Publications by authors named "Michael Leffak"

Claim this Profile
M
Microsatellite break-induced replication generates highly mutagenized extrachromosomal circular DNAs.
Rujuta Yashodhan Gadgil, S Dean Rider, Resha Shrestha, Venicia Alhawach, David C Hitch, Michael Leffak

NAR Cancer· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Microsatellite break-induced replication generates highly mutagenized extrachromosomal circular DNAs.
Rujuta Yashodhan Gadgil, S Dean Rider, Resha Shrestha, Venicia Alhawach, David C Hitch, Michael Leffak

bioRxiv· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Suppressors of Break-Induced Replication in Human Cells.
Stanley Dean Rider, French J Damewood, Rujuta Yashodhan Gadgil, David C Hitch, Venicia Alhawach, Michael Leffak

Genes (Basel)· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Stable G-quadruplex DNA structures promote replication-dependent genome instability.
S Dean Rider, Rujuta Yashodhan Gadgil, David C Hitch, French J Damewood, Nathen Zavada, Michael Leffak

J Biol Chem· June 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Analysis of Trinucleotide Repeat Stability by Integration at a Chromosomal Ectopic Site.
Rujuta Yashodhan Gadgil, S Dean Rider, Todd Lewis, Joanna Barthelemy, Michael Leffak

Methods Mol Biol· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Replication stress at microsatellites causes DNA double-strand breaks and break-induced replication.
Rujuta Yashodhan Gadgil, Eric J Romer, Caitlin C Goodman, S Dean Rider, French J Damewood, Michael Leffak

J Biol Chem· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Deficiency of the Fanconi anemia E2 ubiqitin conjugase UBE2T only partially abrogates Alu-mediated recombination in a new model of homology dependent recombination.
Todd W Lewis, Joanna R Barthelemy, Elizabeth L Virts, Felicia M Kennedy, Rujuta Y Gadgil, Michael Leffak

Nucleic Acids Res· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells.
Sumeet Poudel, Jianhong Yao, Michael G Kemp, Michael Leffak

J Biol Chem· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Break-induced replication links microsatellite expansion to complex genome rearrangements.
Michael Leffak

Bioessays· August 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
FANCJ is essential to maintain microsatellite structure genome-wide during replication stress.
Joanna Barthelemy, Helmut Hanenberg, Michael Leffak

Nucleic Acids Res· January 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
FANCJ is essential to maintain microsatellite structure genome-wide during replication stress.
Joanna Barthelemy, Helmut Hanenberg, Michael Leffak

Nucleic Acids Res· August 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MutSβ promotes trinucleotide repeat expansion by recruiting DNA polymerase β to nascent (CAG)n or (CTG)n hairpins for error-prone DNA synthesis.
Jinzhen Guo, Liya Gu, Michael Leffak, Guo-Min Li

Cell Res· July 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia.
Elizabeth L Virts, Anna Jankowska, Craig Mackay, Marcel F Glaas, Constanze Wiek, Michael Leffak

Hum Mol Genet· September 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation.
Yanzhe Gao, Jianhong Yao, Sumeet Poudel, Eric Romer, Lubna Abu-Niaaj, Michael Leffak

J Biol Chem· December 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Activation of a human chromosomal replication origin by protein tethering.
Xiaomi Chen, Guoqi Liu, Michael Leffak

Nucleic Acids Res· July 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Hypothesis: local dNTP depletion as the cause of microsatellite repeat instability during replication (comment on DOI 10.1002/bies.201200128).
Michael Leffak

Bioessays· April 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Oligodeoxynucleotide binding to (CTG) · (CAG) microsatellite repeats inhibits replication fork stalling, hairpin formation, and genome instability.
Guoqi Liu, Xiaomi Chen, Michael Leffak

Mol Cell Biol· February 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Replication fork stalling and checkpoint activation by a PKD1 locus mirror repeat polypurine-polypyrimidine (Pu-Py) tract.
Guoqi Liu, Sheré Myers, Xiaomi Chen, John J Bissler, Richard R Sinden, Michael Leffak

J Biol Chem· September 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Treslin, DUE-B, and GEMC1 cannot complement Sld3 mutants in fission yeast.
Zhuo Wang, Elaine Kim, Michael Leffak, Yong-Jie Xu

FEMS Yeast Res· June 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Altered replication in human cells promotes DMPK (CTG)(n) · (CAG)(n) repeat instability.
Guoqi Liu, Xiaomi Chen, Yanzhe Gao, Todd Lewis, Joanna Barthelemy, Michael Leffak

Mol Cell Biol· May 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesis.
Guoqi Liu, Michael Leffak

Cell Biosci· February 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Replication-dependent instability at (CTG) x (CAG) repeat hairpins in human cells.
Guoqi Liu, Xiaomi Chen, John J Bissler, Richard R Sinden, Michael Leffak

Nat Chem Biol· September 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
ATRIP from TopBP1 to ATR--in vitro activation of a DNA damage checkpoint.
Yong-jie Xu, Michael Leffak

Proc Natl Acad Sci U S A· August 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Unstable spinocerebellar ataxia type 10 (ATTCT*(AGAAT) repeats are associated with aberrant replication at the ATX10 locus and replication origin-dependent expansion at an ectopic site in human cells.
Guoqi Liu, John J Bissler, Richard R Sinden, Michael Leffak

Mol Cell Biol· November 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure and function of the c-myc DNA-unwinding element-binding protein DUE-B.
Michael Kemp, Brian Bae, John Paul Yu, Maloy Ghosh, Michael Leffak

J Biol Chem· April 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis