administered a peroxisome proliferator-activated receptor alpha/gamma dual agonist using natriuretic peptides and imaging.
Steven K Engle, Philip F Solter, Kelly M Credille, Christopher M Bull, Stephanie Adams, Michael J Berna

Toxicol Sci· April 2010

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Increased throughput for low-abundance protein biomarker verification by liquid chromatography/tandem mass spectrometry.
Michael Berna, Bradley Ackermann

Anal Chem· May 2009

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Quantification of NTproBNP in rat serum using immunoprecipitation and LC/MS/MS: a biomarker of drug-induced cardiac hypertrophy.
Michael Berna, Lee Ott, Steve Engle, David Watson, Philip Solter

Anal Chem· February 2008

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Quantification of heart fatty acid binding protein as a biomarker for drug-induced cardiac and musculoskeletal necroses.
Eugene Y Zhen, Michael J Berna, Zhaoyan Jin, Michael L Pritt, David E Watson

Proteomics Clin Appl· July 2007

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Strategic use of immunoprecipitation and LC/MS/MS for trace-level protein quantification: myosin light chain 1, a biomarker of cardiac necrosis.
Michael J Berna, Yuejun Zhen, David E Watson, John E Hale, Bradley L Ackermann

Anal Chem· June 2007

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Coupling immunoaffinity techniques with MS for quantitative analysis of low-abundance protein biomarkers.
Bradley L Ackermann, Michael J Berna

Expert Rev Proteomics· April 2007

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Quantification of serine enantiomers in rat brain microdialysate using Marfey's reagent and LC/MS/MS.
Michael J Berna, Bradley L Ackermann

J Chromatogr B Analyt Technol Biomed Life Sci· February 2007

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Quantitative analysis of amyloid beta peptides in cerebrospinal fluid of Alzheimer's disease patients by immunoaffinity purification and stable isotope dilution liquid chromatography/negative electrospray ionization tandem mass spectrometry.
Tomoyuki Oe, Bradley L Ackermann, Koichi Inoue, Michael J Berna, Carlos O Garner

Rapid Commun Mass Spectrom· January 2007

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Online immunoaffinity liquid chromatography/tandem mass spectrometry determination of a type II collagen peptide biomarker in rat urine: Investigation of the impact of collision-induced dissociation fluctuation on peptide quantitation.
Michael Berna, Chris Schmalz, Kevin Duffin, Peter Mitchell, Mark Chambers

Anal Biochem· September 2006

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Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor.
Amy C Porter, John-Michael Sauer, Michael D Knierman, Gerald W Becker, Michael J Berna

J Pharmacol Exp Ther· June 2002

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Effects of flow rate on high-throughput quantitative analysis of protein-precipitated plasma using liquid chromatography/tandem mass spectrometry.
Anthony T Murphy, Michael J Berna, Jeffrey L Holsapple, Bradley L Ackermann

Rapid Commun Mass Spectrom· April 2002

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Recent advances in use of LC/MS/MS for quantitative high-throughput bioanalytical support of drug discovery.
Bradley L Ackermann, Michael J Berna, Anthony T Murphy

Curr Top Med Chem· January 2002

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