Publications by authors named "Michael Cynamon"

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Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against and Malaria Parasites.
Marianna Stampolaki, Satish R Malwal, Nadine Alvarez-Cabrera, Zijun Gao, Mohammad Moniruzzaman, Michael H Cynamon

ACS Infect Dis· February 2023

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Culture-Free Enumeration of in Mouse Tissues Using the Molecular Bacterial Load Assay for Preclinical Drug Development.
Dimitrios Evangelopoulos, Carolyn M Shoen, Isobella Honeyborne, Simon Clark, Ann Williams, Michael H Cynamon

Microorganisms· February 2022

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Repurposing Avermectins and Milbemycins against and Other Nontuberculous Mycobacteria.
Lara Muñoz-Muñoz, Carolyn Shoen, Gaye Sweet, Asunción Vitoria, Tim J Bull, Michael Cynamon

Antibiotics (Basel)· April 2021

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Developing Tadpole as a Comparative Animal Model to Study Pathogenicity.
Arianna Lopez, Carolyn Shoen, Michael Cynamon, Dionysia Dimitrakopoulou, Matthieu Paiola

Int J Mol Sci· January 2021

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A polymeric approach toward resistance-resistant antimicrobial agent with dual-selective mechanisms of action.
Silei Bai, Jianxue Wang, Kailing Yang, Cailing Zhou, Yangfan Xu, Michael Cynamon

Sci Adv· January 2021

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Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.
Behnoush Hajian, Eric Scocchera, Carolyn Shoen, Jolanta Krucinska, Kishore Viswanathan, Michael Cynamon

Cell Chem Biol· June 2019

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Activities of Omadacycline against Rapidly Growing Mycobacteria.
Carolyn Shoen, David Benaroch, Mary Sklaney, Michael Cynamon

Antimicrob Agents Chemother· May 2019

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Advancing Translational Science for Pulmonary Nontuberculous Mycobacterial Infections. A Road Map for Research.
Shelby Daniel-Wayman, Getahun Abate, Daniel L Barber, Luiz E Bermudez, Rhea N Coler, Michael H Cynamon

Am J Respir Crit Care Med· April 2019

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Modeling the HIV-1 Antiretroviral Therapeutic Drug Interaction.
Ernest N Damianopoulos, Michael Cynamon

AIDS Res Hum Retroviruses· December 2018

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A call to arms: Unifying the fight against resistance.
Alexis Kaushansky, Lizbeth Hedstrom, Aaron Goldman, Juswinder Singh, Priscilla L Yang, Michael Cynamon

Sci Signal· October 2018

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Therapy for Infection: Beyond 2018.
Michelle S DeStefano, Carolyn M Shoen, Michael H Cynamon

Front Microbiol· September 2018

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and Activities of Contezolid (MRX-I) against Mycobacterium tuberculosis.
Carolyn Shoen, Michelle DeStefano, Barry Hafkin, Michael Cynamon

Antimicrob Agents Chemother· August 2018

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2-N-Arylthiazole inhibitors of Mycobacterium tuberculosis.
Michael P Clark, Tiansheng Wang, Emanuele Perola, David D Deininger, Harmon J Zuccola, Michael H Cynamon

Bioorg Med Chem Lett· September 2017

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Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis.
Behnoush Hajian, Eric Scocchera, Santosh Keshipeddy, Narendran G-Dayanandan, Carolyn Shoen, Michael Cynamon

PLoS One· July 2017

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In vitro activity of a novel compound, Mul-1867, against clinically significant fungi Candida spp. and Aspergillus spp.
George Tetz, Michael Cynamon, Gregory Hendricks, Daria Vikina, Victor Tetz

Int J Antimicrob Agents· July 2017

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Antiinfectives targeting enzymes and the proton motive force.
Xinxin Feng, Wei Zhu, Lici A Schurig-Briccio, Steffen Lindert, Carolyn Shoen, Michael Cynamon

Proc Natl Acad Sci U S A· December 2015

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Oxa, Thia, Heterocycle, and Carborane Analogues of SQ109: Bacterial and Protozoal Cell Growth Inhibitors.
Kai Li, Yang Wang, Gyongseon Yang, Sooyoung Byun, Guodong Rao, Michael Cynamon

ACS Infect Dis· May 2015

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Clinical isolates of Candida albicans, Candida tropicalis, and Candida krusei have different susceptibilities to Co(II) and Cu(II) complexes of 1,10-phenanthroline.
Amanda E Hoffman, Leann Miles, Tiffany J Greenfield, Carolyn Shoen, Michelle DeStefano, Michael Cynamon

Biometals· April 2015

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A novel inhibitor of gyrase B is a potent drug candidate for treatment of tuberculosis and nontuberculosis mycobacterial infections.
Christopher P Locher, Steven M Jones, Brian L Hanzelka, Emanuele Perola, Carolyn M Shoen, Michael H Cynamon

Antimicrob Agents Chemother· March 2015

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The efflux pump inhibitor timcodar improves the potency of antimycobacterial agents.
Trudy H Grossman, Carolyn M Shoen, Steven M Jones, Peter L Jones, Michael H Cynamon

Antimicrob Agents Chemother· March 2015

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Co(II) and Cu(II) pyrophosphate complexes have selectivity and potency against Mycobacteria including Mycobacterium tuberculosis.
Amanda E Hoffman, Michelle DeStefano, Carolyn Shoen, Krishnamoorthy Gopinath, Digby F Warner, Michael Cynamon

Eur J Med Chem· September 2014

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Metabolic and bactericidal effects of targeted suppression of NadD and NadE enzymes in mycobacteria.
Irina A Rodionova, Brian M Schuster, Kristine M Guinn, Leonardo Sorci, David A Scott, Michael Cynamon

mBio· February 2014

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Inhibition of mycobacterial alanine racemase activity and growth by thiadiazolidinones.
Yashang Lee, Sara Mootien, Carolyn Shoen, Michelle Destefano, Pier Cirillo, Michael H Cynamon

Biochem Pharmacol· July 2013

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A Modified Bacillus Calmette-Guérin (BCG) Vaccine with Reduced Activity of Antioxidants and Glutamine Synthetase Exhibits Enhanced Protection of Mice despite Diminished in Vivo Persistence.
Carolyn M Shoen, Michelle S DeStefano, Cynthia C Hager, Kyi-Toe Tham, Miriam Braunstein, Michael H Cynamon

Vaccines (Basel)· January 2013

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In vitro activity of TP-271 against Mycobacterium abscessus, Mycobacterium fortuitum, and Nocardia species.
Michael Cynamon, Jeff Jureller, Balaji Desai, Krithika Ramachandran, Mary Sklaney

Antimicrob Agents Chemother· July 2012

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