Publications by authors named "Michael Dyson"

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Biparatopic binding of ISB 1442 to CD38 in trans enables increased cell antibody density and increased avidity.
Jeremy Loyau, Thierry Monney, Marco Montefiori, Fedir Bokhovchuk, Jeremy Streuli, Michael Dyson

MAbs· December 2025

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ISB 2001 trispecific T cell engager shows strong tumor cytotoxicity and overcomes immune escape mechanisms of multiple myeloma cells.
Laura Carretero-Iglesia, Olivia J Hall, Jérémy Berret, Daniela Pais, Carole Estoppey, Michael R Dyson

Nat Cancer· October 2024

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Antibody and antibody fragments site-specific conjugation using new Q-tag substrate of bacterial transglutaminase.
Meddy El Alaoui, Eva Sivado, Anne-Catherine Jallas, Lamia Mebarki, Michael R Dyson

Cell Death Discov· February 2024

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Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies.
Mathieu Ferrari, Matteo Righi, Vania Baldan, Patrycja Wawrzyniecka, Anna Bulek, Michael Dyson

Nat Commun· February 2024

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Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries.
Michael R Dyson, Edward Masters, Deividas Pazeraitis, Rajika L Perera, Johanna L Syrjanen

MAbs· August 2021

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High-Throughput Expression Screening in Mammalian Suspension Cells.
Susan D Chapple, Michael R Dyson

Methods Mol Biol· March 2021

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A comprehensive search of functional sequence space using large mammalian display libraries created by gene editing.
Kothai Parthiban, Rajika L Perera, Maheen Sattar, Yanchao Huang, Sophie Mayle, Michael R Dyson

MAbs· July 2019

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Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?
Susan R Aungier, Alison J Cartwright, Anja Schwenzer, Jennifer L Marshall, Michael R Dyson

Ann Rheum Dis· February 2019

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Fundamentals of Expression in Mammalian Cells.
Michael R Dyson

Adv Exp Med Biol· September 2016

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Selection of Antibodies Interfering with Cell Surface Receptor Signaling Using Embryonic Stem Cell Differentiation.
Anna N Melidoni, Michael R Dyson, John McCafferty

Methods Mol Biol· August 2016

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Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2).
Salvatore Santamaria, Kazuhiro Yamamoto, Kenneth Botkjaer, Christopher Tape, Michael R Dyson

Biochem J· November 2015

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Expression screening in mammalian suspension cells.
Susan D Chapple, Michael R Dyson

Methods Mol Biol· June 2014

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Selecting antagonistic antibodies that control differentiation through inducible expression in embryonic stem cells.
Anna N Melidoni, Michael R Dyson, Sam Wormald, John McCafferty

Proc Natl Acad Sci U S A· October 2013

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Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells.
Ronny Falk, Anna Falk, Michael R Dyson, Anna N Melidoni, Kothai Parthiban

Methods· September 2012

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Detection of weak receptor-ligand interactions using IgM and J-chain-based fusion proteins.
Johannes U Ammann, Martin Jahnke, Michael R Dyson, Jim Kaufman, John Trowsdale

Eur J Immunol· May 2012

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Mapping protein interactions by combining antibody affinity maturation and mass spectrometry.
Michael R Dyson, Yong Zheng, Cunjie Zhang, Karen Colwill, Kritika Pershad

Anal Biochem· October 2011

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Molecular abnormalities in pediatric barrett esophagus: can we test for potential of neoplastic progression?
Edna L Maltby, Michael J Dyson, Mark R Wheeler, Mike Thomson, Chitra Sethuraman

Pediatr Dev Pathol· November 2010

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Selection of soluble protein expression constructs: the experimental determination of protein domain boundaries.
Michael R Dyson

Biochem Soc Trans· August 2010

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Mining mammalian genomes for folding competent proteins using Tat-dependent genetic selection in Escherichia coli.
Hyung-Kwon Lim, Thomas J Mansell, Stephen W Linderman, Adam C Fisher, Michael R Dyson

Protein Sci· December 2009

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Application of phage display to high throughput antibody generation and characterization.
Darren J Schofield, Anthony R Pope, Veronica Clementel, Jenny Buckell, Susan Dj Chapple, Michael R Dyson

Genome Biol· August 2008

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Identification of soluble protein fragments by gene fragmentation and genetic selection.
Michael R Dyson, Rajika L Perera, S Paul Shadbolt, Lynn Biderman, Krystyna Bromek

Nucleic Acids Res· May 2008

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Multiplexed expression and screening for recombinant protein production in mammalian cells.
Susan D J Chapple, Anna M Crofts, S Paul Shadbolt, John McCafferty, Michael R Dyson

BMC Biotechnol· December 2006

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Multiplex fluorescence in situ hybridization identifies novel rearrangements of chromosomes 6, 15, and 18 in primary uveal melanoma.
Karen Sisley, Nicola Tattersall, Michael Dyson, Kath Smith, Hardeep S Mudhar

Exp Eye Res· September 2006

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Production of soluble mammalian proteins in Escherichia coli: identification of protein features that correlate with successful expression.
Michael R Dyson, S Paul Shadbolt, Karen J Vincent, Rajika L Perera, John McCafferty

BMC Biotechnol· December 2004

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Detection of cryptic MLL insertions using a commercial dual-color fluorescence in situ hybridization probe.
Michael J Dyson, Polly J Talley, John T Reilly, David Stevenson, Emma Parsons

Cancer Genet Cytogenet· November 2003

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