Publications by authors named "Michael D Bobardt"

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Astodrimer sodium nasal spray forms a barrier to SARS-CoV-2 in vitro and preserves normal mucociliary function in human nasal epithelium.
Jeremy R A Paull, Carolyn A Luscombe, Aynaz Seta, Graham P Heery, Michael D Bobardt

Sci Rep· September 2024

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A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents.
Thuc Nguyen Dan Do, Kim Donckers, Laura Vangeel, Arnab K Chatterjee, Philippe A Gallay, Michael D Bobardt

Antiviral Res· August 2021

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Protective Effects of Astodrimer Sodium 1% Nasal Spray Formulation against SARS-CoV-2 Nasal Challenge in K18-hACE2 Mice.
Jeremy R A Paull, Carolyn A Luscombe, Alex Castellarnau, Graham P Heery, Michael D Bobardt

Viruses· August 2021

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Virucidal and antiviral activity of astodrimer sodium against SARS-CoV-2 in vitro.
Jeremy R A Paull, Graham P Heery, Michael D Bobardt, Alex Castellarnau, Carolyn A Luscombe

Antiviral Res· July 2021

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Characterization of the Anti-HCV Activities of the New Cyclophilin Inhibitor STG-175.
Philippe A Gallay, Udayan Chatterji, Michael D Bobardt, Zhengyu Long, Shengli Zhang

PLoS One· March 2017

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The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action.
Philippe A Gallay, Michael D Bobardt, Udayan Chatterji, Daniel J Trepanier, Daren Ure

PLoS One· May 2016

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HCV core residues critical for infectivity are also involved in core-NS5A complex formation.
Katarzyna Gawlik, James Baugh, Udayan Chatterji, Precious J Lim, Michael D Bobardt

PLoS One· January 2015

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Correlation of naturally occurring HIV-1 resistance to DEB025 with capsid amino acid polymorphisms.
Philippe A Gallay, Roger G Ptak, Michael D Bobardt, Jean-Maurice Dumont, Grégoire Vuagniaux

Viruses· March 2013

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Sustained local delivery of structurally diverse HIV-1 microbicides released from sublimation enthalpy controlled matrices.
Simi Gunaseelan, Philippe A Gallay, Michael D Bobardt, Charlene S Dezzutti, Timothy Esch

Pharm Res· November 2012

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HSV neutralization by the microbicidal candidate C5A.
Lot de Witte, Michael D Bobardt, Udayan Chatterji, Freek B van Loenen, Georges M G M Verjans

PLoS One· May 2011

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Syndecan-Fc hybrid molecule as a potent in vitro microbicidal anti-HIV-1 agent.
Michael D Bobardt, Udayan Chatterji, Lana Schaffer, Lot de Witte, Philippe A Gallay

Antimicrob Agents Chemother· July 2010

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HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors.
Udayan Chatterji, Precious Lim, Michael D Bobardt, Stefan Wieland, Daniel G Cordek

J Hepatol· July 2010

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Cyclophilin A-independent recruitment of NS5A and NS5B into hepatitis C virus replication complexes.
Udayan Chatterji, Michael D Bobardt, Precious Lim, Philippe A Gallay

J Gen Virol· May 2010

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Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent.
Roger G Ptak, Philippe A Gallay, Dirk Jochmans, Andrew P Halestrap, Urs T Ruegg, Michael D Bobardt

Antimicrob Agents Chemother· April 2008

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Hepatitis C virus NS5A anchor peptide disrupts human immunodeficiency virus.
Michael D Bobardt, Guofeng Cheng, Lot de Witte, Suganya Selvarajah, Udayan Chatterji

Proc Natl Acad Sci U S A· April 2008

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Cell-free human immunodeficiency virus type 1 transcytosis through primary genital epithelial cells.
Michael D Bobardt, Udayan Chatterji, Suganya Selvarajah, Bernadette Van der Schueren, Guido David

J Virol· January 2007

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Trim5alpha accelerates degradation of cytosolic capsid associated with productive HIV-1 entry.
Udayan Chatterji, Michael D Bobardt, Peter Gaskill, Dennis Sheeter, Howard Fox

J Biol Chem· December 2006

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Naturally occurring capsid substitutions render HIV-1 cyclophilin A independent in human cells and TRIM-cyclophilin-resistant in Owl monkey cells.
Udayan Chatterji, Michael D Bobardt, Robyn Stanfield, Roger G Ptak, Luke A Pallansch

J Biol Chem· December 2005

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A highly conserved arginine in gp120 governs HIV-1 binding to both syndecans and CCR5 via sulfated motifs.
Aymeric de Parseval, Michael D Bobardt, Anju Chatterji, Udayan Chatterji, John H Elder

J Biol Chem· November 2005

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Effect of polyanion-resistance on HIV-1 infection.
Michael D Bobardt, Mercedes Armand-Ugón, Imma Clotet, Zhe Zhang, Guido David

Virology· August 2004

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Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion.
Michael D Bobardt, Patrick Salmon, Lianchun Wang, Jeffrey D Esko, Dana Gabuzda

J Virol· June 2004

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Syndecan captures, protects, and transmits HIV to T lymphocytes.
Michael D Bobardt, Andrew C S Saphire, Hsiu-Cheng Hung, Xiaocong Yu, Bernadette Van der Schueren

Immunity· January 2003

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Cyclophilin a plays distinct roles in human immunodeficiency virus type 1 entry and postentry events, as revealed by spinoculation.
Andrew C S Saphire, Michael D Bobardt, Philippe A Gallay

J Virol· May 2002

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trans-Complementation rescue of cyclophilin A-deficient viruses reveals that the requirement for cyclophilin A in human immunodeficiency virus type 1 replication is independent of its isomerase activity.
Andrew C S Saphire, Michael D Bobardt, Philippe A Gallay

J Virol· March 2002

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