Publications by authors named "Michael D Scholle"

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A duplexed high-throughput mass spectrometry assay for bifunctional POLB polymerase and lyase activity.
Zachary A Gurard-Levin, Brian McMillan, Douglas A Whittington, Brian Doyon, Michael D Scholle

SLAS Technol· October 2024

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Label-free duplex SAMDI-MS screen reveals novel SARS-CoV-2 3CLpro inhibitors.
Michael D Scholle, Patrick T O'Kane, Sandra Dib, Zachary A Gurard-Levin

Antiviral Res· April 2022

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High-Throughput Affinity Selection Mass Spectrometry Using SAMDI-MS to Identify Small-Molecule Binders of the Human Rhinovirus 3C Protease.
Michael D Scholle, Doug McLaughlin, Zachary A Gurard-Levin

SLAS Discov· September 2021

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Development of a Novel Label-Free and High-Throughput Arginase-1 Assay Using Self-Assembled Monolayer Desorption Ionization Mass Spectrometry.
Michael D Scholle, Zachary A Gurard-Levin

SLAS Discov· July 2021

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Label-Free Screening of SARS-CoV-2 NSP14 Exonuclease Activity Using SAMDI Mass Spectrometry.
Michael D Scholle, Cheng Liu, Jerome Deval, Zachary A Gurard-Levin

SLAS Discov· July 2021

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Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development.
Cheng Liu, Sandro Boland, Michael D Scholle, Dorothee Bardiot, Arnaud Marchand

Antiviral Res· March 2021

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Evaluation of SARS-CoV-2 3C-like protease inhibitors using self-assembled monolayer desorption ionization mass spectrometry.
Zachary A Gurard-Levin, Cheng Liu, Andreas Jekle, Ruchika Jaisinghani, Suping Ren, Michael D Scholle

Antiviral Res· October 2020

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A Mass Spectrometric Assay of METTL3/METTL14 Methyltransferase Activity.
Shane M Buker, Zachary A Gurard-Levin, Benjamin D Wheeler, Michael D Scholle, April W Case

SLAS Discov· April 2020

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Identification of Small-Molecule Noncovalent Binders Utilizing SAMDI Technology.
Erica C VanderPorten, Michael D Scholle, John Sherrill, John C Tran, Yichin Liu

SLAS Discov· December 2017

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Advances in MALDI Mass Spectrometry within Drug Discovery.
Dale S Cornett, Michael D Scholle

SLAS Discov· December 2017

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Active Site Metal Identity Alters Histone Deacetylase 8 Substrate Selectivity: A Potential Novel Regulatory Mechanism.
Carol Ann Castaneda, Jeffrey E Lopez, Caleb G Joseph, Michael D Scholle, Milan Mrksich

Biochemistry· October 2017

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Discovery of SIRT3 Inhibitors Using SAMDI Mass Spectrometry.
Kaushal Patel, John Sherrill, Milan Mrksich, Michael D Scholle

J Biomol Screen· August 2015

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A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening.
Tim J Wigle, Kerren K Swinger, John E Campbell, Michael D Scholle, John Sherrill

J Biomol Screen· July 2015

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The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites.
Alaa AbouElfetouh, Misty L Kuhn, Linda I Hu, Michael D Scholle, Dylan J Sorensen

Microbiologyopen· February 2015

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High-throughput screening of small molecule libraries using SAMDI mass spectrometry.
Zachary A Gurard-Levin, Michael D Scholle, Adam H Eisenberg, Milan Mrksich

ACS Comb Sci· July 2011

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Gcg-XTEN: an improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose.
Nathan C Geething, Wayne To, Benjamin J Spink, Michael D Scholle, Chia-wei Wang

PLoS One· April 2010

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A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner.
Volker Schellenberger, Chia-Wei Wang, Nathan C Geething, Benjamin J Spink, Andrew Campbell, Michael D Scholle

Nat Biotechnol· December 2009

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Peptide ligands specific to the oxidized form of Escherichia coli thioredoxin.
Michael D Scholle, Bridget S Banach, Samir M Hamdan, Charles C Richardson, Brian K Kay

Biochim Biophys Acta· November 2008

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Whole-genome detection of conditionally essential and dispensable genes in Escherichia coli via genetic footprinting.
Michael D Scholle, Svetlana Y Gerdes

Methods Mol Biol· June 2008

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Mapping protease substrates by using a biotinylated phage substrate library.
Michael D Scholle, Ushma Kriplani, Amanda Pabon, Kamakshi Sishtla, Marc J Glucksman

Chembiochem· May 2006

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Efficient construction of a large collection of phage-displayed combinatorial peptide libraries.
Michael D Scholle, John W Kehoe, Brian K Kay

Comb Chem High Throughput Screen· September 2005

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In vivo biotinylated proteins as targets for phage-display selection experiments.
Michael D Scholle, Frank R Collart, Brian K Kay

Protein Expr Purif· September 2004

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Molecular recognition properties of FN3 monobodies that bind the Src SH3 domain.
Ece Karatan, Matthew Merguerian, Zhaozhong Han, Michael D Scholle, Shohei Koide

Chem Biol· June 2004

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Accelerated screening of phage-display output with alkaline phosphatase fusions.
Zhaozhong Han, Ece Karatan, Michael D Scholle, John McCafferty, Brian K Kay

Comb Chem High Throughput Screen· February 2004

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Sequencing and characterization of pBM400 from Bacillus megaterium QM B1551.
Michael D Scholle, Christen A White, Muthusamy Kunnimalaiyaan, Patricia S Vary

Appl Environ Microbiol· November 2003

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