Publications by authors named "Brian Bae"

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Characterization of the flavin monooxygenase involved in biosynthesis of the antimalarial FR-900098.
Kim Nguyen, Matthew A DeSieno, Brian Bae, Tyler W Johannes, Ryan E Cobb

Org Biomol Chem· February 2019

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RNA polymerase motions during promoter melting.
Andrey Feklistov, Brian Bae, Jesse Hauver, Agnieszka Lass-Napiorkowska, Markus Kalesse

Science· May 2017

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Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.
Ashley L Garner, Jayan Rammohan, Jeremy P Huynh, Lucas M Onder, James Chen, Brian Bae

J Bacteriol· February 2017

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Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
Brian Bae, Andrey Feklistov, Agnieszka Lass-Napiorkowska, Robert Landick, Seth A Darst

Elife· September 2015

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CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.
Brian Bae, James Chen, Elizabeth Davis, Katherine Leon, Seth A Darst

Elife· September 2015

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CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Brian Bae, Dhananjaya Nayak, Ananya Ray, Arkady Mustaev, Robert Landick

Proc Natl Acad Sci U S A· August 2015

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Structure-guided design and biosynthesis of a novel FR-900098 analogue as a potent Plasmodium falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Dxr) inhibitor.
Ryan E Cobb, Brian Bae, Zhi Li, Matthew A DeSieno, Satish K Nair

Chem Commun (Camb)· February 2015

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Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of σ70 domain 1.1.
Brian Bae, Elizabeth Davis, Daniel Brown, Elizabeth A Campbell, Sivaramesh Wigneshweraraj

Proc Natl Acad Sci U S A· December 2013

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Biochemical and structural insights into xylan utilization by the thermophilic bacterium Caldanaerobius polysaccharolyticus.
Yejun Han, Vinayak Agarwal, Dylan Dodd, Jason Kim, Brian Bae

J Biol Chem· October 2012

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New N-acetyltransferase fold in the structure and mechanism of the phosphonate biosynthetic enzyme FrbF.
Brian Bae, Ryan E Cobb, Matthew A DeSieno, Huimin Zhao, Satish K Nair

J Biol Chem· October 2011

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Structural and functional analyses of a glycoside hydrolase family 5 enzyme with an unexpected β-fucosidase activity.
Shosuke Yoshida, David S Park, Brian Bae, Roderick Mackie, Isaac K O Cann

Biochemistry· April 2011

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Mutational insights into the roles of amino acid residues in ligand binding for two closely related family 16 carbohydrate binding modules.
Xiaoyun Su, Vinayak Agarwal, Dylan Dodd, Brian Bae, Roderick I Mackie

J Biol Chem· November 2010

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Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis.
Jin-Hee Lee, Brian Bae, Michael Kuemin, Benjamin T Circello, William W Metcalf

Proc Natl Acad Sci U S A· October 2010

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Structure and engineering of L-arabinitol 4-dehydrogenase from Neurospora crassa.
Brian Bae, Ryan P Sullivan, Huimin Zhao, Satish K Nair

J Mol Biol· September 2010

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Insights into the architecture of the replicative helicase from the structure of an archaeal MCM homolog.
Brian Bae, Yi-Hsing Chen, Alessandro Costa, Silvia Onesti, Joseph S Brunzelle

Structure· February 2009

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Molecular basis for the selectivity and specificity of ligand recognition by the family 16 carbohydrate-binding modules from Thermoanaerobacterium polysaccharolyticum ManA.
Brian Bae, Samuel Ohene-Adjei, Svetlana Kocherginskaya, Roderick I Mackie, M Ashley Spies

J Biol Chem· May 2008

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Structure and function of the c-myc DNA-unwinding element-binding protein DUE-B.
Michael Kemp, Brian Bae, John Paul Yu, Maloy Ghosh, Michael Leffak

J Biol Chem· April 2007

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