Publications by authors named "Michael C Hutter"

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Corrigendum to: "New CYP154C4 from Streptomyces cavourensis YBQ59 performs regio- and stereo-selective 3β-hydroxylation of nootkatone" [Arch. Biochem. Biophys. 762 (2024) 110192].
Thuy T B Ly, Thu-Thuy Thi Mai, Alessandra Raffaele, Vlada B Urlacher, Thi Thao Nguyen, Michael C Hutter

Arch Biochem Biophys· September 2025

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Functional analysis of CYP4B1 enzymes from apes and humans uncovers evolutionary hot spots for adaptations of the catalytical function.
Saskia Hüsken, Annika Röder, Johannes Ptok, Anne E Meyer, Mats Georg, Michael C Hutter

PLoS Genet· June 2025

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New CYP154C4 from Streptomyces cavourensis YBQ59 performs regio- and stereo- selective 3β-hydroxlation of nootkatone.
Thuy T B Ly, Thu-Thuy Thi Mai, Alessandra Raffaele, Vlada B Urlacher, Thi Thao Nguyen, Michael C Hutter

Arch Biochem Biophys· December 2024

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High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of .
Sandra Johannsen, Robin M Gierse, Arne Krüger, Rachel L Edwards, Vittoria Nanna, Michael C Hutter

ACS Infect Dis· March 2024

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Spotlight on CYP4B1.
Annika Röder, Saskia Hüsken, Michael C Hutter, Allan E Rettie, Helmut Hanenberg

Int J Mol Sci· January 2023

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Differential Multimolecule Fingerprint for Similarity Search─Making Use of Active and Inactive Compound Sets in Virtual Screening.
Michael C Hutter

J Chem Inf Model· June 2022

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Resurrection and characterization of ancestral CYP11A1 enzymes.
Philip Hartz, Silja J Strohmaier, Basma M El-Gayar, Ammar Abdulmughni, Michael C Hutter

FEBS J· November 2021

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Metabolism of oral turinabol by the human brain cholesterol 24-hydroxylase CYP46A1.
Natalia Putkaradze, Philip Hartz, Michael C Hutter, Josef Zapp, Mario Thevis

J Steroid Biochem Mol Biol· September 2021

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Molecular evolution of a cytochrome P450 for the synthesis of potential antidepressant (2R,6R)-hydroxynorketamine.
Ansgar Bokel, Michael C Hutter, Vlada B Urlacher

Chem Commun (Camb)· January 2021

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Identification and circumvention of bottlenecks in CYP21A2-mediated premedrol production using recombinant Escherichia coli.
Lisa König, Simone Brixius-Anderko, Mohammed Milhim, Daniela Tavouli-Abbas, Michael C Hutter

Biotechnol Bioeng· April 2020

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Highly regio- and stereoselective hydroxylation of vitamin D2 by CYP109E1.
Natalia Putkaradze, Lisa König, Lars Kattner, Michael C Hutter, Rita Bernhardt

Biochem Biophys Res Commun· April 2020

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Novel insights into oxidation of fatty acids and fatty alcohols by cytochrome P450 monooxygenase CYP4B1.
Florian A Thesseling, Michael C Hutter, Constanze Wiek, John P Kowalski, Allan E Rettie

Arch Biochem Biophys· January 2020

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Conservation and Relevance of Pharmacophore Point Types.
Tobias Fehlmann, Michael C Hutter

J Chem Inf Model· April 2019

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CYP109E1 from Bacillus megaterium Acts as a 24- and 25-Hydroxylase for Cholesterol.
Natalia Putkaradze, Martin Litzenburger, Michael Christopher Hutter, Rita Bernhardt

Chembiochem· March 2019

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Novel approach to improve progesterone hydroxylation selectivity by CYP106A2 via rational design of adrenodoxin binding.
Tanja Sagadin, Jan Riehm, Natalia Putkaradze, Michael C Hutter, Rita Bernhardt

FEBS J· March 2019

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The current limits in virtual screening and property prediction.
Michael C Hutter

Future Med Chem· July 2018

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Ask the experts: computational chemistry.
Chérif F Matta, Michael C Hutter

Future Med Chem· July 2018

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Foreword: computational special focus issue.
Chérif F Matta, Michael C Hutter

Future Med Chem· July 2018

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Binding modes of CYP106A2 redox partners determine differences in progesterone hydroxylation product patterns.
Tanja Sagadin, Jan L Riehm, Mohammed Milhim, Michael C Hutter, Rita Bernhardt

Commun Biol· July 2018

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Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone.
Yogan Khatri, Ilona K Jóźwik, Michael Ringle, Irina Alexandra Ionescu, Martin Litzenburger, Michael Christopher Hutter

ACS Chem Biol· April 2018

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Engineering of versatile redox partner fusions that support monooxygenase activity of functionally diverse cytochrome P450s.
Patrick J Bakkes, Jan L Riehm, Tanja Sagadin, Ansgar Rühlmann, Peter Schubert, Michael C Hutter

Sci Rep· August 2017

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Biotransformation of prednisone and dexamethasone by cytochrome P450 based systems - Identification of new potential drug candidates.
Natalia Putkaradze, Flora Marta Kiss, Daniela Schmitz, Josef Zapp, Michael C Hutter

J Biotechnol· January 2017

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Regioselective Acetylation of C21 Hydroxysteroids by the Bacterial Chloramphenicol Acetyltransferase I.
Azzam Mosa, Michael C Hutter, Josef Zapp, Rita Bernhardt, Frank Hannemann

Chembiochem· July 2015

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Mechanistic details for anthraniloyl transfer in PqsD: the initial step in HHQ biosynthesis.
Michael C Hutter, Christian Brengel, Matthias Negri, Claudia Henn, Christina Zimmer

J Mol Model· June 2014

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Batch tautomer generation with MolTPC.
Thorsten Will, Michael C Hutter, Johann Jauch, Volkhard Helms

J Comput Chem· October 2013

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