Publications by authors named "Pier Cirillo"

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Inhibition of Macrophage Migration Inhibitory Factor by a Chimera of Two Allosteric Binders.
Pier F Cirillo, Oluwatoyin A Asojo, Uday Khire, Yashang Lee, Sara Mootien

ACS Med Chem Lett· October 2020

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Selective CB2 receptor agonists. Part 1: the identification of novel ligands through computer-aided drug design (CADD) approaches.
Eugene R Hickey, Renee Zindell, Pier F Cirillo, Lifen Wu, Monika Ermann

Bioorg Med Chem Lett· February 2015

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Selective CB2 receptor agonists. Part 3: the optimization of a piperidine-based series that demonstrated efficacy in an in vivo neuropathic pain model.
Alessandra Bartolozzi, Pier Francesco Cirillo, Angela K Berry, Eugene R Hickey, David S Thomson

Bioorg Med Chem Lett· February 2015

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Inhibition of mycobacterial alanine racemase activity and growth by thiadiazolidinones.
Yashang Lee, Sara Mootien, Carolyn Shoen, Michelle Destefano, Pier Cirillo

Biochem Pharmacol· July 2013

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A novel allosteric inhibitor of macrophage migration inhibitory factor (MIF).
Fengwei Bai, Oluwatoyin A Asojo, Pier Cirillo, Mihai Ciustea, Michel Ledizet

J Biol Chem· August 2012

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Thiadiazolidinones: a new class of alanine racemase inhibitors with antimicrobial activity against methicillin-resistant Staphylococcus aureus.
Mihai Ciustea, Sara Mootien, Adriana E Rosato, Oriana Perez, Pier Cirillo

Biochem Pharmacol· February 2012

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1,4-Diazepane compounds as potent and selective CB2 agonists: optimization of metabolic stability.
Doris Riether, Lifen Wu, Pier F Cirillo, Angela Berry, Edward R Walker

Bioorg Med Chem Lett· April 2011

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Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors.
Pier F Cirillo, Eugene R Hickey, Neil Moss, Steffen Breitfelder, Raj Betageri

Bioorg Med Chem Lett· May 2009

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New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site.
Neil Moss, Steffen Breitfelder, Raj Betageri, Pier F Cirillo, Tazmeen Fadra

Bioorg Med Chem Lett· August 2007

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Structure-activity relationships of the p38alpha MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796).
John Regan, Alison Capolino, Pier F Cirillo, Thomas Gilmore, Anne G Graham

J Med Chem· October 2003

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The kinetics of binding to p38MAP kinase by analogues of BIRB 796.
John Regan, Christopher A Pargellis, Pier F Cirillo, Thomas Gilmore, Eugene R Hickey

Bioorg Med Chem Lett· September 2003

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The non-diaryl heterocycle classes of p38 MAP kinase inhibitors.
Pier F Cirillo, Christopher Pargellis, John Regan

Curr Top Med Chem· September 2002

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Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate.
John Regan, Steffen Breitfelder, Pier Cirillo, Thomas Gilmore, Anne G Graham

J Med Chem· July 2002

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Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site.
Christopher Pargellis, Liang Tong, Laurie Churchill, Pier F Cirillo, Thomas Gilmore

Nat Struct Biol· April 2002

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