Publications by authors named "Michael Hugelshofer"

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Haptoglobin Attenuates Cerebrospinal Fluid Hemoglobin-Induced Neurological Deterioration in Sheep.
Bart R Thomson, Nina Schwendinger, Katrin Beckmann, Thomas Gentinetta, Daniel Couto, Michael Hugelshofer

Transl Stroke Res· June 2025

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Red Blood Cells in the Cerebrospinal Fluid Compartment After Subarachnoid Haemorrhage: Significance and Emerging Therapeutic Strategies.
Soham Bandyopadhyay, Nina Schwendinger, Behnam Rezai Jahromi, Shivanand P Lad, Spiros Blackburn, Michael Hugelshofer

Transl Stroke Res· February 2025

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C1-inhibitor to prevent intracerebral hemorrhage-related secondary brain injury.
Kevin Akeret, Bart R Thomson, Subhajit Ghosh, Marc Nolte, Urs Fischer, Michael Hugelshofer

Fluids Barriers CNS· November 2024

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OxyHbMeter-a novel bedside medical device for monitoring cell-free hemoglobin in the cerebrospinal fluid-proof of principle.
Nikolaos Tachatos, Jan Folkard Willms, Michael Sebastian Gerlt, Kiran Kuruvithadam, Michael Hugelshofer

Front Med Technol· April 2024

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Automated volumetric assessment of pituitary adenoma.
Raffaele Da Mutten, Olivier Zanier, Olga Ciobanu-Caraus, Stefanos Voglis, Michael Hugelshofer

Endocrine· January 2024

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Clinical potential of automated convolutional neural network-based hematoma volumetry after aneurysmal subarachnoid hemorrhage.
Bart R Thomson, Firat Gürlek, Raphael M Buzzi, Nina Schwendinger, Emanuela Keller, Michael Hugelshofer

J Stroke Cerebrovasc Dis· November 2023

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Rhinologic outcome of endoscopic transnasal-transsphenoidal pituitary surgery: an institutional series, systematic review, and meta-analysis.
Nathalie A Gstrein, Sebastian Zwicky, Carlo Serra, Michael Hugelshofer, Luca Regli

Eur Arch Otorhinolaryngol· September 2023

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Development and external validation of clinical prediction models for pituitary surgery.
Olivier Zanier, Matteo Zoli, Victor E Staartjes, Mohammed O Alalfi, Federica Guaraldi, Michael Hugelshofer

Brain Spine· August 2023

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Haptoglobin Treatment for Aneurysmal Subarachnoid Hemorrhage: Review and Expert Consensus on Clinical Translation.
Ian Galea, Soham Bandyopadhyay, Diederik Bulters, Rok Humar, Michael Hugelshofer

Stroke· July 2023

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Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity.
Bart R Thomson, Henning Richter, Kevin Akeret, Raphael M Buzzi, Vania Anagnostakou, Michael Hugelshofer

J Stroke Cerebrovasc Dis· March 2023

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MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral hemorrhage.
Kevin Akeret, Raphael M Buzzi, Bart R Thomson, Nina Schwendinger, Jan Klohs, Michael Hugelshofer

J Neuroinflammation· December 2022

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A model to visualize the fate of iron after intracranial hemorrhage using isotopic tracers and elemental bioimaging.
Patrick Bücker, Raphael M Buzzi, Kevin Akeret, Leila Mosberger, Henning Richter, Michael Hugelshofer

Metallomics· August 2022

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The HeMoVal study protocol: a prospective international multicenter cohort study to validate cerebrospinal fluid hemoglobin as a monitoring biomarker for aneurysmal subarachnoid hemorrhage related secondary brain injury.
Kevin Akeret, Raphael M Buzzi, Moritz Saxenhofer, Kathrin Bieri, Deborah Chiavi, Michael Hugelshofer

BMC Neurol· July 2022

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Spatial transcriptome data from coronal mouse brain sections after striatal injection of heme and heme-hemopexin.
Kevin Akeret, Michael Hugelshofer, Dominik J Schaer, Raphael M Buzzi

Data Brief· April 2022

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Spatial transcriptome analysis defines heme as a hemopexin-targetable inflammatoxin in the brain.
Raphael M Buzzi, Kevin Akeret, Nina Schwendinger, Jan Klohs, Florence Vallelian, Michael Hugelshofer

Free Radic Biol Med· February 2022

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Cerebrospinal fluid hemoglobin drives subarachnoid hemorrhage-related secondary brain injury.
Kevin Akeret, Raphael M Buzzi, Christian A Schaer, Bart R Thomson, Florence Vallelian, Michael Hugelshofer

J Cereb Blood Flow Metab· November 2021

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Modular Platform for the Development of Recombinant Hemoglobin Scavenger Biotherapeutics.
Raphael M Buzzi, Catherine M Owczarek, Kevin Akeret, Andrea Tester, Natasha Pereira, Michael Hugelshofer

Mol Pharm· August 2021

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Determining the Optimal Normalization Factor of Different Target Arteries for ex vivo Vascular Function Experiments: A New Standardized Procedure.
Michael Hugelshofer, Jeremy W Deuel, Raphael M Buzzi, Rok Humar, Dominik J Schaer

J Vasc Res· September 2020

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Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm.
Michael Hugelshofer, Raphael M Buzzi, Christian A Schaer, Henning Richter, Kevin Akeret

J Clin Invest· December 2019

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Natural Cerebral Aneurysm and Spontaneous Subarachnoid Hemorrhage in Mammals Other Than Man: Is There a Scope for Comparative Medicine?
Carl Muroi, Michael Hugelshofer, Frauke Seehusen, Emanuela Keller

World Neurosurg· February 2019

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Cell-Free Oxyhemoglobin in Cerebrospinal Fluid After Aneurysmal Subarachnoid Hemorrhage: Biomarker and Potential Therapeutic Target.
Michael Hugelshofer, Christopher M Sikorski, Martin Seule, Jeremy Deuel, Carl I Muroi

World Neurosurg· December 2018

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Endoscopic fenestration of intraventricular cerebrospinal fluid cysts: the contralateral approach.
Michael Hugelshofer, Nicolas Olmo Koechlin, Hani J Marcus, Ralf A Kockro, Robert Reisch

J Neurosurg· April 2016

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Patients' cosmetic satisfaction, pain, and functional outcomes after supraorbital craniotomy through an eyebrow incision.
Robert Reisch, Hani J Marcus, Michael Hugelshofer, Nicolas Olmo Koechlin, Axel Stadie

J Neurosurg· September 2014

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The impact of nonsteroidal anti-inflammatory drugs on inflammatory response after aneurysmal subarachnoid hemorrhage.
Carl Muroi, Michael Hugelshofer, Martin Seule, Emanuela Keller

Neurocrit Care· April 2014

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Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice.
Annika Keller, Ana Westenberger, Maria J Sobrido, Maria García-Murias, Aloysius Domingo, Michael Hugelshofer

Nat Genet· September 2013

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