Publications by authors named "Michael N Alexis"

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ERβ1 Sensitizes and ERβ2 Desensitizes ERα-Positive Breast Cancer Cells to the Inhibitory Effects of Tamoxifen, Fulvestrant and Their Combination with All-Trans Retinoic Acid.
Aggeliki K Meligova, Dimitra Siakouli, Sotiria Stasinopoulou, Despoina S Xenopoulou, Maria Zoumpouli, Michael N Alexis

Int J Mol Sci· February 2023

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The brominated flame retardants TBECH and DPTE alter prostate growth, histology and gene expression patterns in the mouse.
Ceyhun Bereketoglu, Carina Modig, Ajay Pradhan, Patrik L Andersson, Sotiria Stasinopoulou, Michael N Alexis

Reprod Toxicol· June 2021

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Design, synthesis, and biological evaluation of new raloxifene analogues of improved antagonist activity and endometrial safety.
George Lambrinidis, Cedric Gouedard, Sotiria Stasinopoulou, Angeliki Angelopoulou, Vassiliki Ganou, Michael N Alexis

Bioorg Chem· January 2021

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Natural and Nature-Derived Products Targeting Human Coronaviruses.
Konstantina Vougogiannopoulou, Angela Corona, Enzo Tramontano, Michael N Alexis, Alexios-Leandros Skaltsounis

Molecules· January 2021

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Isoflavonoid Profiling and Estrogen-Like Activity of Four Species from the Greek Flora.
Antigoni Cheilari, Argyro Vontzalidou, Maria Makropoulou, Aggeliki K Meligova, Nikolas Fokialakis, Michael N Alexis

Molecules· November 2020

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Biological evaluation of isoflavonoids from Genista halacsyi using estrogen-target cells: Activities of glucosides compared to aglycones.
Nikolas Fokialakis, Xanthippi Alexi, Nektarios Aligiannis, Athina Boulaka, Aggeliki K Meligova, Michael N Alexis

PLoS One· October 2019

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Discovery of New non-steroidal selective glucocorticoid receptor agonists.
Constantinos Potamitis, Dimitra Siakouli, Konstantinos D Papavasileiou, Athina Boulaka, Vassiliki Ganou, Michael N Alexis

J Steroid Biochem Mol Biol· February 2019

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Biological and computational evaluation of resveratrol inhibitors against Alzheimer's disease.
Catherine Koukoulitsa, Caroline Villalonga-Barber, Robert Csonka, Xanthippi Alexi, Georgios Leonis, Michael N Alexis

J Enzyme Inhib Med Chem· October 2016

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Phytochemical study and biological evaluation of chemical constituents of Platanus orientalis and Platanus × acerifolia buds.
Quoc Dang Thai, Job Tchoumtchoua, Maria Makropoulou, Athina Boulaka, Aggeliki K Meligova, Michael N Alexis

Phytochemistry· October 2016

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Estrogenic activity of isoflavonoids from the stem bark of the tropical tree Amphimas pterocarpoides, a source of traditional medicines.
Job Tchoumtchoua, Maria Makropoulou, Sylvain Benjamin Ateba, Athina Boulaka, Maria Halabalaki, Michael N Alexis

J Steroid Biochem Mol Biol· April 2016

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Elucidation of the binding mechanism of renin using a wide array of computational techniques and biological assays.
Haralambos Tzoupis, Georgios Leonis, Aggelos Avramopoulos, Heribert Reis, Żaneta Czyżnikowska, Michael N Alexis

J Mol Graph Model· November 2015

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Perinatal exposure to low-dose bisphenol A affects the neuroendocrine stress response in rats.
Emily Panagiotidou, Sophia Zerva, Dimitra J Mitsiou, Michael N Alexis, Efthymia Kitraki

J Endocrinol· March 2014

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Pharmacoproteomic study of the natural product Ebenfuran III in DU-145 prostate cancer cells: the quantitative and temporal interrogation of chemically induced cell death at the protein level.
Theodoros I Roumeliotis, Maria Halabalaki, Xanthippi Alexi, Dyan Ankrett, Eugenia G Giannopoulou, Michael N Alexis

