Publications by authors named "Michael Huhn"

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Lung IL-13 gene signatures are associated with raised tissue eosinophils in COPD.
Karl J Staples, Jodie Ackland, Sruthymol Lukose, Bastian Angermann, Graham Belfield

Respir Res· March 2025

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Mapping spatially resolved transcriptomes in human and mouse pulmonary fibrosis.
Lovisa Franzén, Martina Olsson Lindvall, Michael Hühn, Victoria Ptasinski, Laura Setyo

Nat Genet· August 2024

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Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD.
Ventzislava A Hristova, Alastair Watson, Raghothama Chaerkady, Matthew S Glover, Jodie Ackland

ERJ Open Res· May 2023

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Rare variant contribution to human disease in 281,104 UK Biobank exomes.
Quanli Wang, Ryan S Dhindsa, Keren Carss, Andrew R Harper, Abhishek Nag

Nature· September 2021

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Dysregulation of COVID-19 related gene expression in the COPD lung.
Alastair Watson, Lisa Öberg, Bastian Angermann, C Mirella Spalluto, Michael Hühn

Respir Res· May 2021

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Ultrasensitive DNA Immune Repertoire Sequencing Using Unique Molecular Identifiers.
Gustav Johansson, Melita Kaltak, Cristiana Rîmniceanu, Avadhesh K Singh, Jan Lycke

Clin Chem· September 2020

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Dynamics of IFN-β Responses during Respiratory Viral Infection. Insights for Therapeutic Strategies.
Alastair Watson, C Mirella Spalluto, Christopher McCrae, Doriana Cellura, Hannah Burke

Am J Respir Crit Care Med· January 2020

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A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defense.
Emma Svedin, Renata Utorova, Michael H Hühn, Pär G Larsson, Virginia M Stone

J Infect Dis· December 2017

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Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells.
Hannah H Chen, Norman Händel, Joanne Ngeow, James Muller, Michael Hühn

J Allergy Clin Immunol· February 2017

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An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets.
Erna Domsgen, Katharina Lind, Lingjia Kong, Michael H Hühn, Omid Rasool

Sci Rep· December 2016

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Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies.
Dmitrij Hristodorov, Radoslav Mladenov, Verena von Felbert, Michael Huhn, Rainer Fischer

MAbs· June 2016

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Glucocorticoids Suppress CCR9-Mediated Chemotaxis, Calcium Flux, and Adhesion to MAdCAM-1 in Human T Cells.
Emily Wendt, Gemma E White, Helen Ferry, Michael Huhn, David R Greaves

J Immunol· May 2016

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RORγt inhibitors suppress T(H)17 responses in inflammatory arthritis and inflammatory bowel disease.
Jelle de Wit, M Hussein Al-Mossawi, Michael H Hühn, Carolina V Arancibia-Cárcamo, Karen Doig

J Allergy Clin Immunol· March 2016

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Labeling of anti-MUC-1 binding single chain Fv fragments to surface modified upconversion nanoparticles for an initial in vivo molecular imaging proof of principle approach.
Anja Hischemöller, Claudia Walter, Volker Weiler, Helga Hummel, Theo Thepen, Michael Huhn

Int J Mol Sci· August 2015

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Targeted ex vivo reduction of CD64-positive monocytes in chronic myelomonocytic leukemia and acute myelomonocytic leukemia using human granzyme B-based cytolytic fusion proteins.
Sonja Schiffer, Reinhard Rosinke, Edgar Jost, Grit Hehmann-Titt, Michael Huhn

Int J Cancer· September 2014

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EpCAM-selective elimination of carcinoma cells by a novel MAP-based cytolytic fusion protein.
Dmitrij Hristodorov, Manal Amoury, Radoslav Mladenov, Judith Niesen, Katharina Arens, Michael Huhn

Mol Cancer Ther· September 2014

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Human microtubule-associated protein tau mediates targeted killing of CD30(+) lymphoma cells in vitro and inhibits tumour growth in vivo.
Dmitrij Hristodorov, Johannes Nordlohne, Radoslav Mladenov, Michael Huhn, Rainer Fischer

Br J Haematol· January 2014

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Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells.
Sonja Schiffer, Soriba Letzian, Edgar Jost, Radoslav Mladenov, Dmitrij Hristodorov, Michael Huhn

Cancer Lett· December 2013

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Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection.
Cormac Cosgrove, James E Ussher, Andri Rauch, Kathleen Gärtner, Ayako Kurioka

Blood· February 2013

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Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases.
Dmitrij Hristodorov, Radoslav Mladenov, Michael Huhn, Stefan Barth, Theo Thepen

Toxins (Basel)· September 2012

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In vivo efficacy of the recombinant anti-CD64 immunotoxin H22(scFv)-ETA' in a human acute myeloid leukemia xenograft tumor model.
Mehmet Kemal Tur, Michael Huhn, Edgar Jost, Theo Thepen, Tim H Brümmendorf

Int J Cancer· September 2011

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Melanoma differentiation-associated protein-5 (MDA-5) limits early viral replication but is not essential for the induction of type 1 interferons after Coxsackievirus infection.
Michael H Hühn, Stephen A McCartney, Katharina Lind, Emma Svedin, Marco Colonna

Virology· May 2010

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Expression of intestinal and lung alkaline sphingomyelinase and neutral ceramidase in cystic fibrosis f508del transgenic mice.
Lena Ohlsson, Lena Hjelte, Michael Hühn, Bob J Scholte, Martina Wilke

J Pediatr Gastroenterol Nutr· November 2008

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IFN-gamma production dominates the early human natural killer cell response to Coxsackievirus infection.
Michael H Hühn, Monica Hultcrantz, Katharina Lind, Hans-Gustaf Ljunggren, Karl-Johan Malmberg

Cell Microbiol· February 2008

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Immune evasion of the human pathogen Pseudomonas aeruginosa: elongation factor Tuf is a factor H and plasminogen binding protein.
Anja Kunert, Josephine Losse, Christin Gruszin, Michael Hühn, Kerstin Kaendler

J Immunol· September 2007

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