Publications by authors named "Robyn Stanfield"

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Rational design of next-generation filovirus vaccines combining glycoprotein stabilization and nanoparticle display with glycan modification.
Yi-Zong Lee, Yi-Nan Zhang, Maddy L Newby, Garrett Ward, Keegan Braz Gomes, Robyn L Stanfield

Nat Commun· December 2025

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The conserved bridging domain on HCV E1E2 glycoprotein complex is targeted by neutralizing antibodies from diverse lineages.
Fang Chen, Yen Thi Kim Nguyen, Yi-Zong Lee, Erick Giang, Sing Chau Lau, Robyn L Stanfield

bioRxiv· November 2025

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Using phage display for rational engineering of a higher-affinity humanized 3' phosphohistidine-specific antibody.
Gregory D Martyn, Rajasree Kalagiri, Gianluca Veggiani, Robyn L Stanfield, Indrani Choudhuri

Commun Chem· November 2025

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Structural and genetic signatures of two classes of HCV E2 neutralizing face antibodies from non-human primates immunized with a recombinant E1E2.
Yen T K Nguyen, Fang Chen, Erick Giang, Swati Saha, Lynn A Ueno, Robyn Stanfield

bioRxiv· October 2025

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Rational design of next-generation filovirus vaccines through glycoprotein stabilization, nanoparticle display, and glycan modification.
Yi-Zong Lee, Yi-Nan Zhang, Maddy L Newby, Garrett Ward, Keegan Braz Gomes, Robyn L Stanfield

bioRxiv· August 2025

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Origin of immunoglobulins and T cell receptors: A candidate gene for invasion by the RAG transposon.
Martin F Flajnik, Robyn L Stanfield, Ana Verissimo, Harold R Neely, Antonio Muñoz-Mérida

Sci Adv· July 2025

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Cladophorol-A is an inhibitor of cyclic GMP-AMP synthase.
Mildred Kissai, Emily N Chin, Francisco Martínez-Peña, Ariana Sulpizio, E Paige Stout, Robyn L Stanfield

Bioorg Med Chem Lett· January 2025

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Discovery of Potent and Selective Pyridone-Based Small Molecule Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains.
Oren L Lederberg, Nicholas L Yan, Julian Sanchez, Wen Ren, Carl Ash, Robyn L Stanfield

J Med Chem· December 2024

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Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Yi-Zong Lee, Jerome Han, Yi-Nan Zhang, Garrett Ward, Keegan Braz Gomes, Robyn L Stanfield

Nat Commun· November 2024

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Using phage display for rational engineering of a higher affinity humanized 3' phosphohistidine-specific antibody.
Gregory D Martyn, Rajasree Kalagiri, Gianluca Veggiani, Robyn L Stanfield, Indrani Choudhuri

bioRxiv· November 2024

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Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer.
Xun Sun, James A Ferguson, Ke Yang, Robyn L Stanfield, H Jane Dyson

Protein Sci· September 2024

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Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Pilar X Altman, Gabriel Ozorowski, Robyn L Stanfield, Jeremy Haakenson, Michael Appel

PLoS Pathog· September 2024

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Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer.
Xun Sun, James A Ferguson, Ke Yang, Robyn L Stanfield, H Jane Dyson

bioRxiv· March 2024

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A tale of two fusion proteins: understanding the metastability of human respiratory syncytial virus and metapneumovirus and implications for rational design of uncleaved prefusion-closed trimers.
Yi-Zong Lee, Jerome Han, Yi-Nan Zhang, Garrett Ward, Keegan Braz Gomes, Robyn L Stanfield

bioRxiv· March 2024

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Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Pilar X Altman, Gabriel Ozorowski, Robyn L Stanfield, Jeremy Haakenson, Michael Appel

bioRxiv· February 2024

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Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant.
Xun Sun, James A Ferguson, Benjamin I Leach, Robyn L Stanfield, H Jane Dyson

J Am Chem Soc· January 2024

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An Ancient MHC-Linked Gene Encodes a Nonrearranging Shark Antibody, UrIg, Convergent with IgG.
Martin F Flajnik, Robyn Stanfield, Elena N Pokidysheva, Sergei P Boudko, Ian Wilson

J Immunol· September 2023

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The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Ruiqi Huang, Gabrielle Warner Jenkins, Yunjeong Kim, Robyn L Stanfield, Amrinder Singh

Proc Natl Acad Sci U S A· September 2023

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Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Laetitia Misson Mindrebo, Hejun Liu, Gabriel Ozorowski, Quoc Tran, Jordan Woehl, Robyn L Stanfield

Proc Natl Acad Sci U S A· June 2023

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Divergent Total Synthesis and Characterization of Maxamycins.
Maxwell J Moore, Pengjin Qin, D Jamin Keith, Zhi-Chen Wu, Sunna Jung, Robyn L Stanfield

J Am Chem Soc· June 2023

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Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer.
Jelle van Schooten, Anna Schorcht, Elinaz Farokhi, Jeffrey C Umotoy, Hongmei Gao, Robyn L Stanfield

PLoS Pathog· November 2022

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Author Correction: Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines.
Linling He, Anshul Chaudhary, Xiaohe Lin, Cindy Sou, Tanwee Alkutkar, Robyn L Stanfield

Nat Commun· October 2022

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Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.
Jelle van Schooten, Elinaz Farokhi, Anna Schorcht, Tom L G M van den Kerkhof, Hongmei Gao, Robyn L Stanfield

Nat Commun· August 2022

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The molecular basis of allostery in a facilitated dissociation process.
Francis D Appling, Rebecca B Berlow, Robyn L Stanfield, H Jane Dyson, Peter E Wright

Structure· December 2021

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