Publications by authors named "Michael Hann"

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Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells.
Patrick J Brennan, Rebecca E Saunders, Mary Spanou, Sarah E Singleton, Marta Serafini, Michael M Hann

ACS Chem Biol· November 2025

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Correction: Emerging opportunities in the rewiring of biology through proximity inducing small molecules.
Michael M Hann

RSC Med Chem· October 2025

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Emerging opportunities in the rewiring of biology through proximity inducing small molecules.
Michael M Hann

RSC Med Chem· August 2025

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A Career Doing STUFF.
Michael M Hann

ChemMedChem· April 2025

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The continuing importance of chemical intuition for the medicinal chemist in the era of Artificial Intelligence.
Michael M Hann, György M Keserű

Expert Opin Drug Discov· February 2025

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Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells.
Patrick J Brennan, Rebecca E Saunders, Mary Spanou, Marta Serafini, Liang Sun, Michael M Hann

bioRxiv· March 2024

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Crystal structure and ligandability of the 14-3-3/pyrin interface.
Roxanne Lau, Michael M Hann, Christian Ottmann

Biochem Biophys Res Commun· April 2023

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Reactive fragments targeting carboxylate residues employing direct to biology, high-throughput chemistry.
Ross P Thomas, Emma K Grant, Eleanor R Dickinson, Francesca Zappacosta, Lee J Edwards, Michael M Hann

RSC Med Chem· April 2023

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Adapting the Cultural Formulation Interview for the Military.
Eric G Meyer, Ravi B DeSilva, Michael C Hann, Neil K Aggarwal, William L Brim

Psychiatr Serv· September 2022

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The PROTACtable genome.
Melanie Schneider, Chris J Radoux, Andrew Hercules, David Ochoa, Ian Dunham, Michael M Hann

Nat Rev Drug Discov· October 2021

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A direct-to-biology high-throughput chemistry approach to reactive fragment screening.
Ross P Thomas, Rachel E Heap, Francesca Zappacosta, Emma K Grant, Peter Pogány, Michael M Hann

Chem Sci· September 2021

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Lessons in Transcellular Membrane Transport Re-Learned.
Michael M Hann

J Pharm Sci· January 2021

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A Photoaffinity-Based Fragment-Screening Platform for Efficient Identification of Protein Ligands.
Emma K Grant, David J Fallon, Michael M Hann, Ken G M Fantom, Chad Quinn

Angew Chem Int Ed Engl· November 2020

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Early interventions in a US military FIRST episode psychosis program.
Michael C Hann, Evan Caporaso, George Loeffler, Adrian Cuellar, Lisa Herrington

Early Interv Psychiatry· December 2018

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Modulators of 14-3-3 Protein-Protein Interactions.
Loes M Stevers, Eline Sijbesma, Maurizio Botta, Carol MacKintosh, Tomas Obsil, Michael Hann

J Med Chem· May 2018

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Progressive renal insufficiency related to ALK inhibitor, alectinib.
Kojiro Nagai, Hiroyuki Ono, Motokazu Matsuura, Michael Hann, Sayo Ueda

Oxf Med Case Reports· April 2018

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Approaches to target tractability assessment - a practical perspective.
Kristin K Brown, Michael M Hann, Ami S Lakdawala, Rita Santos, Pamela J Thomas

Medchemcomm· April 2018

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Coupling the core of the anticancer drug etoposide to an oligonucleotide induces topoisomerase II-mediated cleavage at specific DNA sequences.
Lorena Infante Lara, Sabine Fenner, Steven Ratcliffe, Albert Isidro-Llobet, Michael Hann

Nucleic Acids Res· March 2018

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Influential factors on serum albumin concentration in hospitalized chronic kidney disease patients.
Sakiya Yoshimoto, Kojiro Nagai, Eriko Shibata, Sayo Ueda, Hiroyuki Ono, Michael Hann

J Med Invest· October 2017

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Stabilization of protein-protein interactions in drug discovery.
Sebastian A Andrei, Eline Sijbesma, Michael Hann, Jeremy Davis, Gavin O'Mahony

Expert Opin Drug Discov· September 2017

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What is the future for fragment-based drug discovery?
György M Keserű, Michael M Hann

Future Med Chem· September 2017

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Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery.
André Mateus, Laurie J Gordon, Gareth J Wayne, Helena Almqvist, Hanna Axelsson, Michael M Hann

Proc Natl Acad Sci U S A· July 2017

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The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis.
John Liddle, Benjamin Beaufils, Margaret Binnie, Anne Bouillot, Alexis A Denis, Michael M Hann

Bioorg Med Chem Lett· May 2017

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International trends in spice use: Prevalence, motivation for use, relationship to other substances, and perception of use and safety for synthetic cannabinoids.
George Loeffler, Eileen Delaney, Michael Hann

Brain Res Bull· September 2016

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Design Principles for Fragment Libraries: Maximizing the Value of Learnings from Pharma Fragment-Based Drug Discovery (FBDD) Programs for Use in Academia.
György M Keserű, Daniel A Erlanson, György G Ferenczy, Michael M Hann, Christopher W Murray

J Med Chem· September 2016

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