J Proteome Res· April 2013

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Peltogynoids and 2-phenoxychromones from Peltophorum pterocarpum and evaluation of their estrogenic activity.
Johanne Polasek, Emerson Ferreira Queiroz, Laurence Marcourt, Aggeliki K Meligova, Maria Halabalaki, Michael N Alexis

Planta Med· April 2013

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Ester and carbamate ester derivatives of Biochanin A: synthesis and in vitro evaluation of estrogenic and antiproliferative activities.
Nikolas Fokialakis, Xanthippi Alexi, Nektarios Aligiannis, Despina Siriani, Aggeliki K Meligova, Michael N Alexis

Bioorg Med Chem· May 2012

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Insights into ectopic estrogen receptor expression, nucleocytoplasmic distribution and interaction with chromatin obtained with new antibodies to estrogen receptors α and β.
Niki I Chantzi, Aggeliki K Meligova, Eugen Dhimolea, Christos C Petrou, Dimitra J Mitsiou, Michael N Alexis

Steroids· November 2011

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Coactivation of GR and NFKB alters the repertoire of their binding sites and target genes.
Nagesha A S Rao, Melysia T McCalman, Panagiotis Moulos, Kees-Jan Francoijs, Aristotelis Chatziioannou, Michael N Alexis

Genome Res· September 2011

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Isoxazole substituted chromans against oxidative stress-induced neuronal damage.
Maria Koufaki, Alexandra Tsatsaroni, Xanthippi Alexi, Helène Guerrand, Sofia Zerva, Michael N Alexis

Bioorg Med Chem· August 2011

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Comparison of thermal effects of stilbenoid analogs in lipid bilayers using differential scanning calorimetry and molecular dynamics: correlation of thermal effects and topographical position with antioxidant activity.
Catherine Koukoulitsa, Serdar Durdagi, Eleni Siapi, Carolina Villalonga-Barber, Xanthippi Alexi, Michael N Alexis

Eur Biophys J· July 2011

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New hydroxystilbenoid derivatives endowed with neuroprotective activity and devoid of interference with estrogen and aryl hydrocarbon receptor-mediated transcription.
Carolina Villalonga-Barber, Aggeliki K Meligova, Xanthippi Alexi, Barry R Steele, Constantinos E Kouzinos, Michael N Alexis

Bioorg Med Chem· January 2011

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Synthesis of a second generation chroman/catechol hybrids and evaluation of their activity in protecting neuronal cells from oxidative stress-induced cell death.
Maria Koufaki, Elissavet Theodorou, Xanthippi Alexi, Michael N Alexis

Bioorg Med Chem· June 2010

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Erymildbraedin A and B, two novel cytotoxic dimethylpyrano-isoflavones from the stem bark of Erythrina mildbraedii: evaluation of their activity toward endocrine cancer cells.
Ruben F Tchokouaha, Xanthippi Alexi, Elizabeth Chosson, Thierry Besson, Alexios-Leandros Skaltsounis, Michael N Alexis

J Enzyme Inhib Med Chem· April 2010

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Synthesis of tropolone derivatives and evaluation of their in vitro neuroprotective activity.
Maria Koufaki, Elissavet Theodorou, Xanthippi Alexi, Faidra Nikoloudaki, Michael N Alexis

Eur J Med Chem· March 2010

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Differential estrogen receptor subtype modulators: assessment of estrogen receptor subtype-binding selectivity and transcription-regulating properties of new cycloalkyl pyrazoles.
Xanthippi Alexi, Konstantinos M Kasiotis, Nikolaos Fokialakis, George Lambrinidis, Aggeliki K Meligova, Michael N Alexis

J Steroid Biochem Mol Biol· November 2009

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Novel dehydroepiandrosterone derivatives with antiapoptotic, neuroprotective activity.
Theodora Calogeropoulou, Nicolaos Avlonitis, Vassilios Minas, Xanthippi Alexi, Athanasia Pantzou, Michael N Alexis

J Med Chem· November 2009

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